Results 61 to 70 of about 393,252 (329)

Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium. [PDF]

open access: yesPLoS ONE, 2012
P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP1) are membrane transporter proteins which function as efflux pumps at cell membranes and are considered to exert a protective function against the entry of xenobiotics.
Adrien Molinas   +2 more
doaj   +1 more source

Olfactory evaluation in obstructive sleep apnoea patients [PDF]

open access: yes, 2018
The sense of smell has a high impact on the quality of life. The aim of the present study was to investigate olfactory dysfunction in patients with obstructive sleep apnoea syndrome (OSAS) and correlate the severity of disease with olfactory dysfunction.
ANGELETTI, DILETTA   +7 more
core   +1 more source

Effect of formaldehyde inhalation on rabbit nasal mucosa: a light microscopic study—an animal model for inhalational irritants on nasal mucosa

open access: yesThe Egyptian Journal of Otolaryngology, 2021
Background Formaldehyde is associated with many adverse health effects and is classified as a human carcinogen. Formaldehyde is highly water-soluble and readily absorbed and metabolized by the respiratory mucosa upon inhalation.
Wael Mohamed Adel AbdelKafy   +4 more
doaj   +1 more source

Office‐based olfactory mucosa biopsies [PDF]

open access: yesInternational Forum of Allergy & Rhinology, 2016
BackgroundRequests from researchers for olfactory mucosal biopsies are increasing as a result of advances in the fields of neuroscience and stem cell biology. Published studies report variable rates of success in obtaining true olfactory tissue, often below 50%.
E. Holbrook, Lina Rebeiz, J. Schwob
semanticscholar   +4 more sources

Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]

open access: yes, 1993
The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer   +50 more
core   +1 more source

Antiviral Functions of Type I and Type III Interferons in the Olfactory Epithelium

open access: yesBiomolecules, 2023
The olfactory neuroepithelium (OE) is one of the few neuronal tissues where environmental pathogens can gain direct access. Despite this vulnerable arrangement, little is known about the protective mechanisms in the OE to prevent viral infection and its ...
Ahmad Zedan   +6 more
doaj   +1 more source

Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats [PDF]

open access: yes, 2003
The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Couet, William   +5 more
core   +1 more source

HISTOCHEMICAL STUDIES OF THE OLFACTORY MUCOSA OF THE RABBIT [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1955
1. Tests of the olfactory mucosa of rabbits by five different methods indicate that cholinesterase is probably not present in any of the cells of this tissue. 2. Alkaline phosphatase and phosphamidase were not found in the olfactory receptors. 3. Acid phosphatase and sulfhydryl groups were found to be present in the receptors, and the presence of ...
Betty J. Burkhardt, Harry C. Ehrmantraut
openaire   +3 more sources

The Potential Therapeutic Applications of Olfactory Ensheathing Cells in Regenerative Medicine

open access: yesCell Transplantation, 2014
Olfactory ensheathing cells (OECs) are unique glia cells restricted to the primary olfactory system including the olfactory mucosa, olfactory nerve, and the outer nerve layer of the olfactory bulb.
Ruey-Hwang Chou   +5 more
doaj   +1 more source

Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer’s Disease Patients

open access: yesCells, 2022
Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity. Olfactory dysfunction manifests early in several neurodegenerative disorders including Alzheimer’s disease, however, disease-related alterations to the olfactory ...
Riikka Lampinen   +20 more
doaj   +1 more source

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