Results 71 to 80 of about 16,659 (194)

Methods of olfactory ensheathing cell harvesting from the olfactory mucosa in dogs.

PLoS ONE, 2019
Olfactory ensheathing cells are thought to support regeneration and remyelination of damaged axons when transplanted into spinal cord injuries. Following transplantation, improved locomotion has been detected in many laboratory models and in dogs with ...
Daisuke Ito, Darren Carwardine, Jon Prager, Liang Fong Wong, Masato Kitagawa, Nick Jeffery, Nicolas Granger   +6 more
doaj   +1 more source

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

Journal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury, Bethany Dickson, Nicola Curtis, David Bunton, Kirsty Goncalves, Stefan Przyborski   +5 more
wiley   +1 more source

Study on the mechanism of electroacupuncture in improving olfactory function in rats with allergic rhinitis-induced olfactory dysfunction through inhibition of inflammatory response

针刺研究
ObjectiveTo observe the effects of electroacupuncture （EA） on olfactory function， olfactory epithelial cell apoptosis， olfactory marker protein （OMP）， cysteinyl aspartate-specific protease-3 （Caspase-3）， and the expression of inflammatory factors in rats
ZHOU Ke-an, WANG Yu-jia, ZHOU Yu-ling, LU Xiao-xiao, ZHANG Qian, HOU Xun-rui, LI Li-hong   +6 more
doaj  

Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa

Frontiers in Aging Neuroscience, 2018
Background: The incidence of olfactory impairment increases with age; however, the detailed molecular and cellular mechanisms underlying this increase are yet to be determined.Methods: We examined the influence of aging on olfactory receptor neurons ...
Rumi Ueha, Shigeyuki Shichino, Satoshi Ueha, Kenji Kondo, Shu Kikuta, Hironobu Nishijima, Kouji Matsushima, Tatsuya Yamasoba   +7 more
doaj   +1 more source

Computed Tomographic Volumetric Analysis of the Nasal Cavities in Domestic Cats (Felis catus) and Anatomical Implications for Intranasal Drug Delivery

Anatomia, Histologia, Embryologia, Volume 55, Issue 5, September 2026.
ABSTRACT To perform a computed tomography (CT)‐based volumetric assessment of the nasal cavities in domestic cats and to evaluate the relationship between nasal cavity volume and selected morphometric variables. Fifty‐six European cats that underwent CT examination of the head were retrospectively included.
Montel Charles, Charlier Hippolyte, Paquet Charlène, Jourdan Géraldine, Mogicato Giovanni   +4 more
wiley   +1 more source

Olfactory mucosa immunostaining v1

, 2023
This protocol describes the immunostaining of olfactory mucosa cells after cocnentrating and depositing a monolayer of the cell suspension onto a slide. For the preparation of the olfactory mucosa suspension refer to protocol "Olfactory mucosa sampling and processing" : dx.doi.org/10.17504/protocols.io.14egn2b86g5d/v1
openaire   +1 more source

Molecular Docking‐Guided Engineering of TPGS/Tween 80 Mixed Micelles for the Intranasal Delivery of Paliperidone Palmitate

Advanced Therapeutics, Volume 9, Issue 8, August 2026.
A nanoscale drug delivery system is developed to improve how an antipsychotic reaches the brain. Using computer‐guided design, mixed micelles are engineered to enhance drug solubility and nasal transport. The system shows improved release and effectiveness in animal models, reducing symptoms while maintaining brain safety and structure.
Poorva Maske, Rati Kailash Prasad Tripathi, Singdha Das Mandal, Pranav Shah, Nimeet Desai, Manisha Lalan   +5 more
wiley   +1 more source

Effect of acupoint injection on olfactory dysfunction and apoptosis of olfactory mucosal cells in rats with allergic rhinitis

针刺研究
ObjectiveTo observe the effect of acupoint injection on olfactory function， olfactory mucosa structure， olfactory mucosa apoptosis and apoptosis-related protein expression in rats with olfactory dysfunction of allergic rhinitis （AR）， so as to explore its
SHI Jia-hui, LIANG Xin, LU Xiao-xiao, HOU Xun-rui, DAI Fang-ying, LUO Xiao-ting, LI Li-hong   +6 more
doaj  

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

International Forum of Allergy &Rhinology, Volume 16, Issue 8, Page 778-787, August 2026.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel, Phillip A. Engen, Glen D. Souza, Sarah Khalife, Donyea Moore, Lauren Kret, Pedro Escobedo, Stefan J. Green, Ankur Naqib, Peter Filip, Peter Papagiannopoulos, Bobby A. Tajudeen, Mahboobeh Mahdavinia, Pete S. Batra   +13 more
wiley   +1 more source

IFN-λ Decreases Murid Herpesvirus-4 Infection of the Olfactory Epithelium but Fails to Prevent Virus Reactivation in the Vaginal Mucosa

Viruses, 2019
Murid herpesvirus-4 (MuHV-4), a natural gammaherpesvirus of rodents, can infect the mouse through the nasal mucosa, where it targets sustentacular cells and olfactory neurons in the olfactory epithelium before it propagates to myeloid cells and then to B
Sophie Jacobs, Caroline Zeippen, Fanny Wavreil, Laurent Gillet, Thomas Michiels   +4 more
doaj   +1 more source