Results 1 to 10 of about 18,169 (233)

Matched oligoclonal bands: Diagnostic utility and clinical characteristics [PDF]

Annals of Clinical and Translational Neurology
Objective To describe patient clinical characteristics associated with matched oligoclonal bands (OCB). Methods A retrospective review at the University of Utah examined patients with matched OCB from 2015 to 2020.
Yoji Hoshina, Justin R. Abbatemarco, Stefanie J. Rodenbeck, Jason T. Poon, Suzanne C. Liu, M. Mateo Paz Soldan, John E. Greenlee, John W. Rose, Lisa K. Peterson, Lisa Johnson, Alen Delic, Tammy L. Smith, Stacey L. Clardy   +12 more
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Oligoclonal Bands in Multiple System Atrophy: Case Report and Proposed Mechanisms of Immunogenicity [PDF]

Frontiers in Neuroscience, 2022
Multiple System Atrophy (MSA) is a neurodegenerative disease with heterogeneous manifestations and is therefore difficult to diagnose definitively. Because of this, oftentimes an extensive workup for mimickers is undertaken. We herein report a case where
Lee E. Neilson, Lee E. Neilson, Christopher Hollen, Christopher Hollen, Amie Hiller, Amie Hiller, Lindsey Wooliscroft, Lindsey Wooliscroft   +7 more
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The Diagnostic Utility of Oligoclonal Bands in Multiple Sclerosis: A Time-Course Analysis [PDF]

Biomedicines
Background: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). Oligoclonal bands (OCBs) in cerebrospinal fluid (CSF) are a hallmark of MS and reflect intrathecal IgG synthesis and inflammation.
Raffaella Candeloro, Caterina Ferri, Michele Laudisi, Eleonora Baldi, Maura Pugliatti, Massimiliano Castellazzi   +5 more
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Evidence of Oligoclonal Bands Does Not Exclude Non-Inflammatory Neurological Diseases [PDF]

Diagnostics, 2020
Cerebrospinal fluid analysis is an essential part of the diagnostic workup in various neurological disorders. Evidence of an intrathecal immunoglobulin synthesis, as demonstrated by Reiber’s diagram or the more sensitive oligoclonal bands (OCB), are ...
Katharina Pannewitz-Makaj, Ulrich Wurster, Konstantin Fritz Jendretzky, Stefan Gingele, Kurt-Wolfram Sühs, Martin Stangel, Thomas Skripuletz, Philipp Schwenkenbecher   +7 more
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Cerebrospinal fluid‐specific oligoclonal bands in dogs with idiopathic epilepsy [PDF]

Journal of Veterinary Internal Medicine
Background In dogs with idiopathic epilepsy (IE), 33% develop resistance to conventional anti‐seizure medication (ASM) despite adequate treatment. In human medicine, an immune‐mediated etiology is suspected in a subset of ASM‐resistant patients with ...
Junwei Föhr, Julia K. Prümmer, Arianna Maiolini, Eliane Marti, Ilijas Jelcic, Beatriz Vidondo, Mario Ziegler, Andrea Bathen‐Nöthen, Andrea Tipold, Holger A. Volk, Veronika M. Stein   +10 more
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Concordance rate between oligoclonal bands and the Kappa index in patients with suspected multiple sclerosis (MS) [PDF]

Arquivos de Neuro-Psiquiatria
Background Oligoclonal bands (OCBs) and Kappa free light chains (FLCs) in the cerebrospinal fluid (CSF) are sensitive markers of intrathecal immunoglobulin (Ig)G synthesis in patients with multiple sclerosis.
Renan Barros Domingues, Márcio Vega dos Santos, Daiane Salomão, Carlos Senne   +3 more
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CSF oligoclonal bands in neurological diseases besides CNS inflammatory demyelinating disorders [PDF]

BMJ Neurology Open
Objective To understand the distribution characteristics and clinical significance of cerebrospinal fluid (CSF) oligoclonal bands (OCBs) in different nervous system diseases besides typical central nervous system (CNS) inflammatory demyelinating ...
Feng Gao, Jing Guo, Ran Liu, Yan Yao, Jingru Ren, Jianchun Wang, Hongjun Hao   +6 more
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Cerebrospinal fluid oligoclonal bands in Neuroborreliosis are specific for Borrelia burgdorferi. [PDF]

PLoS ONE, 2020
BackgroundCerebrospinal fluid (CSF) oligoclonal bands (OCB) occur in chronic or post-acute phase of inflammatory diseases of the central nervous system.ObjectiveTo determine whether CSF OCB in patients with neuroborreliosis (NB) are specific for borrelia
Klaus Berek, Harald Hegen, Michael Auer, Anne Zinganell, Franziska Di Pauli, Florian Deisenhammer   +5 more
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Elevated Kappa Index in the Absence of Cerebrospinal Fluid IgG Oligoclonal Bands: Contribution of Intrathecal IgM and IgA Synthesis [PDF]

Biomolecules
The kappa index is a well-established marker of intrathecal synthesis (IS) of immunoglobulin (Ig). Routinely used for diagnostic aims, IgG IS, which can be assessed quantitatively (ad hoc formulas) or qualitatively (oligoclonal bands, OCBs), may fail in ...
Krzysztof Smolik, Roberta Bedin, Patrizia Natali, Martina Cardi, Diego Franciotta, Anna Maria Simone, Paolo Immovilli, Mario Santangelo, Matteo Gastaldi, Giulia De Napoli, Francesca Vitetta, Diana Ferraro   +11 more
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Kappa Free Light Chains in Cerebrospinal Fluid in Inflammatory and Non-Inflammatory Neurological Diseases

Brain Sciences, 2022
Background: Oligoclonal bands represent intrathecal immunoglobulin G (IgG) synthesis and play an important role in the diagnosis of multiple sclerosis (MS).
Franz Felix Konen, Philipp Schwenkenbecher, Konstantin Fritz Jendretzky, Stefan Gingele, Torsten Witte, Kurt-Wolfram Sühs, Matthias Grothe, Malte Johannes Hannich, Marie Süße, Thomas Skripuletz   +9 more
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