Results 221 to 230 of about 422,886 (261)

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

Oligosaccharide prebiotics in functional foods and therapeutics: innovations and challenges. [PDF]

3 Biotech
Sandra KS, Vithalkar MP, Beere V, Bharath HB, Satyanarayana B, Rafiq M, Nayak Y.   +6 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Single-monosaccharide resolution glycan profiling enabled by the nanopipette. [PDF]

Chem Sci
Ma H, Li YX, Xu Z, Ma W, Xia B, Gao Z, Li T, Ying YL.   +7 more
europepmc   +1 more source

Converging GWAS and Genome Editing Decrypts MsCBF8‐MsGolS2 Regulatory Module for Drought Tolerance Without Yield Penalty in Medicago sativa

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought constitutes a major abiotic stress limiting alfalfa productivity. To elucidate the genetic basis of drought tolerance, a genome‐wide association study (GWAS) was conducted in alfalfa, which identified a CBF/DREB1 family transcription factor designated MsCBF8.
Yangyang Zhang, Xueqian Jiang, Tian Zhang, Huajuan Leng, Jing Cui, Xu Jiang, Lili Zhang, Zhen Wang, Tiejun Zhang, Qingchuan Yang, Xue Wang, Junmei Kang   +11 more
wiley   +1 more source

Mechanistic Insights into β‑1,6-Branch Recognition and Orientation-Selective Hydrolysis by <i>Endo</i>-β-1,3-Glucanase Using Synthetic β‑Glucan Probes. [PDF]

ACS Bio Med Chem Au
Miyagawa A, Yamaguchi T, Oda M, Yamamura H.   +3 more
europepmc   +1 more source

Sugars as Central Integrators of Plant Immunity and Stress Responses

Plant, Cell &Environment, EarlyView.
ABSTRACT Sugars are fundamental metabolites that sustain plant growth and development, but accumulating evidence demonstrates that they also function as regulatory hubs in plant defence. In this review, we synthesise current knowledge on how carbohydrate dynamics coordinate metabolism, signalling, and structural responses to shape plant resistance ...
Anna Wlazło, Anna Barczak‐Brzyżek, Marcin Filipecki   +2 more
wiley   +1 more source

Multi-Enzymatic Cascade Synthesis of Oligosaccharide Haptens from <i>Streptococcus suis</i> Serotype 2 and 1/2 Capsular Polysaccharides and Antigenicity Evaluation. [PDF]

JACS Au
Zhao J, Wang H, Xu X, Liang M, Liu X, Gu G.   +5 more
europepmc   +1 more source

The Ash Dieback Pathogen Resists the Chemical Defences of Its Host Tree, European Ash, by Depleting Them From the Growth Medium

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant pathogenic fungi are major drivers of disease in forest trees, often causing substantial ecological and economic damage. Ash dieback, caused by the ascomycete Hymenoscyphus fraxineus, has resulted in the widespread decline of Fraxinus excelsior populations throughout Europe.
Björn Lichnock, Niklas Gentsch, Antonia Papadopulos, Natalia Rauch, Michael Reichelt, Gitta Langer, Susanne Jochner‐Oette, Jonathan Gershenzon, Maximilian Lehenberger   +8 more
wiley   +1 more source

The impact of human milk oligosaccharides and galacto-oligosaccharides on the growth of early life pathogenic gut bacteria. [PDF]

Front Microbiol
Schlösser JTS, Unger WWJ, de Bruijn ACJM, Delsing DJ, Groeneveld A, Nauta A, Folkerts G, Wösten MMSM, Braber S.   +8 more
europepmc   +1 more source