Results 81 to 90 of about 149,559 (187)

Discovery and mapping of single feature polymorphisms in wheat using Affymetrix arrays

BMC Genomics, 2009
Background Wheat (Triticum aestivum L.) is a staple food crop worldwide. The wheat genome has not yet been sequenced due to its huge genome size (~17,000 Mb) and high levels of repetitive sequences; the whole genome sequence may not be expected in the ...
Hu Shengwa, Ma Hongxiang, Bradbury Peter J, Bernardo Amy N, Bowden Robert L, Buckler Edward S, Bai Guihua   +6 more
doaj   +1 more source

Microarray-based analysis of differential gene expression between infective and noninfective larvae of Strongyloides stercoralis.

PLoS Neglected Tropical Diseases, 2011
BackgroundDifferences between noninfective first-stage (L1) and infective third-stage (L3i) larvae of parasitic nematode Strongyloides stercoralis at the molecular level are relatively uncharacterized. DNA microarrays were developed and utilized for this
Roshan Ramanathan, Sudhir Varma, José M C Ribeiro, Timothy G Myers, Thomas J Nolan, David Abraham, James B Lok, Thomas B Nutman   +7 more
doaj   +1 more source

Gene expression analysis identifies hypothetical genes that may be critical during the infection process of Xanthomonas citri subsp. citri

Electronic Journal of Biotechnology, 2019
Background: Gene expression analysis via microarray is widely used in phytobacteria to validate differential gene expression associated with virulence or to compare biological profiles of wild type and mutant strains. Here, we employed DNA microarrays to
Marcelo Luiz de Laia, Leandro Marcio Moreira, Janaína Fernandes Gonçalves, Maria Inês Tiraboschi Ferro, Any Caroliny Pinto Rodrigues, Jéssica Naiara dos Santos, Érica Barbosa Felestrino, Jesus Aparecido Ferro   +7 more
doaj   +1 more source

Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias

BMC Genomics, 2012
Background High-density genotyping arrays that measure hybridization of genomic DNA fragments to allele-specific oligonucleotide probes are widely used to genotype single nucleotide polymorphisms (SNPs) in genetic studies, including human genome-wide ...
Didion John P, Yang Hyuna, Sheppard Keith, Fu Chen-Ping, McMillan Leonard, de Villena Fernando, Churchill Gary A   +6 more
doaj   +1 more source

Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation

BMC Bioinformatics, 2008
Background Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good prognosis, and identify patients likely to have disease recurrence. However,
Lundberg Cathryn, Snøve Ola, Sætrom Pål, Smith David D, Rivas Guillermo E, Glackin Carlotta, Larson Garrett P   +6 more
doaj   +1 more source

MicroRNA detection on microsensor arrays by SPR imaging measurements with enzymatic signal enhancement. [PDF]

, 2019
We investigated sequence-specific and simultaneous microRNA (miRNA) detections by surface plasmon resonance (SPR) imaging measurements on SPR chips possessing an Au spot array modified with probe DNAs based on a miRNA-detection-selective SPR signal ...
Aoki, Hiroshi, Corn, Robert M, Matthews, Brandon   +2 more
core  

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

Molecular Cancer, 2006
Background Somatic mutations of mitochondrial DNA (mtDNA) are common in many human cancers. We have described an oligonucleotide microarray ("MitoChip") for rapid sequencing of the entire mitochondrial genome (Zhou et al, J Mol Diagn 2006), facilitating ...
Montgomery Elizabeth A, Eshleman James R, Lee Edward E, Canto Marcia, Wang Jean, Zhou Shaoyu, Sui Guoping, Sidransky David, Califano Joseph A, Maitra Anirban   +9 more
doaj   +1 more source

Software and methods for oligonucleotide and cDNA array data analysis. [PDF]

, 2002
Two HTML-based programs were developed to analyze and filter gene-expression data: 'Bullfrog' for Affymetrix oligonucleotide arrays and 'Spot' for custom cDNA arrays. The programs provide intuitive data-filtering tools through an easy-to-use interface. A
Barlow, Carrolee, Garcia, Anthony J, Lockhart, Daniel J, Lockhart, David J, Pankratz, Daniel G, Zapala, Matthew A   +5 more
core   +1 more source

MIMAS 3.0 is a Multiomics Information Management and Annotation System

BMC Bioinformatics, 2009
Background DNA sequence integrity, mRNA concentrations and protein-DNA interactions have been subject to genome-wide analyses based on microarrays with ever increasing efficiency and reliability over the past fifteen years.
Rougemont Jacques, Collin Olivier, Xenarios Ioannis, Liechti Robin, Hermida Leandro, Gattiker Alexandre, Primig Michael   +6 more
doaj   +1 more source

Genome-wide mapping of ORC and Mcm2p binding sites on tiling arrays and identification of essential ARS consensus sequences in S. cerevisiae

BMC Genomics, 2006
Background Eukaryotic replication origins exhibit different initiation efficiencies and activation times within S-phase. Although local chromatin structure and function influences origin activity, the exact mechanisms remain poorly understood.
Aparicio Oscar M, Aparicio Jennifer G, Xu Weihong, Tavaré Simon   +3 more
doaj   +1 more source