Results 101 to 110 of about 229,983 (244)

Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa

Frontiers in Aging Neuroscience, 2018
Background: The incidence of olfactory impairment increases with age; however, the detailed molecular and cellular mechanisms underlying this increase are yet to be determined.Methods: We examined the influence of aging on olfactory receptor neurons ...
Rumi Ueha, Shigeyuki Shichino, Satoshi Ueha, Kenji Kondo, Shu Kikuta, Hironobu Nishijima, Kouji Matsushima, Tatsuya Yamasoba   +7 more
doaj   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy, Lei Cheng, De‐Yun Wang   +2 more
wiley   +1 more source

Linkage between increased nociception and olfaction via a SCN9A haplotype [PDF]

, 2013
Background and Aims: Mutations reducing the function of Nav1.7 sodium channels entail diminished pain perception and olfactory acuity, suggesting a link between nociception and olfaction at ion channel level.
Hummel, Thomas, Bruno G Oertel, Lötsch, Jörn, Thomas Hummel, Jörn Lötsch, Doehring, Alexandra, Dirk Heimann, Heimann, Dirk, Alexandra Doehring, Oertel, Bruno Georg   +9 more
core   +2 more sources

Alterations in Nasal Function Following Total Laryngectomy and Their Clinical Correlates

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Although nasal structural and functional changes after total laryngectomy (TL) have been documented, the influence of clinical variables and symptoms remains underexplored. This study compared nasal structure and function between TL patients and healthy controls and identified clinical factors associated with these changes ...
Kajornpan Sermwittayawong, Paraya Assanasen, Phawin Keskool, Dichapong Kanjanawasee   +3 more
wiley   +1 more source

Microsurgical anatomy of the olfactory filaments in the nasal mucosa

Journal of Neurosurgery
OBJECTIVE The aim of this study was to examine the distribution of olfactory filaments (OFs) in the nasal mucosa to facilitate preservation of olfactory function in endonasal approaches and preparation of a nasoseptal flap. METHODS One formalin-fixed and 9 fresh cadaveric silicone-injected specimens with 20 total sides were studied to measure the ...
Ilgaz, Hasan Baris, Urgun, Kamran, Yener, Ulas, Mut, Melike, Liu, James K., Yagmurlu, Kaan   +5 more
openaire   +4 more sources

The Usefulness of Machine Learning Models to Predict Patient‐Reported Outcome Measures in Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background and Objective The treatment available for chronic rhinosinusitis with nasal polyps (CRSwNP) has remained unsatisfactory. Patient‐reported outcome measures (PROMs), capturing patient‐perceived health status and well‐being, are vehicles for measuring and improving the efficacy of care.
Yang Shen, Pan‐Hui Xiong, Bo‐Wen Zheng, Chen‐Xi Li, Jun‐Liang Chen, Yue Gu, Yan‐Han Yang, Tao Lu, Yu‐Cheng Yang   +8 more
wiley   +1 more source

AI‐Powered TAT‐Net Hyperspectral Imaging for Rapid and Accurate Differentiation of Sinonasal Inverted Papilloma and Malignancy

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal inverted papilloma (IP) and malignancies share overlapping clinical and endoscopic features, and conventional histopathology frequently requires time‐consuming adjunct immunohistochemistry. Hyperspectral imaging (HSI) can capture subtle spectral changes associated with malignant transformation that are not apparent on ...
Hao‐Miao Zhao, Jia‐Chang Kong, Yun‐Ze Li, Wei Li, Xin Feng   +4 more
wiley   +1 more source

Volatile Compounds in Feathers of the Scarlet Macaw (Ara macao) Reflect Sex and Pair‐Bond Status

Integrative Zoology, EarlyView.
Scarlet macaws exhibit sex‐ and pair‐related differences in plumage volatile composition, with males showing greater chemical richness. Partnered individuals differ in specific compound classes, whereas no clear association with immune function was detected. These results support a potential role for olfactory cues in sexual and social communication in
Elisa Espartosa, Isabel Barja, José Martin, María del Carmen Hernández   +3 more
wiley   +1 more source

Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper

Allergy, EarlyView.
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg, Julie van Waterschoot, Mathilde Moyaert, Adam Chaker, Philippe Gevaert, Jan Hagemann, Valérie Hox, Maarten Kleijwegt, Ludger Klimek, Devyani Lal, Juan Maza‐Solano, Oliver Pfaar, Fabio Simon Ryser, Michele Shiappoli, Diana Silva, Sanna Toppila‐Salmi, Johanna Wikstén, Sietze Reitsma, Laura Van Gerven   +18 more
wiley   +1 more source

Efficacy of Full and Limited Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Nasal Polyps: A Randomised Controlled Trial

Allergy, EarlyView.
Both Full and Limited FESS result in clinically meaningful relief of disease‐specific HRQoL and nasal breathing, effectively improving nasal symptoms and sleep disturbance in CRSwNP patients. Clinically meaningful difference in decrease of SNOT‐22 scores between the groups was not found at 12‐ and 24–month follow‐up.
P. Virkkula, S. Hammarén‐Malmi, A. Laulajainen‐Hongisto, M. Lilja, J. Wikstén, L. Hafrén, P. Kauppi, S. Reitsma, K. Pajala, J. Sahlman, S. Toppila‐Salmi   +10 more
wiley   +1 more source