History of Innate Immunity in Neurodegenerative Disorders [PDF]
The foundations of innate immunity in neurodegenerative disorders were first laid by Del Rio Hortega (1919). He identified and named microglia, recognizing them as cells of mesodermal origin.
Edith G. McGeer, Patrick L. McGeer
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Editorial: Non-neuronal cell heterogeneity in the nervous system during health and disease
Greg J. Duncan+6 more
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Oligodendroglia: new players in amyotrophic lateral sclerosis [PDF]
The contribution of glial cells to the neuropathology and phenotype of amyotrophic lateral sclerosis (ALS) has become a focus for basic and translational research. Whereas astrocytes and microglia are studied in great detail, the contribution of oligodendrocytes has been relatively neglected.
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PD-1 regulates neural damage in oligodendroglia-induced inflammation.
We investigated the impact of immune regulatory mechanisms involved in the modulation of the recently presented, CD8+ lymphocyte mediated immune response in a mouse model of oligodendropathy-induced inflammation (PLPtg-mutants). The focus was on the role
Antje Kroner+7 more
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Induction of annexin-1 at transcriptional and posttranscriptional level in rat brain by methylprednisolone and the 21-aminosteroid U74389F [PDF]
Jan Kornelis de Cock ...
Go, KG+5 more
core
Oligodendroglia development in cell culture as monitored with a monoclonal antibody [PDF]
JM Collins, NW Seeds
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Yuan Zhou,1 Ning Li,2 Lin Zhu,3 Yixing Lin,3 Huilin Cheng1 1Department of Neurosurgery, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Jiangsu, China; 2Department of Surgery, Li Ka Shing Faculty of Medicine, The ...
Zhou Y, Li N, Zhu L, Lin Y, Cheng H
doaj
Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation. [PDF]
Disruption of the blood-brain barrier (BBB) is critical to initiation and perpetuation of disease in multiple sclerosis (MS). We report an interaction between oligodendroglia and vasculature in MS that distinguishes human white matter injury from normal ...
Baranzini, Sergio E+9 more
core
Perturbed Interactions of Mutant Proteolipid Protein/DM20 with Cholesterol and Lipid Rafts in Oligodendroglia: Implications for Dysmyelination in Spastic Paraplegia [PDF]
Eva‐Maria Krämer‐Albers+4 more
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The Selective RNA-binding Protein Quaking I (QKI) Is Necessary and Sufficient for Promoting Oligodendroglia Differentiation [PDF]
Yuntao Chen+4 more
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