Results 21 to 30 of about 68,127 (203)
Rational Generation of Monoclonal Antibodies Selective for Pathogenic Forms of Alpha-Synuclein
Biomedicines, 2022 Misfolded toxic forms of alpha-synuclein (α-Syn) have been implicated in the pathogenesis of synucleinopathies, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA).
Ebrima Gibbs +12 more
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Molecules, 2019 Aggregation of amyloid β42 (Aβ42) is one of the hallmarks of Alzheimer’s disease (AD). There are numerous naturally occurring products that suppress the aggregation of Aβ42, but the underlying mechanisms remain to be elucidated ...
Kazuma Murakami, Kazuhiro Irie
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Molecules, 2020 The nitrous acid depolymerization of chitosan enables the synthesis of singular chitosan oligosaccharides (COS) since their reducing-end unit is composed of 2,5-anhydro-d-mannofuranose (amf).
Maxence Coudurier +6 more
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Oligomer Formation by Amyloid-β42 in a Membrane-Mimicking Environment in Alzheimer’s Disease
Molecules, 2022 The brains of Alzheimer’s disease (AD) patients contain numerous amyloid plaques that are diagnostic of the disease. The plaques are primarily composed of the amyloidogenic peptides proteins Aβ40 and Aβ42, which are derived by the processing of the ...
Terrone L. Rosenberry +3 more
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Foods, 2023 Plant fiber/plastic composites (PPCs) have been widely used in food contact materials (FCMs) for many benefits, such as their claimed better environmental footprint compared to conventional plastics.
Hong Zhang +4 more
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Molecules, 2022 Polyethylene terephthalate (PET) is one of the most widely used food contact materials due to its excellent mechanical properties and recyclability. Migration of substances from PET and assessment of compliance are usually determined by experimental ...
Verena N. Schreier +2 more
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Molecular weight dependent antistaphylococcal activities of oligomers/polymers synthesized from 3-aminopyridi [PDF]
Journal of the Serbian Chemical Society, 2010 The main aim of this study was to investigate the relationship between molecular weight and the antistaphylococcal activity of oligomers/polymers synthesized from 3-aminopyridine.
CAHIT AKGUL, MEHMET YILDIRIM
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Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation
Frontiers in Molecular Neuroscience, 2019 Alzheimer’s disease (AD) pathology is characterized by the aggregation of beta-amyloid (Aβ) and tau in the form of amyloid plaques and neurofibrillary tangles in the brain.
Woo Shik Shin +13 more
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Frontiers in Molecular Neuroscience, 2020 Tau is a predominantly neuronal protein that is normally bound to microtubules, where it acts to modulate neuronal and axonal stability. In humans, pathological forms of tau are implicated in a range of diseases that are collectively known as tauopathies.
Emily Hill +3 more
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Characterization of Proanthocyanidin Oligomers of Ephedra sinica
Molecules, 2017 Ephedra sinica, an important plant in Chinese traditional medicine, contains a complex mixture of proanthocyanidin oligomers as major constituents; however, only the minor components have been chemically characterized.
Joanna Orejola +3 more
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