Methods of olfactory ensheathing cell harvesting from the olfactory mucosa in dogs. [PDF]
PLoS ONE, 2019 Olfactory ensheathing cells are thought to support regeneration and remyelination of damaged axons when transplanted into spinal cord injuries. Following transplantation, improved locomotion has been detected in many laboratory models and in dogs with ...
Daisuke Ito +6 more
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Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612. [PDF]
J Nanobiotechnology, 2021 Mesenchymal stem cells (MSCs) play important roles in tissue repair and regeneration, such as the induction of angiogenesis, particularly under hypoxic conditions. However, the molecular mechanisms underlying hypoxic MSC activation remain largely unknown.
Ge L +9 more
europepmc +2 more sources
Gene and protein expression profiles of olfactory ensheathing cells from olfactory bulb versus olfactory mucosa. [PDF]
Neural Regen Res, 2022 Olfactory ensheathing cells (OECs) from the olfactory bulb (OB) and the olfactory mucosa (OM) have the capacity to repair nerve injury. However, the difference in the therapeutic effect between OB-derived OECs and OM-derived OECs remains unclear. In this
Lan YX +6 more
europepmc +2 more sources
Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. [PDF]
PLoS ONE, 2017 Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfactory nerves. We have previously demonstrated that the cribriform plate is permissive for T cells and monocytes and that viruses can enter the bulb upon ...
Carolin Piotrowski +7 more
doaj +3 more sources
Human Olfactory Mucosa Stem Cells Delivery Using a Collagen Hydrogel: As a Potential Candidate for Bone Tissue Engineering. [PDF]
Materials (Basel), 2021 For bone tissue engineering, stem cell-based therapy has become a promising option. Recently, cell transplantation supported by polymeric carriers has been increasingly evaluated. Herein, we encapsulated human olfactory ectomesenchymal stem cells (OE-MSC)
Simorgh S +9 more
europepmc +2 more sources
Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories. [PDF]
Mol Neurodegener, 2021 Detection of the pathological and disease-associated alpha-synuclein (αSynD) in the brain is required to formulate the definitive diagnosis of multiple system atrophy (MSA) and Parkinson’s disease (PD).
Bargar C +18 more
europepmc +2 more sources
Oxidative Chemical Stressors Alter the Physiological State of the Nasal Olfactory Mucosa of Atlantic Salmon. [PDF]
Antioxidants (Basel), 2020 The olfactory organs of fish have vital functions for chemosensory and defence. Though there have been some ground-breaking discoveries of their involvement in immunity against pathogens in recent years, little is known about how they respond to non ...
Lazado CC +5 more
europepmc +2 more sources
Endothelin increases the proliferation of rat olfactory mucosa cells
Neural Regeneration Research, 2020 The olfactory mucosa holds olfactory sensory neurons directly in contact with an aggressive environment. In order to maintain its integrity, it is one of the few neural zones which are continuously renewed during the whole animal life.
Bertrand Bryche +5 more
doaj +2 more sources
Optimized Electrode Placements for Non-invasive Electrical Stimulation of the Olfactory Bulb and Olfactory Mucosa. [PDF]
Front Neurosci, 2020 The olfactory system is known to be dysfunctional in the early stages of Parkinson’s disease (PD) and Alzheimer’s disease (AD). It is also shown that intact olfactory function can be a key role player for regaining consciousness after brain injuries ...
Cakmak YO, Nazim K, Thomas C, Datta A.
europepmc +2 more sources
Environmental toxicants-induced immune responses in the olfactory mucosa
Frontiers in Immunology, 2016 Olfactory sensory neurons (OSNs) are the receptor cells for the sense of smell. Although cell bodies are located in the olfactory mucosa of the nasal cavity, OSN axons directly project to the olfactory bulb that is a component of the central nervous ...
Fumiaki Imamura, Sanae Hasegawa-Ishii
doaj +2 more sources