Results 51 to 60 of about 403,843 (306)

Genome Analysis of a Potential Novel Vibrio Species Secreting pH- and Thermo-Stable Alginate Lyase and Its Application in Producing Alginate Oligosaccharides

Marine Drugs
Alginate lyase is an attractive biocatalyst that can specifically degrade alginate to produce oligosaccharides, showing great potential for industrial and medicinal applications.
Ke Bao, Miao Yang, Qianhuan Sun, Kaishan Zhang, Huiqin Huang   +4 more
doaj   +1 more source

RNAi-Mediated Silencing of Pgants Shows Core 1 O-Glycans Are Required for Pupation in Tribolium castaneum

Frontiers in Physiology, 2021
Protein glycosylation is one of the most common and most important post-translational modifications. Despite the growing knowledge on N-glycosylation, the research on O-glycosylation is lagging behind.
Weidong Li, Weidong Li, Kristof De Schutter, Els J. M. Van Damme, Guy Smagghe   +4 more
doaj   +1 more source

Docking of limonoids to PPA-oligosaccharide complex.

, 2015
Limonoids docked on PPA-oligosaccharide complex (A). Putative mode of interaction between azadiradione, gedunin and with PPA-oligosaccharide complex (B, C).
Sudha Ponnusamy (813860), Saikat Haldar (813861), Ameeta RaviKumar (813865), Smita Zinjarde (813863), Fayaj Mulani (813862), Hirekodathakallu Thulasiram (813864)   +5 more
core   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Carbohydrate Physicochemical Properties: The Innate Hydrogen Bond Donating Capacities of α‐Glucoside and α‐Galactoside Alcohol Groups

Angewandte Chemie, EarlyView.
Experimental determination of the innate hydrogen bond donating capacities of the glucose and galactose non‐anomeric alcohols revealed significant variations depending on position and relative configuration, which were quantified on the pKAHY scale, relevant for MedChem purposes, hence providing another tool toward rational glycomimetic development ...
Mrinal Naskar, Zhong Wang, Krunal Patel, Branko De Baets, Anaïs Goupille, Davy Sinnaeve, Eric Renault, Jean‐Yves Le Questel, Bruno Linclau   +8 more
wiley   +2 more sources

Chitan oligosaccharide and salicylic acid differently activate arteminisin production and gene expression in Artemisia annua

, 2011
Artemisia annua L. is a traditional Chinese medicinal plant used for treatment of malaria. Artemisinin which accumulated in the glandular trichomes of this plant is the primary anti-malaria component of the Artemisia annua plant extraction.
尹恒, 杜昱光, AndersKjar, YuguangDu, KaiGrevsen   +4 more
core   +1 more source

THE PRELIMINARY STUDY OF ANTIOXIDANT ACTIVITY FROM XYLO-OLIGOSACCHARIDE OF CORNCOB (ZEA MAYS) HYDROLYSIS PRODUCT WITH ENDO-β-XYLANASE ENZYME

Indonesian Journal of Tropical and Infectious Disease, 2016
Xylo-oligosaccharide derived from corncob hemicellulose has been reported to possess antioxidant activity. In order to assess the effective scavenging of xylo-oligosaccharide, we conducted in vitro studies based on self-made xylo-oligosaccharide with ...
Laura Navika Yamani, Alfinda Novi Kristanti, Ni Nyoman Puspaningsih   +2 more
doaj   +1 more source

Oligosaccharide excretion in adult Gaucher disease

, 1998
Gaucher disease is a lysosomal storage disease characterized by storage of glucocerebroside due to lysosomal glucocerebrosidase deficiency. Increased urinary excretion of sialyloligosaccharides and mannosylglycoasparagines has been described for two ...
de Jong, J. G., J. M. F. G. Aerts, R. A. Wevers, van Pelt, J., Aerts, J.M.F.G., Hollak, C. E., Weely, S. van, Wevers, R. A., Liebrand-van Sambeek, M. L., S. van Weely, Hollak, C.E.M., Wevers, R.A., C. E. M. Hollak, van Woerkom, L. M., M. L. F. Liebrand‐van Sambeek, van Weely, S., Pelt, J. van, J. G. N. de Jong, Aerts, J. M., Liebrand-van Sambeek, M.L.F., Jong, J.G.N. de, J. van Pelt, L. M. J. van Woerkom, Woerkom, L.M.J. van, Woerkum, C.M.J. van   +24 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

3‐Deoxy‐3‐Fluoro Mannuronic Acid Alginates: Stereoselective Automated Synthesis and Conformational Behaviour

Angewandte Chemie, EarlyView.
The impact of C‐3 fluorination on the synthesis and conformation of alginate oligosaccharides is investigated. A C‐3‐fluoro mannuronic acid building block is generated and shown to react with high β‐selectivity. Automated glycan assembly enables access to uniquely fluorinated mannuronic acid alginates where deoxyfluorination is shown not to perturb the
Sean T. Evans, Nishu Yadav, Wouter A. Remmerswaal, Daan Hoogers, Koen N. A. van de Vrande, Sarah Hosking, Ana Poveda, Jeroen D. C. Codée, Jesús Jiménez‐Barbero, Martina Delbianco, Gavin J. Miller   +10 more
wiley   +2 more sources