Results 241 to 250 of about 133,718 (290)

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

Clinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna, Christina Morgenstern, Katharina Poglitsch, Tamara Arnoldner, Katharina Gangl, Tina J. Bartosik, Nicholas J. Campion, Aldine Tu, Victoria Stanek, Sven Schneider, Christine Bangert   +10 more
wiley   +1 more source

Beyond olfaction: New insights into human odorant binding proteins. [PDF]

Protein Sci
Chen M, Lakbir S, Jeon M, Mazur V, Abeln S, Mouhib H.   +5 more
europepmc   +1 more source

Cost of parasite exposure depends on host ontogeny 寄生接觸的代價依賴於宿主發育階段

Ecological Entomology, EarlyView.
The cost of parasite exposure varies across host developmental stages, demonstrating that ontogeny influences the expression of non‐consumptive effects (NCEs). Mite exposure resulted in consumptive effects in fly eggs and NCEs in early‐stage pupae; mite longevity was comparable when provisioned with pupae or water but increased when provisioned with ...
Lisa R. MacLeod, Connor L. MacPherson, Lien T. Luong   +2 more
wiley   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR-Dependent Translational Control of Synaptic Proteins. [PDF]

Adv Sci (Weinh)
Ren P, Cao R, Ye X, Pang W, Bi Q, Huang M, Zhou Q, Ye D, Xiang W, Xiao L.   +9 more
europepmc   +1 more source

Colour Polymorphism in Coconut Crabs Is Under Relaxed Selection From Conspecifics?

Ethology, EarlyView.
Coconut crabs are either red or blue irrespective of age or sex, are nocturnal and have very few predators. This experimental study shows that they do not use conspecific's colour but do use relative size to settle competitive interactions over food in the wild.
Tim Caro
wiley   +1 more source

Olfactory inputs to appetite neurons in the hypothalamus. [PDF]

Proc Natl Acad Sci U S A
Kuang D, Hanchate NK, Lee CY, Heck A, Ye X, Erdenebileg M, Mehta C, Hassan MM, Setty M, Buck LB.   +9 more
europepmc   +1 more source

Multiple cis‐regulatory elements collaborate to control mdka expression in telencephalic neural stem cells of adult zebrafish during constitutive and regenerative neurogenesis

The FEBS Journal, EarlyView.
midkine‐a (mdka), a pan‐injury response gene in vertebrates, is precisely regulated in the zebrafish telencephalon by a modular cis‐regulatory architecture. This control ensures proper expression during development, adult brain homeostasis, and regeneration.
Jincan Chen, Masanari Takamiya, Agnes Hendriks, Tanja Beil, Csilla Várnai, Nicolas Diotel, Sepand Rastegar   +6 more
wiley   +1 more source

Inhaled hinoki cypress essential oil improves saliva secretion and swallowing function in older adults with dysphagia: a randomized crossover study. [PDF]

Environ Health Prev Med
Aoyagi Y, Furuya R, Kawasaki M, Takenouchi M, Ohashi M, Li Q.   +5 more
europepmc   +1 more source

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source