Results 41 to 50 of about 133,718 (290)
The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer. [PDF]
Activating transcription factor 5 (ATF5) is a cellular prosurvival transcription factor within the basic leucine zipper (bZip) family that is involved in cellular differentiation and promotes cellular adaptation to stress.
Angelastro, James M, Sears, Thomas K
core +2 more sources
Molecular mechanisms of neurogenic aging in the adult mouse subventricular zone [PDF]
In the adult rodent brain, the continuous production of new neurons by neural stem/progenitor cells (NSPCs) residing in specialized neurogenic niches and their subsequent integration into pre-existing cerebral circuitries supports odour discrimination ...
Biagioni, Stefano +4 more
core +1 more source
Olfactory event-related potentials in a functionally anosmic patient with arrested hydrocephalus
Hydrocephalus is one of the lesser known causes of central olfactory loss. The pathogenesis of hydrocephalus involves the olfactory bulbs or tracts, and more rarely, other frontotemporal cortical regions.
Fabrizia Caminiti +5 more
doaj +1 more source
Before the onset of motor symptoms, Parkinson’s disease (PD) involves dysfunction of the anterior olfactory nucleus and olfactory bulb, causing olfactory disturbance, commonly resulting in hyposmia in the early stages of PD.
Yiqing Wang +11 more
doaj +1 more source
Development of an ex vivo model for the study of cerebrovascular function utilizing isolated mouse olfactory artery [PDF]
OBJECTIVE: Cerebral vessels, such as intracerebral perforating arterioles isolated from rat brain, have been widely used as an ex vivo model to study the cerebrovascular function associated with cerebrovascular disorders and the therapeutic effects of ...
Dietrich, Hans H. +3 more
core +2 more sources
Circuit dynamics of the olfactory pathway during olfactory learning
The olfactory system plays crucial roles in perceiving and interacting with their surroundings. Previous studies have deciphered basic odor perceptions, but how information processing in the olfactory system is associated with learning and memory is poorly understood. In this review, we summarize recent studies on the anatomy and functional dynamics of
Yutian J. Zhang +6 more
openaire +5 more sources
Dual second-messenger pathways in olfactory transduction
Increasing evidence indicates that inositol phosphate as well as cyclic nucleotide signalling pathways mediate olfactory transduction. Both pathways can target multiple ion channel effectors, suggesting that olfactory receptor cells serve as more than simple selectivity filters and that they possibly represent the first stage of olfactory integration.
Whitney Laboratory, University of Florida Ocean Shore Boulevard, St Augustine, Florida 32086, USA. ( host institution ) +2 more
openaire +3 more sources
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji +7 more
wiley +1 more source
Background/Objectives: Olfaction is in many ways the least understood sensory modality. Its organization and connectivity are still under debate. The aim of this study was to investigate the anatomy of the olfactory system by using a cadaver fiber ...
Anton Stenwall +5 more
doaj +1 more source
Neural regulation of fear based on olfactory, visual and auditory sensory systems [PDF]
Fear is a ubiquitous emotion that is crucial to the survival and development of humans and animals. Mammals perceive potential dangers through various sensory systems, thereby defending against or avoiding dangers.
Zhu Yimo
doaj +1 more source

