Results 61 to 70 of about 31,173 (261)

Olfactory mucosa immunostaining v1

open access: yes, 2023
This protocol describes the immunostaining of olfactory mucosa cells after cocnentrating and depositing a monolayer of the cell suspension onto a slide. For the preparation of the olfactory mucosa suspension refer to protocol "Olfactory mucosa sampling and processing" : dx.doi.org/10.17504/protocols.io.14egn2b86g5d/v1
openaire   +1 more source

ELECTRON MICROSCOPIC OBSERVATIONS OF THE OLFACTORY MUCOSA AND OLFACTORY NERVE [PDF]

open access: yesThe Journal of Cell Biology, 1957
The olfactory receptor cell is characterized by a distal process (the dendrite) which terminates in the olfactory passage as the olfactory rod. The olfactory rod is provided with numerous cilia which are similar in structure to those seen in other tissues. The central processes of the bipolar cell constitute the fila olfactoria.
openaire   +2 more sources

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

A Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics

open access: yesAdvanced Science, EarlyView.
Biodegradable materials are gaining increasing attention in soft robotics and electronics due to their environmental friendliness, showing great potential for sustainability. In this review, the classification of biodegradable materials, their applications in the field of soft robotics and electronics, as well as the challenges and future prospects ...
Yizhu Xie   +8 more
wiley   +1 more source

Squamous and Respiratory Metaplasia After Olfactory Mucosal Resection

open access: yesFrontiers in Neuroscience, 2021
Resection of the olfactory mucosa (OM) is sometimes unavoidable during surgery; however, it is not known whether the OM can completely recover thereafter.
Eri Mori   +11 more
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

open access: yesAdvanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Could Cells from Your Nose Fix Your Heart? Transplantation of Olfactory Stem Cells in a Rat Model of Cardiac Infarction

open access: yesThe Scientific World Journal, 2010
This study examines the hypothesis that multipotent olfactory mucosal stem cells could provide a basis for the development of autologous cell transplant therapy for the treatment of heart attack.
Cameron McDonald   +3 more
doaj   +1 more source

Prion shedding from olfactory neurons into nasal secretions. [PDF]

open access: yesPLoS Pathogens, 2010
This study investigated the role of prion infection of the olfactory mucosa in the shedding of prion infectivity into nasal secretions. Prion infection with the HY strain of the transmissible mink encephalopathy (TME) agent resulted in a prominent ...
Richard A Bessen   +7 more
doaj   +1 more source

Anatomic Diagram as a Novel Assessment Strategy for Subclinical Local Residual Disease in Sinonasal Squamous Cell Carcinoma and Intestinal‐type Adenocarcinoma

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Objective In the last two decades, transnasal endoscopic surgery (TES) has become pivotal in the management of sinonasal tumors. This approach involves a multiblock tumor resection, adding complexity to the interpretation of surgical margins after pathological examination.
Piergiorgio Gaudioso   +14 more
wiley   +1 more source

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