Results 61 to 70 of about 18,254 (242)
The Scientific World Journal, 2010 This study examines the hypothesis that multipotent olfactory mucosal stem cells could provide a basis for the development of autologous cell transplant therapy for the treatment of heart attack.
Cameron McDonald +3 more
doaj +1 more source
Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium.
PLoS ONE, 2012 BackgroundP-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP1) are membrane transporter proteins which function as efflux pumps at cell membranes and are considered to exert a protective function against the entry of xenobiotics. While
Adrien Molinas +2 more
doaj +1 more source
OLFACTORY BULB POTENTIALS TO ELECTRICAL STIMULATION OF THE OLFACTORY MUCOSA
The Japanese Journal of Physiology, 1961 The properties of the olfactory bulb potential evoked by electrical stimulation of the olfactory mucosa were studied in rabbits immobilized with d-tubocurarine. The evoked potential was a slow negative wave when recorded from the surface of the bulb.
openaire +3 more sources
BMEMat, EarlyView.A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie +12 more
wiley +1 more source
Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain
Exploration, EarlyView.The mechanisms underlying solute clearance from the brain parenchyma remain debated, with competing hypotheses involving bulk cerebrospinal fluid flow versus perivascular transport. Using multimodal in vivo imaging and computational modeling in mice, this study demonstrates that arterial pulsation drives bidirectional solute movement within the ...
Shiyong Li +9 more
wiley +1 more source
Towards a truly biomimetic olfactory microsystem: an artificial olfactory mucosa
IET Seminar on MEMS Sensors and Actuators, 2006 Today, the capability of the human olfactory system is still, in many ways, superior to that of the electronic nose. Although electronic noses are often compared with their biological counterpart, they neither mimic its neural architecture nor achieve its discriminating performance.
Covington, JA +4 more
openaire +4 more sources
Head &Neck, EarlyView.ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder +11 more
wiley +1 more source
Prion shedding from olfactory neurons into nasal secretions. [PDF]
PLoS Pathogens, 2010 This study investigated the role of prion infection of the olfactory mucosa in the shedding of prion infectivity into nasal secretions. Prion infection with the HY strain of the transmissible mink encephalopathy (TME) agent resulted in a prominent ...
Richard A Bessen +7 more
doaj +1 more source
Unique Features of Nasal Airway and Airflow Improvement Post‐Dupilumab: A Computational Cohort Study
The Laryngoscope, EarlyView.The impact of dupilumab on nasal airway patency and airflow is not uniform. It is more pronounced in the middle and superior, but not inferior meatus. These unique regional changes significantly correlate with and potentially drive the improvement in patient symptoms.
Ahmad Odeh +12 more
wiley +1 more source
Isolation of human adult olfactory sphere cells as a cell source of neural progenitors
Stem Cell Research, 2015 Olfactory stem cells are generated from olfactory mucosa. Various culture conditions generate olfactory stem cells that differ according to species and developmental stage and have different progenitor or stem cell characteristics. Olfactory spheres (OSs)
Yu-ichiro Ohnishi +10 more
doaj +1 more source