Results 81 to 90 of about 420,121 (305)

Fucosylation Is a Promising Target for Cancer Diagnosis and Therapy

open access: yesBiomolecules, 2012
Oligosaccharides, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules.
Shinichiro Shinzaki   +8 more
doaj   +1 more source

Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture

open access: yesAdvanced Science, EarlyView.
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou   +4 more
wiley   +1 more source

Synthesis of O-Amino Sugars and Nucleosides

open access: yesMolecules, 2018
Nucleic acids and carbohydrates are essential biomolecules involved in numerous biological and pathological processes. Development of multifunctional building blocks based on nucleosides and sugars is in high demand for the generation of novel ...
Na Chen, Juan Xie
doaj   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

open access: yesAdvanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan   +7 more
wiley   +1 more source

Screening of a Library of Oligosaccharides Targeting Lectin LecB of Pseudomonas Aeruginosa and Synthesis of High Affinity Oligoglycoclusters

open access: yesMolecules, 2018
The Gram negative bacterium Pseudomonas aeruginosa (PA) is an opportunistic bacterium that causes severe and chronic infection of immune-depressed patients.
Lucie Dupin   +13 more
doaj   +1 more source

Removal of Small-Molecular Byproducts from Crude Fructo-Oligosaccharide Preparations by Fermentation Using the Endospore-Forming Probiotic Bacillus coagulans

open access: yesFermentation, 2020
Short-chain prebiotic fructo-oligosaccharides (FOS) produced by enzymatic conversion from sucrose often contains high concentration of monosaccharides as byproducts.
Rong Fan   +3 more
doaj   +1 more source

Mapping and Quantification of the Major Oligosaccharide Components of Heparin [PDF]

open access: yes, 1988
Biochemical Journal, 254, 781-787Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.A
Loganathan, D.   +5 more
core   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

open access: yesAngewandte Chemie, EarlyView.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber   +4 more
wiley   +1 more source

Synthetic oligosaccharide used in this study.

open access: yes, 2014
Synthetic oligosaccharide used in this study.
Frederic Sorgeloos (5659216)   +16 more
core   +1 more source

Synthesis of Streptococcus pneumoniae serotype 9V oligosaccharide antigens

open access: yesBeilstein Journal of Organic Chemistry, 2020
Streptococcus pneumoniae (SP) bacteria cause serious invasive diseases. SP bacteria are covered by a capsular polysaccharide (CPS) that is a virulence factor and the basis for SP polysaccharide and glycoconjugate vaccines.
Sharavathi G. Parameswarappa   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy