Results 221 to 230 of about 631,547 (339)

Addition of oligonucleotides to the 5′-terminus of DNA by T4 RNA ligase

open access: bronze, 1979
N. Patrick Higgins   +2 more
openalex   +1 more source

Highly Ordered DNA Framework Interface Enables Efficient Enzymatic Oligonucleotide Synthesis

open access: yesAdvanced Science, EarlyView.
Tetrahedral DNA nanostructures (TDN) ‐based nanoscopic interface provides ordered upright orientation and optimal spacing for initiator primers, enhancing enzyme accessibility in interfacial enzymatic oligonucleotide synthesis (EOS). Notably, efficient TDN‐based EOS is employed for DNA information storage by synthesizing a 60‐nucletide DNA fragment ...
Kunjie Li   +9 more
wiley   +1 more source

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

open access: yesAdvanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu   +14 more
wiley   +1 more source

Advanced Nanomaterial-Based Electrochemical Biosensing of Loop-Mediated Isothermal Amplification Products. [PDF]

open access: yesBiosensors (Basel)
Kuprešanin A   +12 more
europepmc   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

open access: yesAdvanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu   +13 more
wiley   +1 more source

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