Results 41 to 50 of about 133,718 (290)

The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer. [PDF]

open access: yes, 2017
Activating transcription factor 5 (ATF5) is a cellular prosurvival transcription factor within the basic leucine zipper (bZip) family that is involved in cellular differentiation and promotes cellular adaptation to stress.
Angelastro, James M, Sears, Thomas K
core   +2 more sources

Molecular mechanisms of neurogenic aging in the adult mouse subventricular zone [PDF]

open access: yes, 2019
In the adult rodent brain, the continuous production of new neurons by neural stem/progenitor cells (NSPCs) residing in specialized neurogenic niches and their subsequent integration into pre-existing cerebral circuitries supports odour discrimination ...
Biagioni, Stefano   +4 more
core   +1 more source

Olfactory event-related potentials in a functionally anosmic patient with arrested hydrocephalus

open access: yesJournal of International Medical Research, 2019
Hydrocephalus is one of the lesser known causes of central olfactory loss. The pathogenesis of hydrocephalus involves the olfactory bulbs or tracts, and more rarely, other frontotemporal cortical regions.
Fabrizia Caminiti   +5 more
doaj   +1 more source

Functional Covariance Connectivity of Gray and White Matter in Olfactory-Related Brain Regions in Parkinson’s Disease

open access: yesFrontiers in Neuroscience, 2022
Before the onset of motor symptoms, Parkinson’s disease (PD) involves dysfunction of the anterior olfactory nucleus and olfactory bulb, causing olfactory disturbance, commonly resulting in hyposmia in the early stages of PD.
Yiqing Wang   +11 more
doaj   +1 more source

Development of an ex vivo model for the study of cerebrovascular function utilizing isolated mouse olfactory artery [PDF]

open access: yes, 2015
OBJECTIVE: Cerebral vessels, such as intracerebral perforating arterioles isolated from rat brain, have been widely used as an ex vivo model to study the cerebrovascular function associated with cerebrovascular disorders and the therapeutic effects of ...
Dietrich, Hans H.   +3 more
core   +2 more sources

Circuit dynamics of the olfactory pathway during olfactory learning

open access: yesFrontiers in Neural Circuits
The olfactory system plays crucial roles in perceiving and interacting with their surroundings. Previous studies have deciphered basic odor perceptions, but how information processing in the olfactory system is associated with learning and memory is poorly understood. In this review, we summarize recent studies on the anatomy and functional dynamics of
Yutian J. Zhang   +6 more
openaire   +5 more sources

Dual second-messenger pathways in olfactory transduction

open access: yesCurrent Opinion in Neurobiology, 1995
Increasing evidence indicates that inositol phosphate as well as cyclic nucleotide signalling pathways mediate olfactory transduction. Both pathways can target multiple ion channel effectors, suggesting that olfactory receptor cells serve as more than simple selectivity filters and that they possibly represent the first stage of olfactory integration.
Whitney Laboratory, University of Florida Ocean Shore Boulevard, St Augustine, Florida 32086, USA. ( host institution )   +2 more
openaire   +3 more sources

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

The Bulb, the Brain and the Being: New Insights into Olfactory System Anatomy, Organization and Connectivity

open access: yesBrain Sciences
Background/Objectives: Olfaction is in many ways the least understood sensory modality. Its organization and connectivity are still under debate. The aim of this study was to investigate the anatomy of the olfactory system by using a cadaver fiber ...
Anton Stenwall   +5 more
doaj   +1 more source

Neural regulation of fear based on olfactory, visual and auditory sensory systems [PDF]

open access: yesBIO Web of Conferences
Fear is a ubiquitous emotion that is crucial to the survival and development of humans and animals. Mammals perceive potential dangers through various sensory systems, thereby defending against or avoiding dangers.
Zhu Yimo
doaj   +1 more source

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