Results 81 to 90 of about 145,746 (359)

Co-regulation of a large and rapidly evolving repertoire of odorant receptor genes

BMC Neuroscience, 2007
The olfactory system meets niche- and species-specific demands by an accelerated evolution of its odorant receptor repertoires. In this review, we describe evolutionary processes that have shaped olfactory and vomeronasal receptor gene families in ...
Lane Robert P, Kambere Marijo B
doaj   +1 more source

The Odorant Receptor-Dependent Role of Olfactory Marker Protein in Olfactory Receptor Neurons [PDF]

The Journal of Neuroscience, 2016
Olfactory receptor neurons (ORNs) in the nasal cavity detect and transduce odorants into action potentials to be conveyed to the olfactory bulb. Odorants are delivered to ORNs via the inhaled air at breathing frequencies that can vary from 2 to 10 Hz in the mouse. Thus olfactory transduction should occur at sufficient speed such that it can accommodate
DIBATTISTA, Michele, Reisert, Johannes
openaire   +4 more sources

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Ultramicroscopic organization of the exterior olfactory organ in Anguilla vulgaris in relation to its spawning migration

Open Veterinary Journal
Background: Catadromous fishes have well developed elongate olfactory organs with numerous lamellae and different types of receptor neurons related to their breeding migration.
Sheren A. Al-Zahaby, Sahar S. Hassan, Eman H. Elsheikh   +2 more
doaj   +1 more source

Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons

Biology Open, 2013
Summary Kallmann's syndrome is caused by the failure of olfactory axons and gonadotropin-releasing hormone (GnRH) neurons to enter the embryonic forebrain, resulting in anosmia and sterility.
Perrine Barraud, James A. St John, C. Claus Stolt, Michael Wegner, Clare V. H. Baker   +4 more
doaj   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Resolving different presynaptic activity patterns within single olfactory glomeruli of Xenopus laevis larvae

Scientific Reports, 2021
Olfactory sensing is generally organized into groups of similarly sensing olfactory receptor neurons converging into their corresponding glomerulus, which is thought to behave as a uniform functional unit.
Rodi Topci, Mihai Alevra, Erik H. U. Rauf, Daniëlle de Jong-Bolm   +3 more
doaj   +1 more source

Olfaction in mosquitoes [PDF]

, 2007
Female mosquitoes are vectors of diseases, affecting both livestock and humans. The host-seeking and identification behaviors of mosquitoes are mediated mainly by olfactory cues. The peripheral olfactory organs of mosquitoes which perceive olfactory cues
Ghaninia, Majid
core  

Asymmetric ephaptic inhibition between compartmentalized olfactory receptor neurons. [PDF]

, 2019
In the Drosophila antenna, different subtypes of olfactory receptor neurons (ORNs) housed in the same sensory hair (sensillum) can inhibit each other non-synaptically.
Bushong, Eric A, Chiang, Ann-Shyn, Chu, Li-An, Ellisman, Mark H, Reingruber, Jürgen, Su, Chih-Ying, Tsang, Tin Ki, Zhang, Ye   +7 more
core   +3 more sources

In Situ Proliferating Peptide Nanoparticle Augments Multi‐Target Intervention of Secondary Brain Damage Following Subarachnoid Hemorrhage

Advanced Science, EarlyView.
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang, Peisen Yao, Fuxiang Chen, Shufa Zheng, Xuegang Niu, Haojie Wang, Yuanxiang Lin, Bin Gao, Dezhi Kang   +8 more
wiley   +1 more source