Results 51 to 60 of about 390,913 (262)

Glycosylation reactions mediated by hypervalent iodine: application to the synthesis of nucleosides and carbohydrates

Beilstein Journal of Organic Chemistry, 2018
To synthesize nucleoside and oligosaccharide derivatives, we often use a glycosylation reaction to form a glycoside bond. Coupling reactions between a nucleobase and a sugar donor in the former case, and the reaction between an acceptor and a sugar donor
Yuichi Yoshimura, Hideaki Wakamatsu, Yoshihiro Natori, Yukako Saito, Noriaki Minakawa   +4 more
doaj   +1 more source

Dietary soy galactooligosaccharides affect the performance, intestinal function, and gut microbiota composition of growing chicks

Poultry Science, 2023
: The objective of this experiment was to investigate the effects of the dietary soy galactooligosaccharides (GOS), raffinose and stachyose, on performance, gastrointestinal health, and systemic stress in young broilers.
K.D. Teague, G. Tellez-Isaias, Jianmin Chai, V. Petrone-Garcia, C.N. Vuong, A. Blanch, S.H. Rasmussen, K. Brown, Jiangchao Zhao, S.J. Rochell   +9 more
doaj   +1 more source

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

Advanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi, Ruirui Xu, Daoan Wang, Guobin Yin, Xinjing Wang, Haiqin Chen, Guocheng Du, Jian Chen, Zhen Kang   +8 more
wiley   +1 more source

Ứng dụng lysozyme để tạo chế phẩm bột oligosaccharide từ vỏ tôm thẻ chân trắng (Litopennaeus vannamei)

Tạp chí Khoa học Đại học Cần Thơ, 2019
Nghiên cứu được thực hiện nhằm khảo sát ảnh hưởng của thời gian, pH, nhiệt độ và nồng độ cơ chất lên quá trình thủy phân chitin bằng lysozyme từ lòng trắng trứng gà Hisex Brown để tạo bột oligosaccharide.
Võ Văn Song Toàn, Dương Thị Hương Giang, Lê Tấn Hòa, Nguyễn Thị Cẩm Giang, Kim Thị Thu Xương, Trương Thị Thanh Tuyền, Lê Ngọc Tuyết, Nguyễn Ngọc Phương Vy, Trần Nhân Dũng   +8 more
doaj   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Structure of a Sialo-Oligosaccharide from Glycophorin in Carp Red Blood Cell Membranes

Membranes, 2014
We isolated a high-purity carp glycophorin from carp erythrocyte membranes and prepared the oligosaccharide fraction from glycophorin by β-elimination [1].
Takahiko Aoki, Kenji Chimura, Hikaru Sugiura, Yasuko Mizuno   +3 more
doaj   +1 more source

Application of Paramagnetic NMR-Validated Molecular Dynamics Simulation to the Analysis of a Conformational Ensemble of a Branched Oligosaccharide

Molecules, 2012
Oligosaccharides of biological importance often exhibit branched covalent structures and dynamic conformational multiplicities. Here we report the application of a method that we developed, which combined molecular dynamics (MD) simulations and ...
Koichi Kato, Takumi Yamaguchi, Ying Zhang, Sayoko Yamamoto   +3 more
doaj   +1 more source

Fucosylation Is a Promising Target for Cancer Diagnosis and Therapy

Biomolecules, 2012
Oligosaccharides, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules.
Shinichiro Shinzaki, Hitoshi Matsumoto, Tsutomu Nakagawa, Mika Terao, Cheng-Cheng Tan, Naoko Terao, Kenta Moriwaki, Eiji Miyoshi, Yoshihiro Kamada   +8 more
doaj   +1 more source

Synthesis of O-Amino Sugars and Nucleosides

Molecules, 2018
Nucleic acids and carbohydrates are essential biomolecules involved in numerous biological and pathological processes. Development of multifunctional building blocks based on nucleosides and sugars is in high demand for the generation of novel ...
Na Chen, Juan Xie
doaj   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

Angewandte Chemie, EarlyView.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source