Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. [PDF]
PLoS ONE, 2017 Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfactory nerves. We have previously demonstrated that the cribriform plate is permissive for T cells and monocytes and that viruses can enter the bulb upon ...
Carolin Piotrowski +7 more
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Fibroblasts isolated from human middle turbinate mucosa cause neural progenitor cells to differentiate into glial lineage cells. [PDF]
PLoS ONE, 2013 Transplantation of olfactory ensheathing cells (OECs) is a potential therapy for repair of spinal cord injury (SCI). Autologous transplantation of OECs has been reported in clinical trials.
Xingjia Wu +2 more
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Lesion of the olfactory epithelium accelerates prion neuroinvasion and disease onset when prion replication is restricted to neurons. [PDF]
PLoS ONE, 2015 Natural prion diseases of ruminants are moderately contagious and while the gastrointestinal tract is the primary site of prion agent entry, other mucosae may be entry sites in a subset of infections.
Jenna Crowell +2 more
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Lipocalin 15 in the olfactory mucus is a biomarker for Bowman’s gland activity
Scientific Reports, 2022 Olfactory mucus contributes to the specific functions of the olfactory mucosa, but the composition and source of mucus proteins have not been fully elucidated.
Chiori Ijichi +13 more
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Drug-induced Parkinson's disease modulates protein kinase A and Olfactory Marker Protein in the mouse olfactory bulb [PDF]
, 2017 Background Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs.
Caretta, Antonio, Mucignat, Carla
core +2 more sources
Frontiers in Immunology, 2023 IntroductionThe Coronavirus Disease 2019 (COVID-19) is mainly a respiratory syndrome that can affect multiple organ systems, causing a variety of symptoms.
Lorenzo Lupi +16 more
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Microvillous cells in the olfactory epithelium express elements of the solitary chemosensory cell transduction signaling cascade. [PDF]
PLoS ONE, 2018 The nasal cavity hosts an array of chemoresponsive cells, including the extended olfactory system and several other cells involved in detection of and responses to irritants.
Federica Genovese, Marco Tizzano
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Disease-specific, neurosphere-derived cells as models for brain disorders [PDF]
, 2010 There is a pressing need for patient-derived cell models of brain diseases that are relevant and robust enough to produce the large quantities of cells required for molecular and functional analyses.
Abrahamsen, G. +29 more
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Isolating Globose Basal Stem Cells from Albino Wistar Rats Using a Highly Specific Monoclonal Antibody [PDF]
Journal of Clinical and Diagnostic Research, 2013 Introduction: Olfactory mucosa which is situated in the roof of the nasal cavity possesses an extremely peculiar and exceptional type of pluripotent stem cells called Globose Basal Cells (GBCs) which help in lifelong regeneration of the olfactory ...
Avinash Thakur +3 more
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Use of platelet rich plasma in persistent olfactory dysfunction after COVID-19: a prospective study
Revista Portuguesa Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, 2023 Introduction: A promising technique to treat persistent olfactory impairment has recently been explored: platelet rich plasma (PRP) injection into the olfactory mucosa.
Francisco Alves de Sousa +8 more
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