Comparison of Analytical and Clinical Performance of HPV 9G DNA Chip, PANArray HPV Genotyping Chip, and Hybrid-Capture II Assay in Cervicovaginal Swabs [PDF]
Background: Human papillomavirus (HPV) infection can be detected by using several molecular methods, including Hybrid-Capture II (HC2) assay and variable HPV DNA chip tests, although each method has different sensitivities and specificities.
Ho Young Jung +5 more
doaj +1 more source
A Brassica exon array for whole-transcript gene expression profiling [PDF]
Affymetrix GeneChip® arrays are used widely to study transcriptional changes in response to developmental and environmental stimuli. GeneChip® arrays comprise multiple 25-mer oligonucleotide probes per gene and retain certain advantages over direct ...
King Graham J. +54 more
core +1 more source
Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]
Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Leberre, Véronique +5 more
core +1 more source
Optimising the analysis of transcript data using high density oligonucleotide arrays and genomic DNA-based probe selection [PDF]
Background: Affymetrix GeneChip arrays are widely used for transcriptomic studies in a diverse range of species. Each gene is represented on a GeneChip array by a probe-set, consisting of up to 16 probe-pairs. Signal intensities across probe-pairs within
Sean T May +14 more
core +1 more source
Using genomic DNA-based probe-selection to improve the sensitivity of high-density oligonucleotide arrays when applied to heterologous species [PDF]
High-density oligonucleotide (oligo) arrays are a powerful tool for transcript profiling. Arrays based on GeneChip® technology are amongst the most widely used, although GeneChip® arrays are currently available for only a small number of plant and animal
Craigon, David J. +23 more
core +1 more source
Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays [PDF]
Background: Alternative mRNA processing mechanisms lead to multiple transcripts (i.e. splice isoforms) of a given gene which may have distinct biological functions.
Clemens D Cohen +27 more
core +1 more source
Comparison of three microarray probe annotation pipelines: differences in strategies and their effect on downstream analysis [PDF]
BACKGROUND: Reliable annotation linking oligonucleotide probes to target genes is essential for functional biological analysis of microarray experiments.
Groenen, M.A. +18 more
core +1 more source
A Revised Design for Microarray Experiments to Account for Experimental Noise and Uncertainty of Probe Response [PDF]
Background Although microarrays are analysis tools in biomedical research, they are known to yield noisy output that usually requires experimental confirmation.
Noble, P. +23 more
core +2 more sources
New methods to analyse microarray data that partially lack a reference signal. [PDF]
BACKGROUND: Microarray-based Comparative Genomic Hybridisation (CGH) has been used to assess genetic variability between bacterial strains. Crucial for interpretation of microarray data is the availability of a reference to compare signal intensities to ...
Lindsay Jodi A +14 more
core +1 more source
Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the proteins [PDF]
The combination of complete genome sequence information with expression data enables us to characterize the relationship between a protein's evolutionary origin or functional category and its expression pattern.
Thornton, Janet M +6 more
core +1 more source

