Results 91 to 100 of about 447,033 (267)

Could Cells from Your Nose Fix Your Heart? Transplantation of Olfactory Stem Cells in a Rat Model of Cardiac Infarction

open access: yesThe Scientific World Journal, 2010
This study examines the hypothesis that multipotent olfactory mucosal stem cells could provide a basis for the development of autologous cell transplant therapy for the treatment of heart attack.
Cameron McDonald   +3 more
doaj   +1 more source

Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium.

open access: yesPLoS ONE, 2012
BackgroundP-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP1) are membrane transporter proteins which function as efflux pumps at cell membranes and are considered to exert a protective function against the entry of xenobiotics. While
Adrien Molinas   +2 more
doaj   +1 more source

Squamous and Respiratory Metaplasia After Olfactory Mucosal Resection

open access: yesFrontiers in Neuroscience, 2021
Resection of the olfactory mucosa (OM) is sometimes unavoidable during surgery; however, it is not known whether the OM can completely recover thereafter.
Eri Mori   +11 more
doaj   +1 more source

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia

open access: yesScientific Reports, 2017
Fatal Familial Insomnia (FFI) is a genetic prion disease caused by a point mutation in the prion protein gene (PRNP) characterized by prominent thalamic atrophy, diffuse astrogliosis and moderate deposition of PrPSc in the brain. Here, for the first time,
V. Redaelli   +14 more
semanticscholar   +1 more source

Computational exploration of molecular receptive fields in the olfactory bulb reveals a glomerulus-centric chemical map [PDF]

open access: yes, 2020
© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Progress in olfactory research is currently hampered by ...
A Nagashima   +50 more
core   +2 more sources

Reprogramming Antitumor Immunity: NK Cell Strategies to Navigate the Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs   +4 more
wiley   +1 more source

Prion shedding from olfactory neurons into nasal secretions. [PDF]

open access: yesPLoS Pathogens, 2010
This study investigated the role of prion infection of the olfactory mucosa in the shedding of prion infectivity into nasal secretions. Prion infection with the HY strain of the transmissible mink encephalopathy (TME) agent resulted in a prominent ...
Richard A Bessen   +7 more
doaj   +1 more source

Competence, specification and commitment to an olfactory placode fate [PDF]

open access: yes, 2008
The nasal placode shares a common origin with other sensory placodes within a pre-placodal domain at the cranial neural plate border. However, little is known about early events in nasal placode development as it segregates from prospective lens, neural ...
Bhattacharyya, Sujata   +1 more
core   +2 more sources

The use of platelet-rich plasma in treatment of olfactory dysfunction: A pilot study. [PDF]

open access: yes, 2020
BackgroundOlfactory dysfunction is a prevalent problem with a significant impact on quality of life and increased mortality. Limited effective therapies exist.
Mundy, David C   +2 more
core   +1 more source

Appropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy