Results 21 to 30 of about 23,719,178 (251)

Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays [PDF]

, 2009
Background: Alternative mRNA processing mechanisms lead to multiple transcripts (i.e. splice isoforms) of a given gene which may have distinct biological functions.
Clemens D Cohen, Nelson Peter J., Moll, Anton G., Moll Anton G., Ralf Zimmer, Maja T. Lindenmeyer, Lindenmeyer, M T, Cohen Clemens D., Nelson, Peter J., Nelson, P J, Kretzler, Matthias, Zimmer, Ralf, Zimmer Ralf, Anton G Moll, Maja T Lindenmeyer, Cohen, Clemens D., Kretzler, M, Anton G. Moll, Matthias Kretzler, Lindenmeyer, Maja T., Cohen, C D, Peter J. Nelson, Moll, A G, Peter J Nelson, Zimmer, R, Kretzler Matthias, Lindenmeyer Maja T., Clemens D   +27 more
core   +2 more sources

Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays [PDF]

, 2010
Background Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much debate on the best ways to process data, to design experiments and analyse ...
Tsang, Jhen, Hammond, J., Bowen, H., Jane Rasaiyaah, Noursadeghi, M., Posch, W., Helen Bowen, Wilfried Posch, Hammond, John, Chain, B., Chain, B. M., Chain, Benjamin, Benjamin Chain, Noursadeghi, Mahdad, Mahdad Noursadeghi, John Hammond, Bowen, Helen C., Rasaiyaah, Jane, Hammond, John P., Rasaiyaah, J., Posch, Wilfried, Tsang, J., Jhen Tsang, Bowen, Helen   +23 more
core   +1 more source

Microarray generation of thousand-member oligonucleotide libraries. [PDF]

PLoS ONE, 2011
The ability to efficiently and economically generate libraries of defined pieces of DNA would have a myriad of applications, not least in the area of defined or directed sequencing and synthetic biology, but also in applications associated with encoding ...
Nina Svensen, Juan José Díaz-Mochón, Mark Bradley   +2 more
doaj   +1 more source

Comparison of three microarray probe annotation pipelines: differences in strategies and their effect on downstream analysis [PDF]

, 2009
BACKGROUND: Reliable annotation linking oligonucleotide probes to target genes is essential for functional biological analysis of microarray experiments.
Groenen, M.A., Leunissen, J.A., Neerincx, P.B.T., Groenen, M.A.M., Pierrot Casel, Casel, P., Michael Watson, Neerincx, P.B., Christophe Klopp, Klopp, C., Pieter Neerincx, Dennis Prickett, Martien Groenen, Nie, H., Jack Leunissen, Haisheng Nie, Watson, M., Leunissen, J.A.M., Prickett, D.   +18 more
core   +1 more source

Experimental optimization of probe length to increase the sequence specificity of high-density oligonucleotide microarrays

BMC Genomics, 2007
Background High-density oligonucleotide arrays are widely used for analysis of genome-wide expression and genetic variation. Affymetrix GeneChips – common high-density oligonucleotide arrays – contain perfect match (PM) and mismatch (MM) probes generated
Kashiwagi Akiko, Furusawa Chikara, Ono Naoaki, Suzuki Shingo, Yomo Tetsuya   +4 more
doaj   +1 more source

Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis [PDF]

, 2008
Background: Diabetic nephropathy (DN) is a complex and chronic metabolic disease that evolves into a progressive fibrosing renal disorder. Effective transcriptomic profiling of slowly evolving disease processes such as DN can be problematic.
Seifert, Martin, Hermann-Josef Gröne, Gröne, H J, Nelson, P. J., Felix Eichinger, Moll, Anton G., Kiss, Eva, Lindenmeyer, M T, Grone, E., Kiss, E, Nelson, P J, Gröne, Elisabeth, Anton G Moll, Schmid, H., Grone, H. J., Matthias Kretzler, Lindenmeyer, Maja T., Cohen, C D, Alexander Hahn, Moll, A G, Gröne, E, Holger Schmid, Hahn, A, Eichinger, F, Werner, T, Eichinger, F., Hahn, Alexander, Clemens D Cohen, Schmid, H, Martin Seifert, Kretzler, M., Werner, Thomas, Hahn, A., Seifert, M., Lindenmeyer, M. T., Kiss, E., Eichinger, Felix, Nelson, Peter J., Seifert, M, Kretzler, Matthias, Maja T Lindenmeyer, Cohen, Clemens D., Kretzler, M, Elisabeth Gröne, Gröne, Hermann-Josef, Peter J Nelson, Schmid, Holger, Eva Kiss, Cohen, C. D., Werner, T., Thomas Werner   +50 more
core   +1 more source

A Revised Design for Microarray Experiments to Account for Experimental Noise and Uncertainty of Probe Response [PDF]

, 2014
Background Although microarrays are analysis tools in biomedical research, they are known to yield noisy output that usually requires experimental confirmation.
Noble, P., Alex E. Pozhitkov (62910), Bryk, Jarek, Pozhitkov, A., Kaderali, Lars, Pozhitkov Alex E., Tautz Diethard, Tautz, D. ; https://orcid.org/, Alex E. Pozhitkov, Bryk, Jaroslaw, Diethard Tautz, Jarosław Bryk, Pozhitkov, Alex E., Peter A Noble, Diethard Tautz (17015), Noble Peter A., Jarosław Bryk (47108), Peter A. Noble, Bryk Jarosław, Bryk, J., Alex E Pozhitkov, Peter A. Noble (17009), Noble, Peter A., Tautz, Diethard   +23 more
core   +1 more source

Microarrays and infectious diseases: overview and perspectives [PDF]

Einstein (São Paulo), 2005
Disease investigation is evolving in the light of the human genomeavailability and the complete genome sequencing of several humanpathogens. Microarray technology is a revolutionary tool for elucidatingroles of genes in infectious diseases, shifting from
Patricia Severino
doaj  

Combining gene expression data from different generations of oligonucleotide arrays

BMC Bioinformatics, 2004
Background One of the important challenges in microarray analysis is to take full advantage of previously accumulated data, both from one's own laboratory and from public repositories.
Kong Sek, Hwang Kyu-Baek, Greenberg Steve A, Park Peter J   +3 more
doaj   +1 more source

Design, validation and annotation of transcriptome-wide oligonucleotide probes for the oligochaete annelid Eisenia fetida. [PDF]

PLoS ONE, 2010
High density oligonucleotide probe arrays have increasingly become an important tool in genomics studies. In organisms with incomplete genome sequence, one strategy for oligo probe design is to reduce the number of unique probes that target every non ...
Ping Gong, Mehdi Pirooznia, Xin Guan, Edward J Perkins   +3 more
doaj   +1 more source