Results 11 to 20 of about 18,169 (233)
Oligoclonal bands: a laboratory diagnosis of subacute sclerosing panencephalitis (SSPE)
Journal of Infection in Developing Countries, 2022 The oligoclonal band indicates presence of antibodies specific to the disease, possibly due to the activation of certain clones of B lymphocytes. This intrathecal immunoglobin synthesis can be persistent for months to years, for example, in respons to ...
Weny Rinawati, July Kumalawati
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New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab
Frontiers in Neurology, 2020 Overview: We assessed the role of age and disease activity as new factors contributing to establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis patients treated with natalizumab in 36 University Hospitals in Europe.
Inmaculada Toboso +60 more
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Seronegative neurobrucellosis—do we need new neurobrucellosis criteria?
International Journal of Infectious Diseases, 2021 Neurobrucellosis presents in various clinical forms and should always be considered in neurological patients in highly endemic areas such as the Mediterranean basin.
Vassilis E. Papadopoulos +6 more
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Oligoclonal bands in multiple sclerosis
Neurology, 1985 Although oligoclonal banding is a characteristic feature of MS spinal fluid, some patients do not show this abnormality. Four of 18 consecutive patients with autopsy-proven MS had no oligoclonal bands (OB) in CSF during life or at postmortem. Patients with OB had numerous plasma cells in meninges and plaques (confirmed in sections stained for ...
Farrell, M +5 more
+7 more sources
Brain and Behavior, 2021 Background An association has been found between the presence of lipid‐specific oligoclonal IgM bands (LS‐OCMB) in cerebrospinal fluid and a more severe clinical multiple sclerosis course.
Clàudia Coll‐Martinez +11 more
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Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]
, 2006 It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko +3 more
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Fluids and Barriers of the CNS, 2012 Background Oligoclonal IgG bands in cerebrospinal fluid that are absent in serum indicate intrathecal IgG synthesis and are a sensitive marker of CNS inflammatory diseases, in particular multiple sclerosis.
Zeman David +5 more
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Cerebrospinal Fluid Analysis in Multiple Sclerosis Diagnosis: An Update [PDF]
, 2019 Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS) with brain neurodegeneration. MS patients present heterogeneous clinical manifestations in which both genetic and environmental factors are involved ...
Bruna Lo Sasso +4 more
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Biomedical Papers, 2015 Aims: To compare the sensitivity and specificity of CSF-restricted oligoclonal IgG and free light chains as markers of multiple sclerosis and other inflammatory neurological diseases.
David Zeman +6 more
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BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset [PDF]
, 2017 Background B lymphocytes are thought to play a relevant role in multiple sclerosis (MS) pathology. The in vivo analysis of intrathecally produced B cell-related cytokines may help to clarify the mechanisms of B cell recruitment and ...
Ermani, M. +11 more
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