Results 211 to 220 of about 152,205 (267)
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An oligonucleotide probe specific for Onchocerca volvulus
Molecular and Biochemical Parasitology, 1989A genomic DNA library of a Liberian strain of Onchocerca volvulus was prepared in the vector bacteriophage lambda gt10. The library was differentially screened by hybridisation with radiolabelled total DNA from the homologous parasite, two heterologous Onchocerca parasites (Onchocerca gibsoni and Onchocerca gutturosa) and human liver cells.
W, Harnett +3 more
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Oligonucleotide probe design — a new approach
Nature, 1994The use of oligonucleotides for gene amplification, as diagnostic probes or antisense-based drugs can be optimized by minimizing the possibility of nonspecific hybridization.
M, Mitsuhashi +5 more
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Oligonucleotide probes for DNA fingerprinting in horses
Journal of Animal Breeding and Genetics, 1993Summary10 different oligonucleotide probes were evaluated for DNA fingerprinting in horses. Five probes were able to detect polymorphic bands. The probes (GT)8, (GTG)5 and (GGAT)4 are most informative for individual identification and were used to analyze a population of Hannoveranian horses.
K, Wilke +3 more
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Probe Design Strategies for Oligonucleotide Microarrays
2016Oligonucleotide microarrays have been widely used for gene detection and/or quantification of gene expression in various samples ranging from a single organism to a complex microbial assemblage. The success of a microarray experiment, however, strongly relies on the quality of designed probes.
Parisot, Nicolas +5 more
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Oligonucleotide probes for DNA fingerprinting in dogs
Journal of Animal Breeding and Genetics, 1994SummaryTen different oligonucleotide probes were evaluated for DNA fingerprinting in dogs. Seven probes are able to detect polymorphic bands. Probes (GT)8, (GTG)5 and (GGAT)4 are most informative for individual identification. The probabilities that two individuals from different breeds have the same DNA fingerprint pattern are 1.7 × 10−7, 5.5 × 10−8 ...
M, Jung, K, Wilke, H, Geldermann
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Optimized oligonucleotide probes for DNA fingerprinting
ELECTROPHORESIS, 1988AbstractThe three different simple repetitive oligonucleotide probes (CT)8, (CAC)5 and (TCC)5 were hybridized to a panel of human DNAs which had been digested with the restriction endonucleases Alu I, Hinf I and Mbo I. The resulting DNA fingerprints were analyzed and different parameters calculated, such as the maximal mean allele frequency and the ...
R, Schäfer +4 more
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Oligonucleotide probes functionalization of nanogap electrodes
ELECTROPHORESIS, 2017AbstractNanogap electrodes have attracted a lot of consideration as promising platform for molecular electronic and biomolecules detection. This is mainly for their higher aspect ratio, and because their electrical properties are easily accessed by current‐voltage measurements. Nevertheless, application of standard current‐voltages measurements used to
Rosa Letizia Zaffino +2 more
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Microarray oligonucleotide probes.
Methods in enzymology, 2006Oligonucleotide probes are increasingly the method of choice for many modern DNA microarray applications. They provide higher target specificity, probe selection gives improved experimental control of hybridization properties, and targeting of specific gene subsequences allows better discrimination of highly similar targets such as splice variants or ...
David P, Kreil +2 more
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Oligonucleotides as targets and cellular probes
Bioorganic & Medicinal Chemistry, 2013openaire +2 more sources