Results 181 to 190 of about 23,719,178 (251)

Water‐Dispersible Ruthenium Nanocatalyst for Carbonyl Reduction With D2 or T2 in Aqueous Media

Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.
We report the synthesis and characterization of water‐dispersible ruthenium nanoparticles that catalyze the reductive deuteration and tritiation of carbonyl compounds in aqueous media, enabling efficient access to a broad range of isotopically labeled polar molecules, including cyclic peptides, antibody‐drug conjugate linkers, pegylated derivatives ...
Elisa Martinelli, Rafael Jiménez Rioboo, Remo Weck, Sophie Feuillastre, Luis M. Martínez‐Prieto, Grégory Pieters, Volker Derdau   +6 more
wiley   +2 more sources

A scalable, low-cost, sample hashing workflow for multiomic single-cell analysis using the Seq-Well S³ platform. [PDF]

Nat Protoc
Russo DD, Quinn SL, Kholod O, Elovitz MA, Lauffenburger DA, Sabeti P, Julg B, Edlow AG, Goods BA, Shalek AK, Triana S.   +10 more
europepmc   +1 more source

Design, evaluation, and validation of specific primers for accurate detection of VHS virus in rainbow trout (Oncorhynchus mykiss)

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract Accurate detection of Piscine novirhabdovirus (PNRV), also know as viral hemorrhagic septicemia virus (VHSV) in rainbow trout (Oncorhynchus mykiss) is essential for effective aquaculture disease management. This study developed strain‐inclusive primers targeting the conserved glycoprotein (G) gene using integrated bioinformatics approaches ...
Mohammad Kazem Momeni, Mohsen Mobini‐Dehkordi, Amin Nematollahi   +2 more
wiley   +1 more source

A Dual-Halogen Labeling Strategy to Detect and Quantify Double-Stranded RNAs Using NanoSIMS: A Proof-of-Concept Study. [PDF]

ACS Omega
Vicentini Q, Kurczy M, Estupiñán HY, Hekman D, Becquart C, Haag L, Andersson S, El-Andaloussi S, Dahlén A.   +8 more
europepmc   +1 more source

NMR‐Guided Fragment Screening Identifies Privileged Noncanonical Amino Acids for mRNA Display

ChemBioChem, Volume 27, Issue 18, 28 September 2026.
A strategy is reported to prescreen and prioritize noncanonical amino acids as fragments prior to their use in mRNA display peptide libraries. Using MDM2 as a target, two ncAAs that bind to the Trp binding pocket in MDM2 are found by protein‐observed NMR.
Abdul J. Castillo, Clark A. Jones, Alba C. Dutra, Chelsea A. Makovsky, Sandeep Lohan, Bipasana Shakya, Sara H. Walters, Brian Fuglestad, Matthew C. T. Hartman   +8 more
wiley   +1 more source

Noncanonical chromosomal-end-specific telomeric repeat arrays in naturally telomerase-negative yeasts. [PDF]

Nucleic Acids Res
Brejová B, Hodorová V, Lichancová H, Gafurov A, Bujna D, Brázdovič F, Červenák F, Petrík T, Hegedűsová E, Forgáčová Jakúbková M, Neboháčová M, Tomáška Ľ, Sipiczki M, Vinař T, Nosek J.   +14 more
europepmc   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, Volume 159, Issue 6, Page 1521-1534, 15 September 2026.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Quantification of disease-associated RNA tandem repeats by nanopore sensing. [PDF]

Nat Commun
Patiño-Guillén G, Pešović J, Panić M, Earle M, Ninković A, Petrușca S, Savić-Pavićević D, Keyser UF, Bošković F.   +8 more
europepmc   +1 more source

Toward Metabolomics Analyses With Combined Capillary Vibrating Sharp‐Edge Spray Ionization and Atmospheric Pressure Chemical Ionization

Rapid Communications in Mass Spectrometry, Volume 40, Issue 17, 15 September 2026.
ABSTRACT Rationale The varied properties of metabolomics components dictate the tools used in mass spectrometry (MS) characterization including the selection of the ionization source. However, the ionization of select compounds limits characterization efficiency.
Madison Pursell, Adefolake Ojanuga, Chandrima Banerjee, Ephraim Ezeigbo, Mohammad Rahman, Vikum K. Dewasurendra, Thomas B. Hughart, Matthew B. Johnson, Mst Nigar Sultana, Xiaoting Guo, Gabriel Alexander, Priya Patel, Peng Li, Justin Legleiter, Stephen J. Valentine   +14 more
wiley   +1 more source

Conformationally Constrained Phosphonate Backbone Linkages Enhance CpG Oligonucleotide Activation of Toll-Like Receptor 9. [PDF]

ACS Pharmacol Transl Sci
Kóšiová I, Štěpánek I, Šimák O, Kostov O, Petrová M, Páv O, Rejman D, Liboska R, Buděšínský M, Rosenbergová Š, Birkuš G, Rosenberg I.   +11 more
europepmc   +1 more source