Brain MRI in patients with multiple sclerosis with oligoclonal cerebrospinal fluid bands [PDF]
Locally produced oligoclonal IgG bands (OCB) are present in the cerebrospinal fluid (CSF) of 95% patients with multiple sclerosis (MS)[2,3]. The most sensitive method for the detection of OCB is isoelectric focusing (IEF) [1].
Mesaroš Šarlota +3 more
doaj +1 more source
A CPH-Like Picture in Two Patients with an Orbitocavernous Sinus Syndrome [PDF]
Two patients with retroorbital pain syndromes with or without paresis of cranial nerves developed weeks after ipsilateral headache resembling chronic paroxysmal hemicrania (CPH) but without autonomic features.
A Straube +5 more
core +1 more source
Antibodies in multiple sclerosis oligoclonal bands target debris [PDF]
IgG oligoclonal bands (OCB) are detected in the cerebrospinal fluid (CSF) of more than 90% of multiple sclerosis (MS) patients and are considered the immunological hallmark that supports MS diagnosis. OCB are not unique to MS but are also observed in chronic CNS infections, where they target their causative agents (1⇓–3).
Ryan C, Winger, Scott S, Zamvil
openaire +2 more sources
K Index in cerebrospinal fluid: a valid tool in multiple sclerosis diagnosis [PDF]
Detection of oligoclonal IgG bands in cerebrospinal fluid by isoelectrocfocusing and immunodetection is the current gold standard to detect an inflammatory process in the central nervous system.
Bernardini S +5 more
core +1 more source
Prognostic Factors of MS Conversion in Optic Neuritis
Investigators from Children’s Hospital Aschaffenburg, Germany; University of Manchester, Manchester, United Kingdom; University Children’s Hospital Tübingen, Tübingen, Germany; and other international centers studied prognostic factors in optic neuritis.
Marytery Fajardo, Jennifer P Rubin
doaj +1 more source
The MRZ reaction in primary progressive multiple sclerosis [PDF]
BACKGROUND: The MRZ reaction (MRZR), composed of the three antibody indices (AI) against measles, rubella and varicella zoster virus and found positive in the majority of relapsing-remitting multiple sclerosis (RRMS) patients, is absent in other ...
Benjamin Berger +5 more
core +1 more source
"AN ESTIMATION OF OLIGOCLONAL BANDS IN PATIENTS WITH MULTIPLE SCLEROSIS" [PDF]
Oligoclonal bands (OCB) can be detected in a significant percentage (90%) of patients with multiple sclerosis (MS), however, a much lower percentage has been reported in some studies, mainly from oriental countries.
M. H. Harirchian +2 more
doaj +2 more sources
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Serum Oligoclonal Immunoglobulin Bands in Cirrhotic Patients
Am J ...
Kalambokis, G. +3 more
openaire +2 more sources
Gene rearrangements in bone marrow cells of patients with acute myelogenous leukemia [PDF]
At diagnosis, clonal gene rearrangement probes {[}retinoic acid receptor (RAR)-alpha, major breakpoint cluster region (M-bcr), immunoglobulin (Ig)-JH, T cell receptor (TcR)-beta, myeloid lymphoid leukemia (MLL) or cytokine genes (GM-CSF, G-CSF, IL-3 ...
Braun, S. +5 more
core +1 more source

