Results 101 to 110 of about 458,280 (341)

Synthesis of Streptococcus pneumoniae serotype 9V oligosaccharide antigens

Beilstein Journal of Organic Chemistry, 2020
Streptococcus pneumoniae (SP) bacteria cause serious invasive diseases. SP bacteria are covered by a capsular polysaccharide (CPS) that is a virulence factor and the basis for SP polysaccharide and glycoconjugate vaccines.
Sharavathi G. Parameswarappa, Claney L. Pereira, Peter H. Seeberger   +2 more
doaj   +1 more source

Animal lectins as cell adhesion molecules [PDF]

, 1998
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core   +1 more source

T‐2 Toxin Exploits Gut‐Derived Staphylococcus Saprophyticus to Disrupt Hepatic Macrophage Homeostasis

Advanced Science, EarlyView.
T‐2 toxin promotes the proliferation of intestinal S. saprophyticus and facilitates its translocation to the liver in piglets and mice. The translocated bacteria trigger autophagy in Kupffer cells and recruit monocytes to the liver through the nucleotide‐binding oligomerization domain 2 (NOD2) signaling pathway, alongside the M1 polarization of hepatic
Yuanyuan Zhu, Liu Xu, Fangrui Guo, Jianyu Qu, Xiangyan Liu, Qiurong Xu, Jie Sheng, Jiangping Wang, Xiaohong Xie, Ruimin Ren, Chuan Zhou, Sisi Yan, Shuiping Liu, Zhihang Yuan, Rongfang Li, Jing Wu, Jine Yi, Yulong Yin, Lixin Wen, Ji Wang   +19 more
wiley   +1 more source

Characterization of the Lipopolysaccharide from a \u3cem\u3eRhizobium phaseoli\u3c/em\u3e Mutant that is Defective in Infection Thread Development [PDF]

, 1987
The lipopolysaccharide (LPS) from a Rhizobium phaseoli mutant, CE109, was isolated and compared with that of its wild-type parent, CE3. A previous report has shown that the mutant is defective in infection thread development, and sodium dodecyl sulfate ...
Carlson, Russell W., Kalembasa, Stanislaw, Noel, K. Dale, Pachori, Pappi, Turowski, Debra A.   +4 more
core   +1 more source

3D Printing of α‐Amylase‐Illuminated Fluorescent Devices for Dynamic Information Storage and Encryption

Aggregate, EarlyView.
A α‐amylase‐stimulated responsive fluorescent hydrogel system was used to store information with arbitrary architectures through combining 3D printing technology. ABSTRACT Traditional fluorescent materials for information encryption have drawbacks such as low resolution and cumbersome process of information loading.
Jiongcheng Lu, Jiawei Lin, Ran Chen, Qian Sun, Zhenxing Wang, Wen Huang, Lili Cai, Xuetao Shi, Meng Zhang, Kaojin Wang, Lin Wang, Yong‐Guang Jia, Xiaoxia Zhu   +12 more
wiley   +1 more source

High-Level Expression of a Thermally Stable Alginate Lyase Using Pichia pastoris, Characterization and Application in Producing Brown Alginate Oligosaccharide

Marine Drugs, 2018
An alginate lyase encoding gene sagl from Flavobacterium sp. H63 was codon optimized and recombinantly expressed at high level in P.pastoris through high cell-density fermentation.
Haifeng Li, Shuling Wang, Yunyi Zhang, Liehuan Chen   +3 more
doaj   +1 more source

Nanodroplet‐Array‐Plattform zur integrierten Synthese und Screening von MEK Inhibitoren: Ein miniaturisierter Ansatz für die frühe Pharmaforschung

Angewandte Chemie, EarlyView.
Wir präsentieren eine Nanodroplet‐Array‐Plattform, die die Integration von Festphasensynthese, MALDI‐MS‐Analyse und zellbasiertem Screening von 325 potenziellen MEK‐Inhibitoren (Mitogen‐aktivierte‐Proteinkinase‐Kinase) in Nanoliter‐Volumina ermöglicht.
Maximilian Seifermann, Julius Höpfner, Liana Bauer, Divya Varadharajan, Stefan Schmidt, Björn Fröhlich, Benjamin Wellenhofer, Charlotte Luchena, Carsten Hopf, Anna A. Popova, Pavel A. Levkin   +10 more
wiley   +1 more source

Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]

, 1992
The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Johnson, Judith P., Kellermann, Josef, Ulbrecht, Matthias, Weiss, Elisabeth H.   +3 more
core   +1 more source

Oligosaccharide in Eryngiumarten

Zeitschrift für Naturforschung B, 1969
Aus Wurzeln von Eryngium planum L. wurde ein nichtreduzierendes Trisaccharid isoliert, das sich als 1-Kestose erwies. Dieses Trisaccharid wurde damit erstmalig in Umbelliferen nachgewiesen. Es wird auch in anderen Organen und Eryngiumarten neben einem weiteren, noch nicht identifizierten Oligosaccharid sowie Saccharose, Glucose und Fructose angetroffen.
openaire   +3 more sources

Nanodroplet Array Platform for Integrated Synthesis and Screening of MEK Inhibitors: a Miniaturized Approach to Early Drug Discovery

Angewandte Chemie International Edition, EarlyView.
We present a nanodroplet array platform that integrates solid‐phase synthesis, MALDI‐MS analysis, and cell‐based screening. Using nanoliter droplets, we synthesized and tested 325 potential MEK inhibitors and identified 46 active compounds. This miniaturized approach combines chemistry and biology on a single chip, reducing time, cost, and material use
Maximilian Seifermann, Julius Höpfner, Liana Bauer, Divya Varadharajan, Stefan Schmidt, Björn Fröhlich, Benjamin Wellenhofer, Charlotte Luchena, Carsten Hopf, Anna A. Popova, Pavel A. Levkin   +10 more
wiley   +1 more source