Results 21 to 30 of about 635,743 (331)

DNA Data Storage

BioTech, 2023
The demand for data storage is growing at an unprecedented rate, and current methods are not sufficient to accommodate such rapid growth due to their cost, space requirements, and energy consumption.
Tomasz Buko, Nella Tuczko, Takao Ishikawa   +2 more
doaj   +1 more source

Identification of candidate regulatory sequences in mammalian 3' UTRs by statistical analysis of oligonucleotide distributions [PDF]

, 2007
3' untranslated regions (3' UTRs) contain binding sites for many regulatory elements, and in particular for microRNAs (miRNAs). The importance of miRNA-mediated post-transcriptional regulation has become increasingly clear in the last few years.
Caselle, Michele, Cora, Davide, Di Cunto, Ferdinando, Provero, Paolo   +3 more
core   +4 more sources

Polymer–Colloid Complexes Based on Cationic Imidazolium Amphiphile, Polyacrylic Acid and DNA Decamer

Molecules, 2021
The solution behavior and physicochemical characteristics of polymer–colloid complexes based on cationic imidazolium amphiphile with a dodecyl tail (IA-12) and polyacrylic acid (PAA) or DNA decamer (oligonucleotide) were evaluated using tensiometry ...
Darya A. Kuznetsova, Dinar R. Gabdrakhmanov, Denis M. Kuznetsov, Svetlana S. Lukashenko, Valery M. Zakharov, Anastasiia S. Sapunova, Syumbelya K. Amerhanova, Anna P. Lyubina, Alexandra D. Voloshina, Diana V. Salakhieva, Lucia Ya. Zakharova   +10 more
doaj   +1 more source

Rapid generation of chromosome-specific alphoid DNA probes using the polymerase chain reaction [PDF]

, 1992
Non-isotopic in situ hybridization of chromosome-specific alphoid DNA probes has become a potent tool in the study of numerical aberrations of specific human chromosomes at all stages of the cell cycle. In this paper, we describe approaches for the rapid
A Gnirke, AHN Hopman, AR Mitchell, C Huxley, C Lengauer, Christoph Lengauer, D Pinkel, ED Green, EW Jabs, HF Willard, HF Willard, HF Willard, HM Rosenberg, Ian Dunham, J Anastasi, J Meyne, JE Koch, JS Waye, JS Waye, JS Waye, L Manuelidis, L Manuelidis, M Klever, P Emmerich, PJ Poddighe, PR Langer, S Popp, T Cremer, T Cremer, T Cremer, T Imai, T Maniatis, Terry Featherstone, Thomas Cremer   +33 more
core   +1 more source

Enhancing the Therapeutic Delivery of Oligonucleotides by Chemical Modification and Nanoparticle Encapsulation

Molecules, 2017
Oligonucleotide (ON) drugs, including small interfering RNA (siRNA), microRNA (miRNA) and antisense oligonucleotides, are promising therapeutic agents.
Yating Sun, Yarong Zhao, Xiuting Zhao, Robert J. Lee, Lesheng Teng, Chenguang Zhou   +5 more
doaj   +1 more source

Sensitive Silver-Enhanced Microplate Apta-Enzyme Assay of Sb³⁺ Ions in Drinking and Natural Waters

Molecules, 2023
The toxic effects of antimony pose risks to human health. Therefore, simple analytical techniques for its widescale monitoring in water sources are in demand. In this study, a sensitive microplate apta-enzyme assay for Sb3+ detection was developed.
Nadezhda S. Komova, Kseniya V. Serebrennikova, Anna N. Berlina, Anatoly V. Zherdev, Boris B. Dzantiev   +4 more
doaj   +1 more source

Dendrimer Anion-Exchange Stationary Phase for Separation of Oligonucleotides

Molecules, 2022
Oligonucleotides are used in many research areas. Thus, there is a need for their successful separation methods. Ion-exchange chromatography is the most popular separation technique, but it has limitations for these compounds.
Sylwia Studzińska, Szymon Bocian, Anna Kilanowska, Bogusław Buszewski   +3 more
doaj   +1 more source

Potential Inherent Stimulation of the Innate Immune System by Nucleic Acid Aptamers and Possible Corrective Approaches

Pharmaceuticals, 2018
It is well known that unmethylated 2′-deoxycytidine-phosphate-2′-guanine (CpG) sequences alone or in longer DNA and RNA oligonucleotides can act like pathogen-associated molecular patterns (PAMPs) and trigger the innate immune response ...
John G. Bruno
doaj   +1 more source

Watching the hands of the Arabidopsis biological clock [PDF]

, 2001
Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic pathways were found to be coordinately ...
Davis, Seth J., Millar, A. J. (Andrew J.)   +1 more
core   +2 more sources

Rapid and accurate synthesis of TALE genes from synthetic oligonucleotides

BioTechniques, 2016
Custom synthesis of transcription activator-like effector (TALE) genes has relied upon plasmid libraries of pre-fabricated TALE-repeat monomers or oligomers.
Fenghua Wang, Hefei Zhang, Jingxia Gao, Fengjiao Chen, Sijie Chen, Cuizhen Zhang, Gang Peng   +6 more
doaj   +1 more source