Results 121 to 130 of about 102,826 (347)

Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

eLife, 2017
The monogenic and monoallelic expression of only one out of >1000 mouse olfactory receptor (ORs) genes requires the formation of large heterochromatic chromatin domains that sequester the OR gene clusters. Within these domains, intergenic transcriptional enhancers evade heterochromatic silencing and converge into interchromosomal hubs that assemble ...
Kevin Monahan, Ira Schieren, Jonah Cheung, Alice Mumbey-Wafula, Edwin S Monuki, Stavros Lomvardas   +5 more
openaire   +6 more sources

Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits

Advanced Science, EarlyView.
Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu, Lan Pang, Wenqi Shi, Ting Feng, Zhi Dong, Yifeng Sheng, Sicong Zhou, Longtao Yu, Hao Guo, Ying Wang, Jiani Chen, Jianhua Huang   +11 more
wiley   +1 more source

Gain control in olfactory receptor neurons and the detection of temporal fluctuations in odor concentration. [PDF]

Front Physiol, 2023
Tichy H, Hellwig M.
europepmc   +1 more source

Insect olfactory neurons: receptors, development, and function

Current Opinion in Insect Science
Insects represent the most diverse group of animals in the world. While the olfactory systems of different species share general principles of organization, they also exhibit a wide range of structural and functional diversity. Scientists have gained tremendous insight into olfactory neural development and function, notably in Drosophila, but also in ...
openaire   +2 more sources

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis

Cell Reports, 2018
Summary: In sterile neuroinflammation, a pathological role is proposed for microglia, whereas in viral encephalitis, their function is not entirely clear. Many viruses exploit the odorant system and enter the CNS via the olfactory bulb (OB).
Chintan Chhatbar, Claudia N. Detje, Elena Grabski, Katharina Borst, Julia Spanier, Luca Ghita, David A. Elliott, Marta Joana Costa Jordão, Nora Mueller, James Sutton, Chittappen K. Prajeeth, Viktoria Gudi, Michael A. Klein, Marco Prinz, Frank Bradke, Martin Stangel, Ulrich Kalinke   +16 more
doaj   +1 more source

A comparison of responses from olfactory receptor neurons of Heliothis subflexa and Heliothis virescens to components of their sex pheromone [PDF]

, 2003
Thomas C. Baker, S Ochieng, Allard A. Cossé, S. G. Lee, J. L. Todd, Carmen Quero, Neil J. Vickers   +6 more
openalex   +1 more source

Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models

AGING MEDICINE, EarlyView.
CB1 receptor (CB1R) expression was significantly reduced in the hippocampus, medial frontal gyrus, and superior temporal gyrus of Alzheimer's patients. CB1R levels negatively correlated with amyloid‐β and tau pathology. In addition, CB1R expression was also reduced in the cortex of 5xFAD mice and in the hippocampus of Tg4‐42 mice.
Nike von Borcke, Amrei Vivian Purwien, Annik Steiert, Henrike Hasecke, Yvonne Bouter   +4 more
wiley   +1 more source

Olfactory receptor neurons generate multiple response motifs, increasing coding space dimensionality. [PDF]

Elife, 2023
Kim B, Haney S, Milan AP, Joshi S, Aldworth Z, Rulkov N, Kim AT, Bazhenov M, Stopfer MA.   +8 more
europepmc   +1 more source

Calcium Activates a Chloride Conductance Likely Involved in Olfactory Receptor Neuron Repolarization in the MothSpodoptera littoralis [PDF]

, 2010
Adeline Pézier, Marta Grauso, Adrien Acquistapace, Christelle Monsempès, Jean-Pierre Rospars, Philippe Lucas   +5 more
openalex   +1 more source