Results 31 to 40 of about 506,562 (336)
Chromosome Painting Based on Bulked Oligonucleotides in Cotton
Frontiers in Plant Science, 2020 Chromosome painting is one of the key technologies in cytogenetic research, which can accurately identify chromosomes or chromosome regions. Oligonucleotide (oligo) probes designed based on genome sequences have both flexibility and specificity, which ...
Yuling Liu +7 more
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Molecular Chromophore-DNA Architectures With Fullerenes: Optical Properties and Solar Cells
Frontiers in Chemistry, 2021 Supramolecular chemistry allows the construction of complex molecular architectures and the design of collective photophysical properties. DNA is an attractive template to build such supramolecular architectures due to its helical structure, the defined ...
Sara Müller +7 more
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Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]
, 2008 Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Baranowski, Eric +4 more
core +1 more source
Molecules, 2017 Antisense oligonucleotides (ASOs) conjugated to triantennary N-acetyl galactosamine (GalNAc) ligands represent an emerging approach to antisense therapy. Our current generation of GalNAc-ASO conjugates link the GalNAc to the 5′-terminus of the ASO.
Isaiah Cedillo +5 more
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The legacy of mRNA engineering: A lineup of pioneers for the Nobel Prize
Molecular Therapy: Nucleic Acids, 2022 mRNA is like Hermes, delivering the genetic code to cellular construction sites, so it has long been of interest, but only to a small group of scientists, and only demonstrating its remarkable efficacy in coronavirus disease 2019 (COVID-19) vaccines ...
Miroslaw Janowski, Anna Andrzejewska
doaj
Watching the hands of the Arabidopsis biological clock [PDF]
, 2001 Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic pathways were found to be coordinately ...
Davis, Seth J. +1 more
core +2 more sources
Molecular Therapy: Nucleic Acids, 2023 Tumor suppressor genes (TSGs) are frequently downregulated in cancer, leading to dysregulation of the pathways that they control. The continuum model of tumor suppression suggests that even subtle changes in TSG expression, for example, driven by ...
Georgina L. Gregory, Ian M. Copple
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Molecules, 2017 Oligonucleotide (ON) drugs, including small interfering RNA (siRNA), microRNA (miRNA) and antisense oligonucleotides, are promising therapeutic agents.
Yating Sun +5 more
doaj +1 more source
Bind-n-Seq: high-throughput analysis of in vitro protein-DNA interactions using massively parallel sequencing. [PDF]
, 2009 Transcription factor-DNA interactions are some of the most important processes in biology because they directly control hereditary information. The targets of most transcription factor are unknown.
Korf, Ian +2 more
core +2 more sources
Locked nucleic acid: tighter is different [PDF]
, 2013 This viewpoint briefly reviews the impact of Locked Nucleic Acid (LNA) oligonucleotides, first described in a ChemComm paper in 1998. A number of unique applications in oligonucleotide biotechnology have been made possible by the high binding affinity ...
Watts, Jonathan
core +1 more source