Results 51 to 60 of about 5,107 (150)

Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed, Victor Schwartz Hvingelby, Jose A. Pineda‐Pardo, Javier Blesa, Steffen Paschen, Anurag Tandon, Juho Joutsa, Andreas Nørgaard Glud   +7 more
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Autoradiographic localization of [3H]-Nisoxetine binding sites in the CNS of male and female Japanese quail

Journal of Basic and Applied Zoology, 2021
Background In the central nervous system of mammals, transporters localized on the presynaptic nerve terminals regulate the reuptake of neurotransmitters.
Shannon E. Eaton, James R. Pauly, Deann M. Hopkins, Chana K. Akins   +3 more
doaj   +1 more source

Optimized workflow for behavior-coupled fiber photometry experiment: improved data navigation and accessibility. [PDF]

Front Neurosci
Fiber photometry provides crucial insights into cell population activity underlying behavior. While numerous open-source data analysis tools exist, few offer an automated workflow that streamlines the analysis of fiber photometry data alongside ...
Athanassi A, François A, Bourinet E, Thevenet M, Mandairon N.   +4 more
europepmc   +2 more sources

Identification of BCL2L11 as a Candidate Gene for Hereditary Predisposition to Non‐Medullary Thyroid Cancer Using Familial Whole‐Exome‐Sequencing

Clinical Genetics, EarlyView.
Whole‐exome sequencing of five families with non‐medullary thyroid cancer revealed three candidate genes. Functional analyses confirmed BCL2L11 as a strong candidate gene for hereditary predisposition to non‐medullary thyroid cancer. ABSTRACT Familial non‐medullary thyroid cancer, defined as two or more affected first‐degree relatives, accounts for 3 ...
Duygu Abbasoglu, Mathis Lepage, Nicolas Sonnier, Sandrine Viala, Nancy Uhrhammer, Flora Ponelle‐Chachuat, Anne Cayre, Maud Privat, Mathias Cavaillé, Yannick Bidet   +9 more
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Novel Gene-Informed Regional Brain Targets for Clinical Screening for Major Depression. [PDF]

Neurol Int
Background/Objectives: Major Depression (MD) is a common disorder that has significant social and economic impacts. Approximately 30% of all MD patients are refractory to common treatments, representing a major obstacle to managing the impacts of ...
Odierna GL, Sharpley CF, Bitsika V, Evans ID, Vessey KA.   +4 more
europepmc   +2 more sources

Prognostic Value of Magnetic Resonance Imaging Defined Extent of Surgical Resection in Dogs With Intracranial Meningiomas

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Surgery is a common treatment for intracranial meningiomas in dogs, although the prognostic impact of the extent of resection (EOR) has not been systematically evaluated. This retrospective study identified prognostic factors associated with clinical outcomes in dogs that underwent surgery and early post‐operative magnetic resonance imaging ...
John H. Rossmeisl, Rell L. Parker, Richard L. Shinn, Josefa K. Garcia Mora, Thomas E. Cecere, Teresa Southard, John L. Robertson   +6 more
wiley   +1 more source

Transformation of valence signaling in a mouse striatopallidal circuit

eLife
The ways in which sensory stimuli acquire motivational valence through association with other stimuli is one of the simplest forms of learning. Although we have identified many brain nuclei that play various roles in reward processing, a significant gap ...
Donghyung Lee, Nathan Lau, Lillian Liu, Cory M Root   +3 more
doaj   +1 more source

Cytologic and Histologic Findings of Extrapleural Solitary Fibrous Tumor: Report of Two Cases

Diagnostic Cytopathology, Volume 54, Issue 2, Page E46-E53, February 2026.
ABSTRACT Solitary fibrous tumors (SFT) are a rare neoplasm of mesenchymal origin. SFT was previously described primarily in the pleura and meninges; however, extrapleural and extra‐meningeal SFT have been reported in almost every anatomic site and account for up to 40% of cases.
Michael Tyler, Katsiaryna Khatskevich, Chadi Hajar, Jack Yang, Hao Liu   +4 more
wiley   +1 more source