Results 111 to 120 of about 18,346 (233)
Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci +5 more
wiley +1 more source
Coincident onset of multiple sclerosis and herpes simplex virus 1 encephalitis. a case report [PDF]
Background: Along with vitamin D, smoking, body mass index and others, Epstein Barr virus, other herpesviruses and human endogenous retroviruses represent plausible environmental risk factors for multiple sclerosis.
Buscarinu, M. C. +7 more
core +2 more sources
Between-Laboratory Variability in Oligoclonal IgG Band Numbering
The respective patterns of cerebrospinal fluid (CSF)-restricted oligoclonal IgG bands (OCBs) and assessment of their similarity in serum and CSF are important laboratory tools for evaluating immune-mediated inflammation of the central nervous system. OCB detection is the diagnostic laboratory tool of choice for multiple sclerosis (MS), in the initial ...
FRANCIOTTA D, AVOLIO C, LOLLI, FRANCESCO
openaire +2 more sources
Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan +11 more
wiley +1 more source
Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes [PDF]
Prognostic molecular biomarkers for the conversion of clinically isolated syndrome (CIS) to multiple sclerosis (MS) are lacking. In a prospective longitudinal study of 813 individuals with CIS, Cantó et al.
Arrambide, Georgina +41 more
core
Influence of Quadrato Motor Training on Salivary proNGF and proBDNF [PDF]
Previous studies demonstrated exercise-induced modulation of neurotrophins, such as Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF).
Ben-Soussan, Tal D. +4 more
core +2 more sources
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson +12 more
wiley +1 more source
Immunology of multiple sclerosis [PDF]
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) leading to demyelination, axonal damage, and progressive neurologic disability.
A. Ascherio +52 more
core +1 more source
Development of CAR Exosomes Targeting FAP for the Treatment of Intrauterine Adhesion
ABSTRACT Engineered extracellular vesicles (EVs) have emerged as promising cell‐free platforms for immunomodulation and tissue repair. In this study, we generated EVs derived from chimeric antigen receptor (CAR) T cells targeting fibroblast activation protein (FAP) and investigated their biological and therapeutic functions.
Wenyan Fu +8 more
wiley +1 more source

