Results 41 to 50 of about 131,505 (250)

NOTCH2 is neither rearranged nor mutated in t(1;19) positive oligodendrogliomas. [PDF]

PLoS ONE, 2009
The combined deletion of 1p and 19q chromosomal arms is frequent in oligodendrogliomas (OD) and has recently been shown to be mediated by an unbalanced t(1;19) translocation.
Magdalena Benetkiewicz, Ahmed Idbaih, Pierre-Yves Cousin, Blandine Boisselier, Yannick Marie, Emmanuelle Crinière, Khê Hoang-Xuan, Jean-Yves Delattre, Marc Sanson, Olivier Delattre   +9 more
doaj   +1 more source

Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays [PDF]

, 2010
Background Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much debate on the best ways to process data, to design experiments and analyse ...
AR Dabney, AR Dabney, Benjamin Chain, BM Bolstad, BP Durbin, BS Everitt, CR Hampton, D Wang, E Birney, Helen Bowen, J Fan, J Rasaiyaah, J Rasaiyaah, Jane Rasaiyaah, Jhen Tsang, John Hammond, JP Hammond, L Shi, M Noursadeghi, M Sultan, Mahdad Noursadeghi, MN McCall, PA 't Hoen, TA Patterson, TC Kroll, WE Johnson, Wilfried Posch   +26 more
core   +2 more sources

MicroRNA Expression Profiling by Bead Array Technology in Human Tumor Cell Lines Treated with Interferon-Alpha-2a

Biological Procedures Online, 2009
MicroRNAs are positive and negative regulators of eukaryotic gene expression that modulate transcript abundance by specific binding to sequence motifs located prevalently in the 3' untranslated regions of target messenger RNAs (mRNA). Interferon-alpha-2a
Siegrist Fredy, Singer Thomas, Certa Ulrich   +2 more
doaj   +3 more sources

Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays

BMC Genomics, 2008
Background Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations.
Hulme Helen, Kemp Stephen J, Noyes Harry A, Rennie Catriona, Brass Andy, Hoyle David C   +5 more
doaj   +1 more source

Normalized Affymetrix expression data are biased by G-quadruplex formation [PDF]

, 2011
Probes with runs of four or more guanines (G-stacks) in their sequences can exhibit a level of hybridization that is unrelated to the expression levels of the mRNA that they are intended to measure.
Altman, Andrew P. Harrison, Barrett, Bolstad, Burge, Cambon, Do, Dudoit, Eisen, Farhat N. Memon, Geller, Gellert, Giorgi, Graham J. G. Upton, Hammond, Harris, Hochreiter, Hubbell, Hugh P. Shanahan, Irizarry, Irizarry, Iwamoto, Kittleson, Langdon, Li, Memon, Memon, Naef, Patterson, Ringnér, Ryan, Sen, Stalteri, Upton, Upton, Walton, Wu   +36 more
core   +3 more sources

A cellulose-based bioassay for the colorimetric detection of pathogen DNA [PDF]

, 2014
Cellulose-paper-based colorimetric bioassays may be used at the point of sampling without sophisticated equipment. This study reports the development of a colorimetric bioassay based on cellulose that can detect pathogen DNA.
Goyal, Madhu, Kukol, A., Rossiter, Sharon, Saikrishnan, Deepika   +3 more
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

High-Throughput Methods for Detection of Genetic Variation

BioTechniques, 2001
Understanding human genetic variation is currently believed to reveal the cause of individual susceptibility to disease and the large variation observed in response to treatment.
Vessela Nedelcheva Kristensen, Dimitris Kelefiotis, Tom Kristensen, Anne-Lise Børresen-Dale   +3 more
doaj   +1 more source

Two‐Dimensional Materials as a Multiproperty Sensing Platform

Advanced Functional Materials, EarlyView.
Various sensing modalities enabled and/or enhanced by two‐dimensional (2D) materials are reviewed. The domains considered for sensing include: 1) optoelectronics, 2) quantum defects, 3) scanning probe microscopy, 4) nanomechanics, and 5) bio‐ and chemosensing.
Dipankar Jana, Shubhrasish Mukherjee, Dmitrii Litvinov, Magdalena Grzeszczyk, Sergey Grebenchuk, Makars Šiškins, Virgil Gavriliuc, Yihang Ouyang, Changyi Chen, Yuxuan Ye, Meng Yiming, Maciej Koperski   +11 more
wiley   +1 more source

High-throughput Microarray Detection of Vomeronasal Receptor Gene Expression in Rodents

Frontiers in Neuroscience, 2010
We performed comprehensive data mining to explore the vomeronasal receptor (V1R & V2R) repertoires in mouse and rat using the mm5 and rn3 genome, respectively.
Xiaohong Zhang, Florencia Marcucci, Stuart Firestein   +2 more
doaj   +1 more source