Results 31 to 40 of about 92,702 (304)

Three Structural Features of Functional Food Components and Herbal Medicine with Amyloid β42 Anti-Aggregation Properties

open access: yesMolecules, 2019
Aggregation of amyloid β42 (Aβ42) is one of the hallmarks of Alzheimer’s disease (AD). There are numerous naturally occurring products that suppress the aggregation of Aβ42, but the underlying mechanisms remain to be elucidated ...
Kazuma Murakami, Kazuhiro Irie
doaj   +1 more source

Elucidation of Non-Intentionally Added Substances from Plant Fiber/Plastic Composites by UPLC-QTOF/MS

open access: yesFoods, 2023
Plant fiber/plastic composites (PPCs) have been widely used in food contact materials (FCMs) for many benefits, such as their claimed better environmental footprint compared to conventional plastics.
Hong Zhang   +4 more
doaj   +1 more source

Migration Modeling as a Valuable Tool for Exposure Assessment and Risk Characterization of Polyethylene Terephthalate Oligomers

open access: yesMolecules, 2022
Polyethylene terephthalate (PET) is one of the most widely used food contact materials due to its excellent mechanical properties and recyclability. Migration of substances from PET and assessment of compliance are usually determined by experimental ...
Verena N. Schreier   +2 more
doaj   +1 more source

Understanding the Pathophysiological Actions of Tau Oligomers: A Critical Review of Current Electrophysiological Approaches

open access: yesFrontiers in Molecular Neuroscience, 2020
Tau is a predominantly neuronal protein that is normally bound to microtubules, where it acts to modulate neuronal and axonal stability. In humans, pathological forms of tau are implicated in a range of diseases that are collectively known as tauopathies.
Emily Hill   +3 more
doaj   +1 more source

Molecular weight dependent antistaphylococcal activities of oligomers/polymers synthesized from 3-aminopyridi [PDF]

open access: yesJournal of the Serbian Chemical Society, 2010
The main aim of this study was to investigate the relationship between molecular weight and the antistaphylococcal activity of oligomers/polymers synthesized from 3-aminopyridine.
CAHIT AKGUL, MEHMET YILDIRIM
doaj  

Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation

open access: yesFrontiers in Molecular Neuroscience, 2019
Alzheimer’s disease (AD) pathology is characterized by the aggregation of beta-amyloid (Aβ) and tau in the form of amyloid plaques and neurofibrillary tangles in the brain.
Woo Shik Shin   +13 more
doaj   +1 more source

Characterization of Proanthocyanidin Oligomers of Ephedra sinica

open access: yesMolecules, 2017
Ephedra sinica, an important plant in Chinese traditional medicine, contains a complex mixture of proanthocyanidin oligomers as major constituents; however, only the minor components have been chemically characterized.
Joanna Orejola   +3 more
doaj   +1 more source

Relative GAPDH oligomer formation.

open access: yes, 2022
Absorbance maximums are reported for each of the peaks that correspond to the relative molecular weights for each oligomer. Tetramer, dimer, and monomer, illustrated by number of subunits as shown on the x-axis. (TIFF)
Naomi Ghebremichael (9578319)   +6 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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