Results 31 to 40 of about 393,252 (329)

TDP-43 seeding activity in the olfactory mucosa of patients with amyotrophic lateral sclerosis. [PDF]

Mol Neurodegener
Vizziello M, Dellarole IL, Ciullini A, Pascuzzo R, Lombardo A, Bellandi F, Celauro L, Battipaglia C, Ciusani E, Rizzo A, Catania M, Devigili G, Della Seta SA, Margiotta V, Consonni M, Faltracco V, Tiraboschi P, Riva N, Portaleone SMS, Zanusso G, Legname G, Lauria G, Dalla Bella E, Moda F.   +23 more
europepmc   +2 more sources

Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy. [PDF]

Kaohsiung J Med Sci
Wang J, Peng J, Gao L, He J, Lin L, Li JM, Xia Y.   +6 more
europepmc   +2 more sources

Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells - Implications for Alzheimer's disease. [PDF]

Redox Biol
Mussalo L, Lampinen R, Avesani S, Závodná T, Krejčík Z, Kalapudas J, Penttilä E, Löppönen H, Koivisto AM, Malm T, Topinka J, Giugno R, Jalava P, Kanninen KM.   +13 more
europepmc   +2 more sources

Olfactory mucosa-mesenchymal stem cells with overexpressed Nrf2 modulate angiogenesis and exert anti-inflammation effect in an in vitro traumatic brain injury model. [PDF]

Eur J Med Res
Chen Z, Zhang C, Fang Y, Zhang H, Luo J, Miao C, Li J, Peng J, Qiu Y, Xia Y, Luo Q.   +10 more
europepmc   +2 more sources

Detection of TDP‐43 seeding activity in the olfactory mucosa from patients with frontotemporal dementia

Alzheimer's & Dementia, 2023
We assessed TAR DNA‐binding protein 43 (TDP‐43) seeding activity and aggregates detection in olfactory mucosa of patients with frontotemporal lobar degeneration with TDP‐43‐immunoreactive pathology (FTLD‐TDP) by TDP‐43 seeding amplification assay (TDP43 ...
E. Fontana, M. Bongianni, A. Benussi, Erika Bronzato, Carlo Scialò, Luca Sacchetto, A. Cagnin, Santina Castriciano, E. Buratti, Fabrizio Gardoni, Maria Italia, Alberto Schreiber, Chiara Ferracin, M. Fiorini, Kathy L Newell, Laura Cracco, H. Garringer, M. P. Cecchini, M. Polymenidou, Alessandro Padovani, Salvatore Monaco, G. Legname, B. Ghetti, B. Borroni, G. Zanusso   +24 more
semanticscholar   +1 more source

Alpha-synuclein seeds in olfactory mucosa of patients with isolated REM sleep behaviour disorder.

Brain : a journal of neurology, 2021
Isolated REM sleep behaviour disorder (RBD) is an early-stage α-synucleinopathy in most, if not all, affected subjects. Detection of pathological α-synuclein in peripheral tissues of patients with isolated RBD may identify those progressing to Parkinson ...
A. Stefani, Á. Iranzo, E. Holzknecht, D. Perra, M. Bongianni, C. Gaig, B. Heim, M. Serradell, Luca Sacchetto, Alicia Garrido, S. Capaldi, A. Sánchez-Gómez, M. P. Cecchini, S. Mariotto, S. Ferrari, M. Fiorini, J. Schmutzhard, P. Cocchiara, I. Vilaseca, Lorenzo Brozzetti, S. Monaco, M. José Martí, K. Seppi, E. Tolosa, J. Santamaria, B. Högl, W. Poewe, G. Zanusso   +27 more
semanticscholar   +1 more source

Isolation and Characterization of Cat Olfactory Ecto-Mesenchymal Stem Cells

Animals, 2022
The olfactory mucosa contains olfactory ecto-mesenchymal stem cells (OE-MSCs) which show stemness features, multipotency capabilities, and have a therapeutic potential. The OE-MSCs have already been collected and isolated from various mammals. The aim of
Marie-Laure Mollichella, Violaine Mechin, Dany Royer, Patrick Pageat, Pietro Asproni   +4 more
doaj   +1 more source

Impact of Copper Nanoparticles and Copper Ions on Transcripts Involved in Neural Repair Mechanisms in Rainbow Trout Olfactory Mucosa

Archives of Environmental Contamination and Toxicology, 2022
Olfactory mucosa is well known for its lifelong ability for regeneration. Regeneration of neurons and regrowth of severed axons are the most common neural repair mechanisms in olfactory mucosa.
P. Razmara, G. Pyle
semanticscholar   +1 more source

Fibroblasts isolated from human middle turbinate mucosa cause neural progenitor cells to differentiate into glial lineage cells. [PDF]

PLoS ONE, 2013
Transplantation of olfactory ensheathing cells (OECs) is a potential therapy for repair of spinal cord injury (SCI). Autologous transplantation of OECs has been reported in clinical trials.
Xingjia Wu, William E Bolger, Juanita J Anders   +2 more
doaj   +1 more source

Lesion of the olfactory epithelium accelerates prion neuroinvasion and disease onset when prion replication is restricted to neurons. [PDF]

PLoS ONE, 2015
Natural prion diseases of ruminants are moderately contagious and while the gastrointestinal tract is the primary site of prion agent entry, other mucosae may be entry sites in a subset of infections.
Jenna Crowell, James A Wiley, Richard A Bessen   +2 more
doaj   +1 more source