Results 241 to 250 of about 449,240 (358)

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

open access: yesAdvanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang   +8 more
wiley   +1 more source

Mapping U2 snRNP--pre-mRNA interactions using biotinylated oligonucleotides made of 2′-OMe RNA. [PDF]

open access: bronze, 1989
Silvia M.L. Barabino   +4 more
openalex   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

open access: yesAdvanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan   +16 more
wiley   +1 more source

Primer‐Disk‐Enabled DNA Data Storage System with Index and Record‐Many‐Read‐Many Features

open access: yesAdvanced Science, EarlyView.
A primer‐disk‐enabled DNA data storage system is introduced, which allows for append‐recording of DNA files on demand, retrieval via inkjet printed QR code, and multiple ramdom read of DNA information via solid‐phase PCR. The hiearchical system with index and record‐many‐read‐many features paves the way for the practical use of DNA data storage ...
Jiaxiang Ma   +5 more
wiley   +1 more source

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