Results 111 to 120 of about 447,033 (267)

SB203580, a p38MAPK inhibitor, attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mice (activation and involvement of the p38 mitogen‐activated protein kinase in olfactory sensory neuronal apoptosis of OVA‐induced allergic rhinitis)

Brain and Behavior, 2019
Objective This study aimed to investigate the effect of the p38 mitogen‐activated protein kinase (p38MAPK) signaling pathway on olfactory mucosa function and apoptosis of olfactory sensory neurons (OSNs) in an allergic rhinitis (AR) mouse model.
Xian Gao, Na Li, Jisheng Zhang
doaj   +1 more source

Immunological status of the olfactory bulb in a murine model of Toll-like receptor 3-mediated upper respiratory tract inflammation

Journal of Neuroinflammation, 2022
Background Postviral olfactory dysfunction (PVOD) following a viral upper respiratory tract infection (URI) is one of the most common causes of olfactory disorders, often lasting for over a year.
Ryoji Kagoya, Makiko Toma-Hirano, Junya Yamagishi, Naoyuki Matsumoto, Kenji Kondo, Ken Ito   +5 more
doaj   +1 more source

Functional anatomy of olfactory sense organs [PDF]

, 1976
The olfactory organ is the most primitive of the organs of special sense and the one with the simplest structural organization, and yet it has defied a clear exposition of the way in which it perceives and distinguishes between different odours.
Cuschieri, Alfred
core  

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

Autism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni, Lisa Asta, Nicole Giompaolo, Rinvil Renaldi, Alberto Amaretti, Maddalena Rossi, Antonio M. Persico   +6 more
wiley   +1 more source

Toxicological effects of volatile organic compounds are mediated by aggravated oxidative stress and neuroinflammatory processes in piglets

Toxicology Reports
Anthropogenic and natural sources of volatile organic compounds (VOCs) have been associated with hematological, cardiovascular, and respiratory diseases. VOCs can also track directly from the nose to the olfactory bulb (OB).
Evaristus Nwulia, Temitayo Olabisi Ajibade, Charles Etang Onukak, Oluwaseun Olarenwaju Esan, John Olusoji Abiola, Temidayo Olutayo Omobowale, Olanrewaju Samuel Olaifa, Olugbenga Olayinka Alaka, Olumayowa Olawumi Igado, Adedunsola Adewunmi Obasa, Godson Ana, Olubukola Christiana Omobowale, Maria Hipolito, Opeyemi Mercy Awofeso, Abimbola Idowu, Ademola Adetokunbo Oyagbemi   +15 more
doaj   +1 more source

Odorant metabolism catalyzed by olfactory mucosal enzymes influences peripheral olfactory responses in rats. [PDF]

PLoS ONE, 2013
A large set of xenobiotic-metabolizing enzymes (XMEs), such as the cytochrome P450 monooxygenases (CYPs), esterases and transferases, are highly expressed in mammalian olfactory mucosa (OM).
Nicolas Thiebaud, Stéphanie Veloso Da Silva, Ingrid Jakob, Gilles Sicard, Joëlle Chevalier, Franck Ménétrier, Olivier Berdeaux, Yves Artur, Jean-Marie Heydel, Anne-Marie Le Bon   +9 more
doaj   +1 more source

Olfactory mucosa in herpes simplex encephalitis. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1979
The olfactory mucosa was examined in three patients dying from herpes simplex encephalitis. It showed changes attributed to infection by the herpes simplex virus. It is suggested that in some patients encephalitis may be a complication of infection of the olfactory mucosa.
J A, Twomey, C M, Barker, G, Robinson, D A, Howell   +3 more
openaire   +2 more sources

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Secretome of Olfactory Mucosa Mesenchymal Stem Cell, a Multiple Potential Stem Cell

Stem Cells International, 2016
Nasal olfactory mucosa mesenchymal stem cells (OM-MSCs) have the ability to promote regeneration in the nervous system in vivo. Moreover, with view to the potential for clinical application, OM-MSCs have the advantage of being easily accessible from ...
Lite Ge, Miao Jiang, D. Duan, Zijun Wang, Linyu Qi, X. Teng, Zhenyu Zhao, Lei Wang, Y. Zhuo, Ping Chen, Xijing He, Ming Lu   +11 more
semanticscholar   +1 more source

Nose [PDF]

, 2008
Histology blog entry for October 17, 2008 about the ...
Krause, William J., II, 1942-
core   +1 more source