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Frontiers in Cellular Neuroscience, 2021 Previous studies suggested that the SARS-CoV-2 virus may gain access to the brain by using a route along the olfactory nerve. However, there is a general consensus that the obligatory virus entry receptor, angiotensin converting enzyme 2 (ACE2), is not ...
Katarzyna Bilinska +2 more
doaj +1 more source
Carbon dioxide and fruit odor transduction in Drosophila olfactory neurons. What controls their dynamic properties? [PDF]
, 2014 We measured frequency response functions between odorants and action potentials in two types of neurons in Drosophila antennal basiconic sensilla. CO2 was used to stimulate ab1C neurons, and the fruit odor ethyl butyrate was used to stimulate ab3A ...
French, Andrew S +3 more
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Odorant Responsiveness of Squid Olfactory Receptor Neurons [PDF]
The Anatomical Record, 2008 AbstractIn the olfactory organ of the squid, Lolliguncula brevis there are five morphological types of olfactory receptor neurons (ORNs). Previous work to characterize odor sensitivity of squid ORNs was performed on only two of the five types in dissociated primary cell cultures. Here, we sought to establish the odorant responsiveness of all five types.
Arie Sitthichai, Mobley +2 more
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Gain control network conditions in early sensory coding [PDF]
, 2013 Gain control is essential for the proper function of any sensory system. However, the precise mechanisms for achieving effective gain control in the brain are unknown.
A Couto +67 more
core +5 more sources
Biophysical mechanisms underlying olfactory receptor neuron dynamics [PDF]
Nature Neuroscience, 2011 The responses of olfactory receptor neurons (ORNs) to odors have complex dynamics. Using genetics and pharmacology, we found that these dynamics in Drosophila ORNs could be separated into sequential steps, corresponding to transduction and spike generation. Each of these steps contributed distinct dynamics.
Nagel, Katherine I., Wilson, Rachel I.
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Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb [PDF]
, 2007 The formation of precise stereotypic connections in sensory systems is critical for the ability to detect and process signals from the environment. In the olfactory system, olfactory sensory neurons (OSNs) project axons to spatially defined glomeruli ...
Andrews, W +4 more
core +1 more source
Frontiers in Cellular Neuroscience, 2017 Understanding the mechanisms involved in maintaining lifelong neurogenesis has a clear biological and clinical interest. In the present study, we performed olfactory nerve transection on larval Xenopus to induce severe damage to the olfactory circuitry ...
Sara J. Hawkins +13 more
doaj +1 more source
Hedonic taste in Drosophila revealed by olfactory receptors expressed in taste neurons. [PDF]
PLoS ONE, 2008 Taste and olfaction are each tuned to a unique set of chemicals in the outside world, and their corresponding sensory spaces are mapped in different areas in the brain.
Makoto Hiroi +2 more
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Drug-induced Parkinson's disease modulates protein kinase A and Olfactory Marker Protein in the mouse olfactory bulb [PDF]
, 2017 Background Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs.
Caretta, Antonio, Mucignat, Carla
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The Odorant Receptor-Dependent Role of Olfactory Marker Protein in Olfactory Receptor Neurons [PDF]
The Journal of Neuroscience, 2016 Olfactory receptor neurons (ORNs) in the nasal cavity detect and transduce odorants into action potentials to be conveyed to the olfactory bulb. Odorants are delivered to ORNs via the inhaled air at breathing frequencies that can vary from 2 to 10 Hz in the mouse. Thus olfactory transduction should occur at sufficient speed such that it can accommodate
DIBATTISTA, Michele, Reisert, Johannes
openaire +3 more sources