Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling +6 more
wiley +1 more source
Implementation of the Vapor-Liquid Equilibrium On the Kinetic Model for the Oligomerization of Olefins. [PDF]
Cordero-Lanzac T +5 more
europepmc +1 more source
Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang +5 more
wiley +1 more source
The living coordination polymerization of norbornene is achieved using a nickel catalyst derived from Ni(cod)2 and 2,6‐dihydroxybenzoic acid with trityl borate as cocatalyst to produce poly(norbornene) with controllable molecular weights and narrow polydispersity.
Taidong Yao +5 more
wiley +1 more source
Avoiding Mitochondrial Apoptosis by the Bcl-2-Driven Bax Oligomerization on Membrane Surfaces. [PDF]
Ayscough SE +12 more
europepmc +1 more source
Performance of pyDock in 8th CAPRI: Energy‐Based Scoring Applied to Docking and AlphaFold Models
ABSTRACT The 8th CAPRI edition has shown a significant evolution in the field of protein–protein complex structure prediction. We have participated in all 11 targets proposed in this edition, involving domain‐domain, protein–protein, protein‐peptide, and protein‐DNA interactions, including homo‐ and hetero‐meric interfaces.
Luis Angel Rodríguez‐Lumbreras +5 more
wiley +1 more source
KCC2 phosphorylation dynamics relate to oligomerization during development and after spinal cord injury. [PDF]
Liabeuf S +4 more
europepmc +1 more source
The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria
ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham +3 more
wiley +1 more source
Decoding polyethylene formation in Cr/PNP catalyzed ethylene oligomerization <i>via</i> experimentally guided machine learning. [PDF]
Zhu Y +6 more
europepmc +1 more source
AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions
ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley +1 more source

