Results 251 to 260 of about 584,539 (379)

Antisense oligonucleotides in therapy for neurodegenerative disorders.

Advanced Drug Delivery Reviews, 2015
M. Evers, L. Toonen, W. V. van Roon-Mom
semanticscholar   +1 more source

cDC1 Subtype‐Specific In Vivo Targeting of Liposomes

Advanced Science, EarlyView.
Dendritic cells, particularly the cDC1 subtype, offer a promising target for drug delivery via liposomes due to their pivotal role in immune regulation, allowing for amplified therapeutic responses. Herein, we show an integration of physicochemical characterization and cell experiments to achieve effective in vivo cDC1 targeting through anti‐CLEC9A ...
Maximilian Schaaf, Michael Fichter, Lin Jian, Felicia Schön, Carina Jung, Paul Schneider, Kai Speth, Ana Mateos‐Maroto, Volker Mailänder, Kaloian Koynov, Svenja Morsbach, Katharina Landfester   +11 more
wiley   +1 more source

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

, 1998
Sandy D. Der, Aimin Zhou, Bryan Williams, Robert H. Silverman   +3 more
openalex   +2 more sources

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Editorial: Recent advancements in RNA-based and targeted therapeutics

Frontiers in Genetics
Yiming Meng, Viola Bianca Serio, Viola Bianca Serio, Yuquan Tong, Tao Huang, Elisa Frullanti, Elisa Frullanti, Maria Palmieri, Maria Palmieri   +8 more
doaj   +1 more source

Hydrophobic alkyl-linked base-modified pyrimidine and 7-deazapurine 2'-deoxyribonucleoside phosphoramidites: synthesis and application in solid-phase synthesis of modified and hypermodified oligonucleotides. [PDF]

RSC Adv
Jestřábová I, Bednárová L, Poštová Slavětínská L, Hocek M.   +3 more
europepmc   +1 more source

Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy

, 2011
Marco A. Passini, Jie Bu, Amy M. Richards, Cathrine Kinnecom, S. Pablo Sardi, Lisa M. Stanek, Yimin Hua, Frank Rigo, John Matson, Gene Hung, Edward M. Kaye, Lamya S. Shihabuddin, Adrian R. Krainer, C. Frank Bennett, Seng H. Cheng   +14 more
openalex   +2 more sources

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Coumarin-Based Photolabile Solid Support Facilitates Nonchromatographic Purification of RNA Oligonucleotides. [PDF]

J Org Chem
McClain I, Dagci H, Pandit B, Royzen M.
europepmc   +1 more source

The Effect of Chain Length on the Phosphorolysis of Oligonucleotides by Polynucleotide Phosphorylase

, 1970
Janice Y. Chou, Maxine Singer
openalex   +1 more source