Results 61 to 70 of about 18,169 (233)

Cerebrospinal Fluid IgM and Oligoclonal IgG Bands in Multiple Sclerosis: A Meta-Analysis of Prevalence and Prognosis

open access: yesBrain Sciences, 2021
The presence of intrathecal IgM synthesis (ITMS) has been associated with an aggressive multiple sclerosis (MS) clinical course. In the present systematic review, we aimed at assessing the prevalence of ITMS among different MS phenotypes.
Mattia Fonderico   +10 more
doaj   +1 more source

Associations of HLA DRB1 alleles with IgG oligoclonal bands and their influence on multiple sclerosis course and disability status

open access: yesMedicina, 2016
Background and aim: Oligoclonal bands (OCB) may be associated with the genes of HLA complex, which allows to consider the possible interaction of genetic and immunological factors and its importance in the development and progression of multiple ...
Renata Balnytė   +5 more
doaj   +1 more source

Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients. [PDF]

open access: yesPLoS ONE, 2013
to explore the association between genetic markers and Oligoclonal Bands (OCB) in the Cerebro Spinal Fluid (CSF) of Italian Multiple Sclerosis patients.We genotyped 1115 Italian patients for HLA-DRB1*15 and HLA-A*02. In a subset of 925 patients we tested
Maurizio A Leone   +24 more
doaj   +1 more source

Clinically isolated syndrome: Diagnosis and risk of developing clinically definite multiple sclerosis

open access: yesNeurología (English Edition), 2023
Introduction: In most cases, multiple sclerosis (MS) initially presents as clinically isolated syndrome (CIS). Differentiating CIS from other acute or subacute neurological diseases and estimating the risk of progression to clinically definite MS is ...
J. López-Gómez   +3 more
doaj   +1 more source

Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at elapse of childhood precursor-B–ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual disease [PDF]

open access: yes, 2002
Immunoglobulin (Ig) and T-cell receptor (TCR) gene rearrangements are excellent patient-specific polymerase chain reaction (PCR) targets for detection of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL), but they might be unstable ...
Brinkhof, B. (Bas)   +5 more
core   +3 more sources

Predicting epilepsy after new onset refractory status epilepticus due to autoimmune encephalitis: The DAME score

open access: yesEpilepsia, EarlyView.
Abstract Objective This study aimed to identify risk factors and develop a predictive scoring system for autoimmune‐associated epilepsy in subjects with autoimmune encephalitis presenting with new onset refractory status epilepticus (NORSE). Methods This retrospective, multicenter, cohort study included subjects who presented with NORSE at the onset of
Simona Lattanzi   +50 more
wiley   +1 more source

Oligoclonal M bands unveil occult inflammation in multiple sclerosis

open access: yesMultiple Sclerosis and Related Disorders, 2022
Recent works demonstrate that patients with multiple sclerosis (pwMS) and oligoclonal M bands (OCMB) in cerebrospinal fluid (CSF) are at higher risk of conversion to secondary progressive course, suggesting a distinct pathophysiology pathway in these patients.To analyze the relationship of serum neurofilament light chain (s-NFL) in absence of ...
Bonaventura Casanova   +11 more
openaire   +3 more sources

Juvenile Mycosis Fungoides: A Multicenter Retrospective Italian Study

open access: yesJEADV Clinical Practice, EarlyView.
This multicenter retrospective study included 29 juvenile mycosis fungoides (JMF) patients from five Italian centres with confirmed histopathological diagnosis. most often presents with hypopigmented/classic variants and CD8+ phenotype. Early‐onset cases ( < 14 years) show better long‐term outcomes.
Andrea Michelerio   +8 more
wiley   +1 more source

Neurosyphilis presenting with papillitis [PDF]

open access: yes, 2017
Syphilis is one of the oldest described infectious diseases in the world and is caused by the spirochete bacterium Treponema pallidum[1]. Although now a rare disease, incidence is increasing with the number of diagnoses of the disease rising in England ...
Cooper, Sarah   +2 more
core   +4 more sources

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