Results 131 to 140 of about 458,280 (341)
2D separation and profiling of complex oligosaccharide mixtures [PDF]
, 2011 Oligosaccharides present in various natural sources can contain different linkages, susbstitutions and building blocks with the same mass. Oligosaccharide mixtures often contain these isomeric and isobaric structures, which causes their complexity. These
Bouly, Nathalie +3 more
core +1 more source
BMEMat, EarlyView.Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
NMR Line Shape Analysis of a Multi-state Ligand Binding Mechanism in Chitosanase [PDF]
, 2017 Chitosan interaction with chitosanase was examined through analysis of spectral line shapes in the NMR HSQC titration experiments. We established that the substrate, chitosan hexamer, binds to the enzyme through the three-state induced-fit mechanism with
Brzezinski, Ryszard +7 more
core +1 more source
HUMAN INTESTINAL DISACCHARIDASES AND HEREDITARY DISACCHARIDE INTOLERANCE. THE HYDROLYSIS OF SUCROSE, ISOMALTOSE, PALATINOSE (ISOMALTULOSE), AND A 1,6-α-OLIGOSACCHARIDE (ISOMALTO-OLIGOSACCHARIDE) PREPARATION* [PDF]
, 1963 Arne Dahlqvist +3 more
openalex +1 more source
Reactivity of Carbohydrate Phosphodiesters, Potential Targets of Antibacterial Agents
Chemistry &Biodiversity, EarlyView.A simple carbohydrate phosphodiester model was synthesized to compare the reactivity of phosphodiester bonds within carbohydrates and RNA. ABSTRACT While monosaccharide units in bacterial carbohydrates may be linked with phosphodiester bonds, human carbohydrates exclusively contain glycosidic linkages.
Eero Sillanpää +2 more
wiley +1 more source
ChemBioChem, EarlyView.At the intersection of chemical biology, plant imaging, and contemporary art, this review introduces the concept of chembioart. By tracing how chemical reporters illuminate plant biomolecules in vivo, their role not only in advancing scientific understanding but also in inspiring transdisciplinary collaborations and visual expression is highlighted ...
Marie Hinnebo +4 more
wiley +1 more source
Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research
ChemBioChem, EarlyView.The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley +1 more source
STUDIES ON CARBOHYDRATE-METABOLIZING ENZYMES. V. SYNTHESIS OF OLIGOSACCHARIDES FROM MALTOSE AND GLUCOSE BY YEAST ENZYMES* [PDF]
, 1960 Zeenat H. Gunja, D. J. Manners
openalex +1 more source
C‐6‐Modified 2‐F‐Fucose Derivatives as Inhibitors of Fucosyltransferases
ChemBioChem, EarlyView.A series of C6‐modified guanosine‐diphosphate‐2‐F‐fucose analogs and corresponding prodrugs are designed, synthesized, and biologically evaluated as inhibitors of cellular fucosylation. Certain analogs potently inhibit fucosyltransferases (FUT) FUT1, 3, 6, and 9 while showing minimal activity for FUT8, highlighting the potential for selective FUT ...
Yanyan Liu, Geert‐Jan Boons
wiley +1 more source
ChemistryEurope, EarlyView.This Perspective focuses on photocatalyst‐free, photoinduced modifications of biomolecules, emphasizing transformations mediated by electron donor–acceptor complexes. Mechanistic aspects, current limitations, and future opportunities are discussed, providing insight into the field of bioconjugation.
Milene Hornink +3 more
wiley +1 more source