Results 51 to 60 of about 422,886 (261)

RNAi-Mediated Silencing of Pgants Shows Core 1 O-Glycans Are Required for Pupation in Tribolium castaneum

Frontiers in Physiology, 2021
Protein glycosylation is one of the most common and most important post-translational modifications. Despite the growing knowledge on N-glycosylation, the research on O-glycosylation is lagging behind.
Weidong Li, Weidong Li, Kristof De Schutter, Els J. M. Van Damme, Guy Smagghe   +4 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Advanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang, Shunmuga Nathan Shunmuga Nainar, Bing‐Han Zhuang, Shun‐Mao Yang, Hong‐Cheu Lin, Yang‐Hsiang Chan   +5 more
wiley   +1 more source

Characterization, Antioxidant and Antitumor Activities of Oligosaccharides Isolated from Evodia lepta (Spreng) Merr. by Different Extraction Methods

Antioxidants, 2021
Evodia lepta (E. lepta) is a traditional Chinese herbal medicine with various biological activities. One of the active components of this widely used medicinal plant is believed to be an oligosaccharide. The extraction yields, structural characteristics,
Feng Xiong, Hui-Xian Liang, Zhi-Jing Zhang, Taifo Mahmud, Albert S. C. Chan, Xia Li, Wen-Jian Lan   +6 more
doaj   +1 more source

Effect of germination on the oligosaccharide content of lupin species

, 1992
The effect of germination on the oligosaccharide content of two lupin species (Lupinus albus and Lupinus luteus) was determined with an extraction method, using aqueous methanol and purification through ion-exchange minicolumns.
Muzquiz, M., Fenwick, G. R., Rey, Carmen, Cuadrado Hoyos, María Carmen   +3 more
core   +1 more source

Large‐Scale and Cost‐Effective Fabrication of Ultra‐Thin, Biodegradable Microelectrode Arrays and Pressure Sensors Using Laser Micromachining

Advanced Materials Technologies, EarlyView.
A mask‐free and cost‐effective UV‐pico‐second laser‐based microfabrication method is proposed to fabricate large‐area biodegradable microelectrode arrays and pressure sensors. These devices demonstrate low impedance, good conformability, excellent biocompatibility, and rapid degradation, providing a new route for next‐generation transient electronics ...
Bhavani Prasad Yalagala, Asfand Tanwear, María Cerezo‐Sánchez, Hossein Parvizi, Morteza Amjadi, Hadi Heidari   +5 more
wiley   +1 more source

Glycosylation reactions mediated by hypervalent iodine: application to the synthesis of nucleosides and carbohydrates

Beilstein Journal of Organic Chemistry, 2018
To synthesize nucleoside and oligosaccharide derivatives, we often use a glycosylation reaction to form a glycoside bond. Coupling reactions between a nucleobase and a sugar donor in the former case, and the reaction between an acceptor and a sugar donor
Yuichi Yoshimura, Hideaki Wakamatsu, Yoshihiro Natori, Yukako Saito, Noriaki Minakawa   +4 more
doaj   +1 more source

Dietary soy galactooligosaccharides affect the performance, intestinal function, and gut microbiota composition of growing chicks

Poultry Science, 2023
: The objective of this experiment was to investigate the effects of the dietary soy galactooligosaccharides (GOS), raffinose and stachyose, on performance, gastrointestinal health, and systemic stress in young broilers.
K.D. Teague, G. Tellez-Isaias, Jianmin Chai, V. Petrone-Garcia, C.N. Vuong, A. Blanch, S.H. Rasmussen, K. Brown, Jiangchao Zhao, S.J. Rochell   +9 more
doaj   +1 more source

Oligosaccharide release from frozen and paraffin-wax-embedded archival tissues.

, 1996
Altered glycosylation is a feature of many solid tissue diseases such as ulcerative colitis, Crohn's disease, cancer, and connective tissue disorders. Conventionally, oligosaccharide changes have been studied by immunohistochemical techniques.
Streets, A.J., Brooks, S.A., Leathem, A.J., Dwek, M.V., Harvey, D.J.   +4 more
core   +1 more source

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

Advanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu, Yufan Xie, Lanxin Wang, Luyan Ma, Xiaofei Ge, Jiawei Wang   +5 more
wiley   +1 more source