Results 221 to 230 of about 23,719,178 (251)

Navigating Human Astrocyte Differentiation: Direct and Rapid One‐Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development

Glia, Volume 74, Issue 9, September 2026.
One‐step protocol enabling direct differentiation of human iPSCs into functional astrocytes within 5 weeks. Validated in > 60 lines across 10 labs. iPSC‐astrocytes support robust neuronal network development in co‐culture. ABSTRACT Astrocytes play a pivotal role in neuronal network development.
Imke M. E. Schuurmans, Annika Mordelt, Marta Guevara‐Ferrer, Katrin Linda, Denise Duineveld, Sofia Puvogel, Marina P. Hommersom, Nicky Scheefhals, Lisa Rahm, Emma Dyke, Gijs‐Jan Scholten, Caroline Knorz, Carlos Gonzalez Jimenez, Noelle van Egmond, Astrid Oudakker, Chantal Bijnagte‐Schoenmaker, Hans van Bokhoven, Wei Wei, Samuel Hofmann, Sabine Jung‐Klawitter, Sandra Mojica‐Perez, Jack Parent, Lidia Carotenuto, Sarah Weckhuysen, Nadine Maas, Ype Elgersma, Eline van de Ven, Dirk Lefeber, Anita Lygeroudi, Helga E. de Vries, Luc Jordi, Magdalini Polymenidou, Teresa Mitchell‐Garcia, Iulia Dragan, Amalia Dolga, Lot D. de Witte, Clara D. M. van Karnebeek, James Ellis, Alejandro Garanto, Nael Nadif Kasri   +39 more
wiley   +1 more source

Optimizing nucleic acid delivery using PF14 peptide and lipid nanoparticle systems. [PDF]

Int J Pharm X
Daniele D, Hein ZM, Saher O, El-Serafi I.   +3 more
europepmc   +1 more source

3D ex vivo platform for high‐throughput immunotherapy screening in relapsed/refractory lymphoma patients

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Relapsed/refractory (R/R) B‐cell lymphomas (B‐NHL) remain incurable, with limited predictive biomarkers to guide immunotherapy. Preclinical platforms that faithfully preserve the immune context and the viability of patient samples are critically needed for relevant high‐throughput drug testing.
Fabien Gava, Paul Marcoux, Neus Serrat, Pauline Gravelle, Sonia Quertinmont, Marie Tosolini, Carla Faria, Juan G. Valero, Christina Schniederjohann, Cathy Quelen, Fanny Bouquet, Catia Fonseca, Sylvia Herter, Laura C. Deak, Ron McCord, Eugene Chiang, Peter‐Martin Bruch, Loïc Ysebaert, Patricia Pérez‐Galán, Camille Laurent, Christine Bezombes   +20 more
wiley   +1 more source

Harnessing endogenous CRISPR-Cas9 for inducible genetic engineering of <i>Apilactobacillus kunkeei</i>. [PDF]

Appl Environ Microbiol
Iyer MS, Hagström E, Näslund K, Andersson SGE.   +3 more
europepmc   +1 more source

Inherited microcytic anemias due to disorders of iron and heme metabolism: An updated clinical review

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Microcytic anemia is among the most common hematological abnormalities in clinical practice and is usually attributable to iron deficiency, thalassemia traits, or anemia of inflammation. A small but clinically important subset of patients, however, has inherited disorders of iron metabolism or heme synthesis presenting with persistent ...
Alexandros Makis, Ioanna Saougou, Eleftheria Hatzimichael   +2 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Dual-Component Surface-Enhanced Raman Scattering Detection of Tetracycline Based on Aptamer-Regulated Catalytic Switch. [PDF]

Ann N Y Acad Sci
Yang D, Chen L, Xu H, Yu Y, Xia Q, Chu PK, Hu T.   +6 more
europepmc   +1 more source

Benchmarking DNA barcode decoding strategies under high error rates. [PDF]

BMC Bioinformatics
Poma-Soto F, Van Droogenbroeck H, Soulliaert B, Giridhar M, Behr J, Sabzalipoor H, Somoza M, Mestdagh P, Vandesompele J.   +8 more
europepmc   +1 more source

Unraveling HBV Life Cycle by Fluorescent Microscopy Imaging. [PDF]

Viruses
Vega VS, Rat V, Seigneuret F, Eymieux S, Chouteau P, de Rocquigny H.   +5 more
europepmc   +1 more source

Intimate Interaction Between Nucleic Acid and Conjugated Polymers in Organic Electrochemical Transistors Enables Ultrasensitive Biomarker Detection. [PDF]

Adv Mater
Liu H, Wang N, Yang A, Song J, Li L, McCulloch I, Ka-Wai Law H, Yan F.   +7 more
europepmc   +1 more source