Results 111 to 120 of about 18,254 (242)
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang +6 more
wiley +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Localization and Distribution of Human Olfactory Mucosa in the Nasal Cavities [PDF]
Introduction: The exact distribution of the human olfactory mucosa can only be determined in studies that evaluate the entire olfactory region. The purpose of this study is to determine the distribution of human olfactory mucosa in the nasal cavities, by
Escada, Pedro
core
Identification of Immune Cells in Murine Olfactory Mucosa. [PDF]
Wellford SA, Moseman EA.
europepmc +1 more source
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs +4 more
wiley +1 more source
All images are from in vitro cell cultures except image I obtained from an olfactory mucosa biopsy. Upper layer (A)(B)(C): cells obtained via rhinotomy; middle layer (D)(E): cells obtained via keyhole approach; and right middle and bottom layer (F)(G)(H):
Daisuke Ito (95901) +6 more
core +1 more source
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park +9 more
wiley +1 more source
Isolation of Adult Stem Cells from the Human Olfactory Mucosa
The olfactory mucosa, located in the nasal cavity, is the only nervous tissue that is exposed to the external environment and easily accessible in every living individual.
Stéphane D. Girard +7 more
core +1 more source
Human-derived air-liquid interface cultures decipher Alzheimer's disease-SARS-CoV-2 crosstalk in the olfactory mucosa. [PDF]
Shahbaz MA +19 more
europepmc +1 more source

