Results 31 to 40 of about 80,761 (229)

A strategy for detection of known and unknown SNP using a minimum number of oligonucleotides applicable in the clinical settings

Journal of Translational Medicine, 2003
Detection of unknown single nucleotide polymorphism (SNP) relies on large scale sequencing expeditions of genomic fragments or complex high-throughput chip technology.
Klein Harvey, Simon Richard, Panelli Monica, Zhao Yingdong, Adams Sharon, Wang Ena, Marincola Francesco M   +6 more
doaj   +1 more source

Multilocus sequence typing of Staphylococcus aureus with DNA array technology [PDF]

, 2003
A newly developed oligonucleotide array suited for multilocus sequence typing (MLST) of Staphylococcus aureus strains was analyzed with two strain collections in a two-center study.
Jay, C. (Corinne), Snijders, S.V. (Susan), Troesch, A, Leeuwen, Willem, Enright, MC, Troesch, A. (Alain), Verbrugh, H.A. (Henri), Belkum, Alex, Lacroix, B, Belkum, A.F. (Alex) van, Snijders, Susan, Enright, M.C. (Mark), Leeuwen, W.B. (Willem) van, Lacroix, B. (Bruno), Jay, C, Durin, N. (Nathalia), Verbrugh, Henri, Durin, N   +17 more
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Identical probes on different high-density oligonucleotide microarrays can produce different measurements of gene expression

BMC Genomics, 2006
Background There are many potential sources of variability in a microarray experiment. Variation can arise from many aspects of the collection and processing of samples for gene expression analysis.
Enkemann Steven A, Yoder Sean J, Zhang LanMin   +2 more
doaj   +1 more source

Functional genomic analysis of developmental control gene action in the embryonic nervous system of "Drosophila" [PDF]

, 2003
In the past two decades, developmental genetic analysis of the molecular control elements involved in early embryonic brain patterning has uncovered the existence of structurally and functionally homologous genes that have comparable, and indeed ...
Montalta-He, Haiqiong
core   +1 more source

DNA microarrays in cancer diagnosis and prognosis [PDF]

Einstein (São Paulo), 2005
This review discusses recent advances in our understanding ofthe human genome and the application of derived technologies inthe medical area. It focuses on the use of DNA microarray fordiagnosis, prognosis, and therapeutic purposes in oncology, andthe ...
Oswaldo Keith Okamoto
doaj  

Design and evaluation of Actichip, a thematic microarray for the study of the actin cytoskeleton

BMC Genomics, 2007
Background The actin cytoskeleton plays a crucial role in supporting and regulating numerous cellular processes. Mutations or alterations in the expression levels affecting the actin cytoskeleton system or related regulatory mechanisms are often ...
Chalmel Frédéric, Muller Arnaud, Yatskou Mikalai, Vetter Guillaume, Mehlen André, Muller Jean, Poch Olivier, Friederich Evelyne, Vallar Laurent   +8 more
doaj   +1 more source

Whole genome comparative studies between chicken and turkey and their implications for avian genome evolution [PDF]

, 2008
BACKGROUND: Comparative genomics is a powerful means of establishing inter-specific relationships between gene function/location and allows insight into genomic rearrangements, conservation and evolutionary phylogeny.
Griffin, D.K., Gaginskaya, E., Robertson, L. B., Völker Martin, Masabanda, Julio S., Burt, D.W., Valérie Fillon, Svetlana Deryusheva, Robertson Lindsay B, Griffin Darren K, Fillon, V., Masabanda, J. S., Martin Völker, Richard Talbot, Crooijmans, Richard P.M.A., Darren K Griffin, Gaginskaya, Elena, Vignal Alain, Martien AM Groenen, Crooijmans, Richard P. M. A., Dave W Burt, Groenen, M.A.M., Burt Dave W, Robertson, L.B., Griffin, D. K., Burt, D. W., Helen G Tempest, Carre, Wilfrid, Vignal, Alain, Julio S Masabanda, Crooijmans, R.P.M.A., Burt, Dave W, Tempest, H.G., Groenen, Martien A. M., Griffin, Darren K., Deryusheva, Svetlana, Waddington David, Talbot, Richard, Waddington, D., Robertson, Lindsay B., Robertson, Lindsay, Carré Wilfrid, Masabanda, Julio S, Groenen, Martien AM, Tempest, Helen G., Gaginskaya Elena, Fillon Valérie, Burt, Dave W., Waddington, David, Tempest, H. G., Groenen Martien AM, Fillon, Valerie, Lindsay B Robertson, Talbot Richard, Crooijmans, R. P., Deryusheva, S., Elena Gaginskaya, Masabanda Julio S, Tempest Helen G, Volker, Martin, Crooijmans, Richard PMA, Groenen, M. A., David Waddington, Deryusheva Svetlana, Talbot, R., Wilfrid Carré, Richard PMA Crooijmans, Masabanda, J.S., Vignal, A., Alain Vignal, Burt, David W., Crooijmans Richard PMA, Volker, M., Carre, W.   +73 more
core   +1 more source

A comparison of alternative 60-mer probe designs in an in-situ synthesized oligonucleotide microarray

BMC Genomics, 2006
Background DNA microarrays have proven powerful for functional genomics studies. Several technologies exist for the generation of whole-genome arrays.
Fairbanks Benjamin D, Hume Patrick S, Karimpour-Fard Anis, Leiske Danielle L, Gill Ryan T   +4 more
doaj   +1 more source

NOTCH2 is neither rearranged nor mutated in t(1;19) positive oligodendrogliomas. [PDF]

PLoS ONE, 2009
The combined deletion of 1p and 19q chromosomal arms is frequent in oligodendrogliomas (OD) and has recently been shown to be mediated by an unbalanced t(1;19) translocation.
Magdalena Benetkiewicz, Ahmed Idbaih, Pierre-Yves Cousin, Blandine Boisselier, Yannick Marie, Emmanuelle Crinière, Khê Hoang-Xuan, Jean-Yves Delattre, Marc Sanson, Olivier Delattre   +9 more
doaj   +1 more source

Functional genomics of brain development and developmentally related brain disease in "Drosophila" [PDF]

, 2004
One of the fundamental challenges in basic neuroscience is to understand the molecular genetic networks associated with building the brain. As malfunction in these genetic pathways can lead to disorders like cancer, brain development is also a crucial ...
Loop, Thomas
core   +1 more source