Between-Laboratory Variability in Oligoclonal IgG Band Numbering
The respective patterns of cerebrospinal fluid (CSF)-restricted oligoclonal IgG bands (OCBs) and assessment of their similarity in serum and CSF are important laboratory tools for evaluating immune-mediated inflammation of the central nervous system. OCB detection is the diagnostic laboratory tool of choice for multiple sclerosis (MS), in the initial ...
FRANCIOTTA D, AVOLIO C, LOLLI, FRANCESCO
openaire +2 more sources
A 50 year old with a rapid neuropsychiatric deterioration and choreaform movements [PDF]
A 50-year-old man presented acutely to the hospital with behavioural disturbance, choreiform movements and profound nihilistic delusions. He reported recent drug and alcohol abuse, and also apparent involvement in several recent criminal activities, for ...
Campbell, Stewart +3 more
core +1 more source
Familial haemophagocytic lymphohistiocytosis (FHL) is a rare, inherited granzyme–perforin system defect that predisposes individuals to haemophagocytic lymphohistiocytosis. This article presents two original case reports of FHL type 2, along with a comprehensive literature review. Together, these elements aim to enhance the current understanding of FHL
Nicolas Perrard +12 more
wiley +1 more source
Coincident onset of multiple sclerosis and herpes simplex virus 1 encephalitis. a case report [PDF]
Background: Along with vitamin D, smoking, body mass index and others, Epstein Barr virus, other herpesviruses and human endogenous retroviruses represent plausible environmental risk factors for multiple sclerosis.
Buscarinu, M. C. +7 more
core +2 more sources
A Case of Aseptic Meningitis Presenting With Widespread Non‐Dermatomal Neuropathic Pain
ABSTRACT Aseptic meningitis occasionally causes neuropathic pain in a dermatomal distribution, but widespread non‐dermatomal pain is extremely rare. We report a case of a 62‐year‐old man with ulcerative colitis who developed neuropathic pain involving the head, trunk, and limbs.
Jun Komoda
wiley +1 more source
Evidence of active demyelination during early stage of HIV-1 lnfection
The central nervous system is considered an early target for the human immunodeticiency virus type 1 (HIV-1). Serum and cerebrospinal fluid (CSF) from 20 HIV positive patients, including 14 with AIDS-dementia complex (CDC stage IV) and 6 asymptomatic ...
Alex Taranto Guterrez +2 more
doaj
Prolonged Anti‐Zic4 Antibody–Positive Cerebellar Degeneration Following COVID‐19 Infection
Serial MRI and SPECT revealed progressive cerebellar atrophy and worsening hypoperfusion over 2 years, despite partial clinical stabilization. These findings highlight radiological progression that exceeds symptom severity in post‐COVID anti‐Zic4 antibody–associated cerebellar degeneration.
Risa Suzuki‐Yamamoto +6 more
wiley +1 more source
Background Idiopathic intracranial hypertension (IIH) is a neurological disorder of unknown pathophysiology with many proposed theories that involve CSF dynamics but recently, involvement of inflammatory and autoimmune processes has been postulated ...
Mohamed S. El-Tamawy +5 more
doaj +1 more source
Quantification of intraocular interferon-gamma and IgG in cataract and diabetes [PDF]
We applied the machine learning procedure to the analysis of serum and aqueous humor albumin, IgG and interferon-gamma patterns. The data were analyzed with respect to the cataract, type of diabetes, retinopathy and blood-aqueous humor barrier damage ...
Biserka Pokrić +5 more
core +1 more source
A staged approach with vincristine, adriamycin, and dexamethasone followed by bortezomib, thalidomide, and dexamethasone before autologous hematopoietic stem cell transplantation in the treatment of newly diagnosed multiple myeloma [PDF]
Bortezomib-based regimens have significant activities in multiple myeloma (MM). In this study, we tested the efficacy of a total therapy with a staged approach, where newly diagnosed MM patients received vincristine/adriamycin/dexamethsone (VAD).
C. S. Chim +7 more
core +1 more source

