Results 31 to 40 of about 222,321 (300)

Development of a microfluidic biosensor for the diagnostics and typing of Mycobacterium Tuberculosis [PDF]

Клиническая практика, 2021
Background. Despite on the general trend towards decreasing the incidence of newly diagnosed active forms of tuberculosis, the situation with spreading of this disease in Russian Federation remains extremely tense.
Tatiana V. Mitko, Ruslan I. Shakurov, Fedor V. Shirshikov, Sizova V. Svetlana, Elena V. Alieva, Valery N. Konopsky, Dmitry V. Basmanov, Julia A. Bespyatykh   +7 more
doaj   +1 more source

Multiparametric determination of genes and their point mutations for identification of beta-lactamases [PDF]

, 2010
More than half of all currently used antibiotics belong to the beta-lactam group, but their clinical effectiveness is severely limited by antibiotic resistance of microorganisms that are the causative agents of infectious diseases. Several mechanisms for
A. A. Medeiros, A. Bauernfield, A. J. Brookes, A. M. Egorov, A. Nikulin, A. Philippon, A. Tamilselvi, A. Yu. Rubina, B. E. E. Cleven, B. Strommenger, C. C. Randegger, C. D. Steward, C. Heritier, C. Heritier, C. I. Birkett, C. Mabilat, C. Mugnaioli, D. E. Mudrak, D. Gryadunov, D. L. Paterson, D. L. Paterson, D. L. Paterson, D. M. Leinberger, D. M. Livermore, D. M. Livermore, D. M. Livermore, D. M. Livermore, D. M. Livermore, D. Szabo, D. V. Ivanov, E. B. Chaibi, E. M. Southern, F. Hayes, F. J. L. Robberts, F. Perez, F.-H. M’Zali, G. F. Weldhagen, H. C. Maltezou, H. F. Chambers, H. J. Monstein, H. Knothe, H. Wang, I. Massova, I. Rodriguez, I. Weigand, I. Wiegand, J. D. D. Pitout, J. D. D. Pitout, J. D. Pitout, J. D. Pitout, J. Empel, J. F. Petrosino, J. L. Jones, J. M. Ghuysen, J. Rodriguez-Bano, J. Schlesinger, J. Schmitt, J. W. Schumm, K. Bush, K. Bush, K. Bush, L. Bodrossy, L. Drieux, L. N. Ikryannikova, L. Pagani, L. Poirel, L. Poirel, L. S. Tzouvelekis, L. X. Zhu, L. Xu, L. Xu, M. Babic, M. Batchelor, M. Cassone, M. Chee, M. Edelstein, M. F. Lartigue, M. Guckenberger, M. H. Richmond, M. I. Page, M. J. Heller, M. J. Schwaber, M. J. Schwaber, M. M. Ulyashova, M. M. Ulyashova, M. Nukaga, M. Ozsoz, M. Quinteros, M. R. Mulvey, M. Schena, M. Shogo, M. Yu. Rubtsova, N. C. Strynadka, N. Datta, N. Shibata, N. Woodford, N. Woodford, P. A. James, P. Bradford, P. C. Fleming, P. M. Hawkey, R. Alonso, R. B. Sykes, R. Bonnet, R. Bonnet, R. Canton, R. D. Schmid, R. P. Ambler, S. Chen, S. Egorova, S. Harada, S. K. Du Bois, S. Kalai Blagui, S. V. Sidorenko, S. V. Sidorenko, T. L. Wu, T. Naas, T. R. Hughes, T. T. Bachmann, V. A. Doss, V. Chizhikov, V. Grimm, V. M. Ensor, V. Perreten, X. Cao, X. Yu, Y. Lee, Y. Michikawa   +127 more
core   +1 more source

Use of a Multiplexed CMOS Microarray to Optimize and Compare Oligonucleotide Binding to DNA Probes Synthesized or Immobilized on Individual Electrodes

Sensors, 2010
The CombiMatrix microarray with 12,544 electrodes supports in situ electrochemical synthesis of user-defined DNA probes. As an alternative, we immobilized commercially synthesized DNA probes on individual electrodes coated with electropolymerized ...
David Danley, Wanda Lyon, John Cooper, Jodi Wilmoth, Nina Yazvenko, Karl Maurer   +5 more
doaj   +1 more source

Locked nucleic acid: tighter is different [PDF]

, 2013
This viewpoint briefly reviews the impact of Locked Nucleic Acid (LNA) oligonucleotides, first described in a ChemComm paper in 1998. A number of unique applications in oligonucleotide biotechnology have been made possible by the high binding affinity ...
Watts, Jonathan
core   +1 more source

FastTag™ Nucleic Acid Labeling System: A Versatile Method for Incorporating Haptens, Fluorochromes and Affinity Ligands into DNA, RNA and Oligonucleotides

BioTechniques, 1998
The FastTag™ Nucleic Acid Labeling System couples haptens, fluorochromes or affinity ligands to any nucleic acid by attaching a universal, photo- or heat-activatable moiety to which any sulfhydryl-reactive compound can be linked.
Steven G. Daniel, Mark E. Westling, Michele S. Moss, Brian D. Kanagy   +3 more
doaj   +1 more source

Development, characterization and experimental validation of a cultivated sunflower (Helianthus annuus L.) gene expression oligonucleotide microarray. [PDF]

PLoS ONE, 2012
Oligonucleotide-based microarrays with accurate gene coverage represent a key strategy for transcriptional studies in orphan species such as sunflower, H. annuus L., which lacks full genome sequences.
Paula Fernandez, Marcelo Soria, David Blesa, Julio DiRienzo, Sebastian Moschen, Maximo Rivarola, Bernardo Jose Clavijo, Sergio Gonzalez, Lucila Peluffo, Dario Príncipi, Guillermo Dosio, Luis Aguirrezabal, Francisco García-García, Ana Conesa, Esteban Hopp, Joaquín Dopazo, Ruth Amelia Heinz, Norma Paniego   +17 more
doaj   +1 more source

Design and evaluation of 16S rRNA sequence based oligonucleotide probes for the detection and quantification of Comamonas testosteroni in mixed microbial communities [PDF]

, 2006
Background The β-proteobacterial species Comamonas testosteroni is capable of biotransformation and also biodegradation of a range of chemical compounds and thus potentially useful in chemical manufacturing and bioremediation.
Bathe, Stephan, Hausner, Martina
core   +1 more source

ProbeMaker: an extensible framework for design of sets of oligonucleotide probes

BMC Bioinformatics, 2005
Background Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material.
Nilsson Mats, Stenberg Johan, Landegren Ulf   +2 more
doaj   +1 more source

Microarray-based ultra-high resolution discovery of genomic deletion mutations [PDF]

, 2014
BACKGROUND: Oligonucleotide microarray-based comparative genomic hybridization (CGH) offers an attractive possible route for the rapid and cost-effective genome-wide discovery of deletion mutations.
Baban, D., Belfield, E., Brown, C., Gan, X., Harberd, N., Jiang, C., Mithani, A., Mott, R., Ragoussis, J.   +8 more
core   +3 more sources

Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays

BMC Bioinformatics, 2010
Background Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcriptome of microbial genomes using a tiling probe design.
Chen Tsute, Høvik Hedda
doaj   +1 more source