Results 191 to 200 of about 708,274 (274)

Sequencing of d/l-DNA and XNA by Templated-Synthesis. [PDF]

J Am Chem Soc
Joshi S, Romanens P, Winssinger N.
europepmc   +1 more source

Lnc‐TPT1‐AS1/CBP/ATIC Axis Mediated Purine Metabolism Activation Promotes Breast Cancer Progression

Cancer Science, EarlyView.
Overexpression of TPT1‐AS1 could suppress the malignant phenotype and purine synthesis activation of breast cancer through competitive interaction with CBP, subsequently reducing the promoter H3K27ac signal and transcription of ATIC. Therefore, targeting the TPT1‐AS1/CBP/ATIC axis may provide a useful strategy for the treatment of patients with breast ...
Yiyun Zhang, Hanyu Zhang, Mingcui Li, Yanling Li, Zhuo‐Ran Wang, Weilun Cheng, Yansong Liu, Zhengbo Fang, Ang Zheng, Jingxuan Wang, Fei Ma   +10 more
wiley   +1 more source

From early methods for DNA diagnostics to genomes and epigenomes at high resolution during four decades - a personal perspective. [PDF]

Ups J Med Sci
Syvänen AC.
europepmc   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

Neuromuscular diseases: genomics-driven advances. [PDF]

Genomics Inform
Cho A.
europepmc   +1 more source

Gold Nanoprobes for Robust Colorimetric Detection of Nucleic Acid Sequences Related to Disease Diagnostics. [PDF]

Nanomaterials (Basel)
Enea M, Leite A, Franco R, Pereira E.
europepmc   +1 more source

A loop‐mediated isothermal amplification assay to detect insect‐associated Serratia spp. in the critically endangered insect Dryococelus australis

Insect Conservation and Diversity, EarlyView.
Inclusion of a novel sample cleanup step prior to extraction of bacterial DNA from insect frass enhanced rates of bacterial cell recovery and removed insect and plant cells. Development of a robust LAMP assay allowed detection of insect‐associated members of the Serratia marcescens complex in frass from live insects. Results from the LAMP assay applied
Nicholas P. Doidge, Joanne L. Allen, Rhys Bushell, Michael Lynch, Glenn F. Browning, Marc S. Marenda   +5 more
wiley   +1 more source

Tailoring Genomic Selection for Bos taurus indicus: A Comprehensive Review of SNP Arrays and Reference Genomes. [PDF]

Genes (Basel)
Ogunbawo AR, Mulim HA, Campos GS, Schinckel AP, Oliveira HR.   +4 more
europepmc   +1 more source

Molecular Identification of Agrilus anxius (Coleoptera: Buprestidae) Using a qPCR Assay With Locked Nucleic Acid (LNA) Probe

Journal of Applied Entomology, EarlyView.
ABSTRACT In the present study, a biomolecular diagnostic assay based on qPCR‐LNA (Locked Nucleic Acid) probes was developed for the identification of Agrilus anxius (Coleoptera: Buprestidae) from adult insects. The performance of the new protocol was also evaluated for indirect diagnosis of the insect's presence on artificially contaminated frass.
Domenico Rizzo, Francesco Pecori, Michela Moriconi, Claudia Gabriela Zubieta, Bruno Palmigiano, Linda Bartolini, Alice Downes, Chiara Ranaldi, Viola Papini, Nicola Luchi, Alberto Santini   +10 more
wiley   +1 more source