Results 231 to 240 of about 2,821,537 (354)

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

High-speed odor transduction and pulse tracking by insect olfactory receptor neurons

Proceedings of the National Academy of Sciences of the United States of America, 2014
P. Szyszka, P. Szyszka, R. C. Gerkin, C. Galizia, B. Smith   +4 more
semanticscholar   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Morphological specializations of mosquito CO₂-sensing olfactory receptor neurons. [PDF]

Proc Natl Acad Sci U S A
Charara S, Choy J, Cauwenberghs K, Vijayakumar P, Ng R, Kim KY, Weng SC, Akbari OS, Ellisman MH, Rifkin SA, Su CY.   +10 more
europepmc   +1 more source

Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors.

Neuron, 2014
M. Shirasu, Keiichi Yoshikawa, Y. Takai, Ai Nakashima, Haruki Takeuchi, H. Sakano, K. Touhara   +6 more
semanticscholar   +1 more source

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo, Per Borghammer, Inas Elsayed, Jennifer G. Goldman, Yue Huang, Katja Lohmann, Per Svenningsson, Lorraine V. Kalia, Daniela Berg, Jeffrey H. Kordower, the MDS Scientific Issues Committee   +10 more
wiley   +1 more source

A Fully In Silico Protocol to Understand Olfactory Receptor-Odorant Interactions. [PDF]

ACS Omega
Berwal B, Saha P, Kumar R.
europepmc   +1 more source

Progression of Motor and Cognitive Functions in Isolated REM Sleep Behavior Disorder: A 7‐Year Prospective Matched Cohort Study

Movement Disorders, EarlyView.
Abstract Background Although clinical markers (eg, motor and cognitive impairment) in isolated rapid eye movement sleep behavior disorder (iRBD) are associated with faster phenoconversion, their longitudinal trajectory patterns (linear or nonlinear) remain unclear.
Li Zhou, Yaping Liu, Bei Huang, Jing Wang, Shi Tang, Yuhua Yang, Siyi Gong, Steven W.H. Chau, Joey W.Y. Chan, Mandy W.M. Yu, Jessie C.C. Tsang, Shirley Xin Li, Siu Ping Lam, Vincent C.T. Mok, Karen K.Y. Ma, Anne Y.Y. Chan, Jihui Zhang, Yun Kwok Wing   +17 more
wiley   +1 more source

Optimizing Odorants for Olfactory Training Based on Olfactory Receptor-Ligand Pair Analysis. [PDF]

Laryngoscope
Nishijima H, Holbrook EH, Schwob JE, Mori E, Kagoya R, Ogawa K, Horikiri K, Kondo K.   +7 more
europepmc   +1 more source

Healthy Dietary Patterns and Risk of Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Although healthy dietary patterns have been suggested to be associated with decreased Parkinson's disease (PD) risk, their protective role remains uncertain. Objective To examine associations between eight dietary patterns and PD risk in two United States (US) cohorts followed for up to 32 years.
Xiao Chen, Hui Chen, Peilu Wang, Michael A. Schwarzschild, Albert Y. Hung, Xiang Gao, Alberto Ascherio, Mario H. Flores‐Torres, Kjetil Bjornevik   +8 more
wiley   +1 more source