Results 61 to 70 of about 420,121 (305)

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

open access: yesAdvanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi   +8 more
wiley   +1 more source

Intracellular Delivery of Hydrophilic Glycans Using Superchaotropic Clusters

open access: yesAngewandte Chemie, EarlyView.
Superchaotropic boron clusters are demonstrated to deliver hydrophilic glycans directly into mammalian cells, removing the need for acetylation and cytotoxic solvents such as DMSO. Azido glycans for metabolic oligosaccharide engineering, and trehalose, were delivered and the successful azido‐labelling of glycoproteins, cell surface glycans, and ...
Qiao Tang   +2 more
wiley   +2 more sources

Cap-and-Tag Solid Phase Oligosaccharide Synthesis

open access: yes, 2016
A new “cap-and-tag” strategy is applied to solid phase oligosaccharide synthesis. Acetyl-capping and fluorous-tagging allowed for the facile separation of the desired F-tagged oligosaccharide from the acetyl-capped deletion sequences using fluorous solid
Frédéric R. Carrel (2447857)   +1 more
core   +2 more sources

Chitan oligosaccharide and salicylic acid differently activate arteminisin production and gene expression in Artemisia annua

open access: yes, 2011
Artemisia annua L. is a traditional Chinese medicinal plant used for treatment of malaria. Artemisinin which accumulated in the glandular trichomes of this plant is the primary anti-malaria component of the Artemisia annua plant extraction.
尹恒   +4 more
core   +1 more source

Characterization, Antioxidant and Antitumor Activities of Oligosaccharides Isolated from Evodia lepta (Spreng) Merr. by Different Extraction Methods

open access: yesAntioxidants, 2021
Evodia lepta (E. lepta) is a traditional Chinese herbal medicine with various biological activities. One of the active components of this widely used medicinal plant is believed to be an oligosaccharide. The extraction yields, structural characteristics,
Feng Xiong   +6 more
doaj   +1 more source

The structure of CD oligosaccharide.

open access: yes, 2014
The structure of CD oligosaccharide.
Yuqin Li (561666)   +3 more
core   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

open access: yesAdvanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan   +11 more
wiley   +1 more source

Glycosylation reactions mediated by hypervalent iodine: application to the synthesis of nucleosides and carbohydrates

open access: yesBeilstein Journal of Organic Chemistry, 2018
To synthesize nucleoside and oligosaccharide derivatives, we often use a glycosylation reaction to form a glycoside bond. Coupling reactions between a nucleobase and a sugar donor in the former case, and the reaction between an acceptor and a sugar donor
Yuichi Yoshimura   +4 more
doaj   +1 more source

Dietary soy galactooligosaccharides affect the performance, intestinal function, and gut microbiota composition of growing chicks

open access: yesPoultry Science, 2023
: The objective of this experiment was to investigate the effects of the dietary soy galactooligosaccharides (GOS), raffinose and stachyose, on performance, gastrointestinal health, and systemic stress in young broilers.
K.D. Teague   +9 more
doaj   +1 more source

Multifunctionality of Campylobacter jejuni sialyltransferase CstII: Characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities

open access: yes, 2008
CstII from bacterium Campylobacter jejuni strain OH4384 has been previously characterized as a bifunctional sialyltransferase having both α2,3-sialyltransferase (GM3 oligosaccharide synthase) and α2,8-sialyltransferase (GD3 oligosaccharide synthase ...
Huang, Shengshu   +7 more
core   +1 more source

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