Results 81 to 90 of about 604 (162)

A cofactor‐promiscuous HMGR from the Lyme disease pathogen illuminates diversity in bacterial isoprenoid biosynthesis

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopentenyl pyrophosphate (IPP), the precursor to the peptidoglycan carrier lipid.
Isaac A. Paddy, Joshua McCausland, Madelyn Frazier, Poulami Chatterjee, Mekedlawit Setegne, Oliv Eidam, Christine Jacobs‐Wagner, Laura M. K. Dassama   +7 more
wiley   +1 more source

Natural variation in the atypical resistance gene Ptr confers broad‐spectrum neck blast resistance in rice

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Neck blast (NB), caused by Magnaporthe oryzae, infects rice (Oryza sativa L.) and reduces yield. Knowledge of NB resistance remains limited due to the lack of reliable resistance evaluation methods. Here, we applied a newly established neck injection method and performed a genome‐wide association study (GWAS) on 335 diverse accessions from the
Ian Paul Navea, Mohammad Abdul Monsur, Mary Jeanie Telebanco‐Yanoria, Dianne Gene De La Rosa, Sherry Lou Hechanova, Arvin Paul Tuaño, Christian Joseph Cumagun, Il‐Ryong Choi, Suresh Kadaru, Sung‐Ryul Kim, Bo Zhou, Van Schepler‐Luu   +11 more
wiley   +1 more source

Tectono‐Stratigraphic Evolution of a Shared Foreland Basin: A 3D Geomodel and Detrital Flux Reconstruction for the Pliocene‐Pleistocene of the Po‐Plain Basin (Northern Italy)

Basin Research, Volume 38, Issue 5, September‐October 2026.
The Plio‐Pleistocene succession of the Po Plain Basin was interpreted basin‐wide using seismic profiles and well data, identifying six major tectonic unconformities. Sediment volumes were calculated and decompacted to assess tectonic and climatic controls on basin infill, revealing a marked increase in detrital flux after 1.5 Ma, coincident with the ...
Barrera Daniel, Toscani Giovanni, Catellani Daniele, Meda Marco, Fantoni Roberto, Di Giulio Andrea   +5 more
wiley   +1 more source

Chromosome-specific painting provides insights into the karyotype evolutionary direction and trajectory in the genus <i>Medicago</i>. [PDF]

Hortic Res
Wang W, Zhu Y, Wu X, Guo Z, Zheng Q, Shi G, Li Y, Luo W, Wang F, Shen H, Zuo S, Xie Q, Li H, Meng Z.   +13 more
europepmc   +1 more source

Decoding IGLL5 Mutation‐Mediated BCR Signaling: A Novel Mechanism of CD8+ T Cell Exhaustion and Ocular MALT Lymphoma Progression

Advanced Science, Volume 13, Issue 44, 7 August 2026.
OAML harbors recurrent IGLL5 mutations that reinforce CD79A/CD79B‐associated BCR signaling. Mechanistic analysis of the S47G and A54G variants reveals induction of CXCL10/CXCL11, enhanced CD8+ T‐cell recruitment, and exhaustion‐associated dysfunction, supporting an immune‐tolerant niche.
Andi Zhao, Haoyu Wei, Chenyu Zhou, Xinping Sun, Shuyan Da, Haiyu Liu, Zijin Wang, Hui Zhu, Shiya Shen, Qing Shao, Qi Gong, Hu Liu, Xuejuan Chen   +12 more
wiley   +1 more source

Chromosome-specific oligo-painting provides insights into the cytogenetic basis of karyotypic stasis in paleo-allotetraploid <i>Cucurbita</i>. [PDF]

Hortic Res
Zhao Q, Bai Y, Wang Y, Cheng C, Yu X, Lou Q, Chen J.   +6 more
europepmc   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, Volume 13, Issue 43, 3 August 2026.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Thriving or Withering? Plant Molecular Cytogenetics in the First Quarter of the 21st Century. [PDF]

Int J Mol Sci
Wolny E, Mur LAJ, Ohmido N, Yin Z, Wang K, Hasterok R.   +5 more
europepmc   +1 more source

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, Volume 13, Issue 46, 17 August 2026.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

A molecular cytogenetic perspective on chromosome biology and crop improvement. [PDF]

Plant Genome
Gill BS.
europepmc   +1 more source