Results 31 to 40 of about 584,539 (379)
Frontiers in Microbiology, 2019 Optical biosensors for rapid detection of significant foodborne pathogens are steadily gaining popularity due to its simplicity and sensitivity. While nanomaterials such as gold nanoparticles (AuNPs) are commonly used as signal amplifiers for optical ...
Irwin A. Quintela +5 more
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Cells, 2022 Target modulation of the AhR for inflammatory gastrointestinal (GI) conditions holds great promise but also the potential for safety liabilities both within and beyond the GI tract.
Samantha C. Faber +7 more
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Future Perspectives of Oral Delivery of Next Generation Therapies for Treatment of Skin Diseases
Pharmaceutics, 2021 Gene therapies have conspicuously bloomed in recent years as evidenced by the increasing number of cell-, gene-, and oligo-based approved therapies.
Pia Pernille Søgaard +5 more
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Activity modulation and allosteric control of a scaffolded DNAzyme using a dynamic DNA nanostructure. [PDF]
, 2016 Recognition of the fundamental importance of allosteric regulation in biology dates back to not long after its discovery in the 1960s. Our ability to rationally engineer this potentially useful property into normally non-allosteric catalysts, however ...
Fan, Chunhai +7 more
core +1 more source
ChemistryOpen, 2020 DNA was used as supramolecular scaffold to order chromophores and control their optical properties. Ethynylpyrene as energy donor was attached to 2′‐desoxy‐2‐aminoadenosine that binds selectively to thymidines (T) in the template.
Sara Müller +2 more
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Molecular Mechanisms of Antisense Oligonucleotides
Nucleic Acid Therapeutics, 2017 In 1987, when I became interested in the notion of antisense technology, I returned to my roots in RNA biochemistry and began work to understand how oligonucleotides behave in biological systems.
S. Crooke
semanticscholar +1 more source
Early stages of retinal development depend on Sec13 function [PDF]
, 2013 Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia +3 more
core +3 more sources
Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase. [PDF]
, 2019 Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and ...
Cui, Xianshu +6 more
core +1 more source
Molecules, 2012 There is considerable attention directed at chemically modifying nucleic acids with robust functional groups in order to alter their properties. Since the breakthrough of copper-assisted azide-alkyne cycloadditions (CuAAC), there have been several ...
Wei Gong +2 more
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Проблемы особо опасных инфекций, 2020 Objective of the study is to analyze the genetic markers of tick-borne encephalitis virus, which can be used to specifically indicate the maximum number of virus strains and isolates.Materials and methods.
N. I. Khammadov
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