Results 111 to 120 of about 31,173 (261)
Comparison of Bulbar and Mucosal Olfactory Ensheathing Cells Using FACS and Simultaneous Antigenic Bivariate Cell Cycle Analysis [PDF]
Transplantation of olfactory ensheathing cells (OECs) is a promising route for CNS repair. There have, however, been major discrepancies between the results from different groups.
Kueh, JLL +4 more
core
Injury in Aged Animals Robustly Activates Quiescent Olfactory Neural Stem Cells [PDF]
While the capacity of the olfactory epithelium (OE) to generate sensory neurons continues into middle age in mice, it is presumed that this regenerative potential is present throughout all developmental stages.
Brann, Jessica H. +4 more
core +2 more sources
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
Postnatal odorant exposure induces peripheral olfactory plasticity at the cellular level [PDF]
Mammalian olfactory sensory neurons (OSNs) form the primary elements of the olfactory system. Inserted in the olfactory mucosa lining of the nasal cavity, they are exposed to the environment and their lifespan is brief.
AOUDE, Imad +6 more
core +3 more sources
The Olfactory Mucosa of the Sheep [PDF]
The olfactory mucosa of the sheep was studied by light and electron microscopy. The epithelium conforms to the general vertebrate pattern and consists of olfactory receptor cells, supporting, and basal cells. The free edge of the epithelium is made up of long microvilli from the supporting cells and olfactory rods of the receptor cells, each carrying ...
openaire +2 more sources
ABSTRACT Primary diffuse type 2‐dominant chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease of the nasal cavity and paranasal sinuses associated with significant morbidity. Impaired sense of smell is a cardinal symptom of CRSwNP and one of the most burdensome for patients, impacting quality of life, mental health, and even ...
Thomas S. Higgins +9 more
wiley +1 more source
Distribution of α7 Nicotinic Acetylcholine Receptor Subunit mRNA in the Developing Mouse. [PDF]
Homomeric α7 nicotinic acetylcholine receptors (nAChRs) are abundantly expressed in the central and peripheral nervous system (CNS and PNS, respectively), and spinal cord.
Broide, Ron S +3 more
core +1 more source
Nose-to-brain delivery of antiviral drugs: A way to overcome their active efflux? [PDF]
Although several viruses can easily infect the central nervous system (CNS), antiviral drugs often show dramatic difficulties in penetrating the brain from the bloodstream since they are substrates of active efflux transporters (AETs). These transporters,
Dalpiaz, Alessandro, Pavan, Barbara
core +2 more sources
Traditional Chinese medicine (TCM) faces great challenges during the development of modern medicine. Utilizing novel technologies such as artificial intelligence (AI) and nanotechnology facilitates TCM with great potential in precision diagnosis and improved treatments efficacy.
Wenqi Yu +7 more
wiley +1 more source
Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets
The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang +6 more
wiley +1 more source

