Results 41 to 50 of about 740,905 (276)
DNA microarrays in cancer diagnosis and prognosis [PDF]
Einstein (São Paulo), 2005 This review discusses recent advances in our understanding ofthe human genome and the application of derived technologies inthe medical area. It focuses on the use of DNA microarray fordiagnosis, prognosis, and therapeutic purposes in oncology, andthe ...
Oswaldo Keith Okamoto
doaj
BMC Genomics, 2006 Background DNA microarrays have proven powerful for functional genomics studies. Several technologies exist for the generation of whole-genome arrays.
Fairbanks Benjamin D +4 more
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Secondary structure in the target as a confounding factor in synthetic oligomer microarray design
BMC Genomics, 2005 Background Secondary structure in the target is a property not usually considered in software applications for design of optimal custom oligonucleotide probes.
Gibas Cynthia J +2 more
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NOTCH2 is neither rearranged nor mutated in t(1;19) positive oligodendrogliomas. [PDF]
PLoS ONE, 2009 The combined deletion of 1p and 19q chromosomal arms is frequent in oligodendrogliomas (OD) and has recently been shown to be mediated by an unbalanced t(1;19) translocation.
Magdalena Benetkiewicz +9 more
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Application of chicken microarrays for gene expression analysis in other avian species [PDF]
, 2009 BACKGROUND: With the threat of emerging infectious diseases such as avian influenza, whose natural hosts are thought to be a variety of wild water birds including duck, we are armed with very few genomic resources to investigate large scale immunological
Burggraaf, Simon +3 more
core +2 more sources
Thermodynamics of RNA/DNA hybridization in high density oligonucleotide microarrays [PDF]
Physica A 362, 433 (2006), 2004 We analyze a series of publicly available controlled experiments (Latin square) on Affymetrix high density oligonucleotide microarrays using a simple physical model of the hybridization process. We plot for each gene the signal intensity versus the hybridization free energy of RNA/DNA duplexes in solution, for perfect matching and mismatching probes ...
arxiv +1 more source
BMC Genomics, 2008 Background Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations.
Hulme Helen +5 more
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DNA sequence correlations shape nonspecific transcription factor-DNA binding affinity [PDF]
Biophys. J. 101(1), 160-166 (2011), 2011 Transcription factors (TFs) are regulatory proteins that bind DNA in promoter regions of the genome and either promote or repress gene expression. Here we predict analytically that enhanced homo-oligonucleotide sequence correlations, such as poly(dA:dT) and poly(dC:dG) tracts, statistically enhance non-specific TF-DNA binding affinity.
arxiv +1 more source
, 2010 Superparamagnetic iron oxide nanometre scale particles have been utilised as contrast agents to image staked target binding oligonucleotide arrays using MRI to correlate the signal intensity and relaxation times in different NMR ...
Bencsik, Martin +6 more
core +1 more source
High-Throughput Methods for Detection of Genetic Variation
BioTechniques, 2001 Understanding human genetic variation is currently believed to reveal the cause of individual susceptibility to disease and the large variation observed in response to treatment.
Vessela Nedelcheva Kristensen +3 more
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