Results 81 to 90 of about 458,280 (341)

Fucosylation Is a Promising Target for Cancer Diagnosis and Therapy

Biomolecules, 2012
Oligosaccharides, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules.
Shinichiro Shinzaki, Hitoshi Matsumoto, Tsutomu Nakagawa, Mika Terao, Cheng-Cheng Tan, Naoko Terao, Kenta Moriwaki, Eiji Miyoshi, Yoshihiro Kamada   +8 more
doaj   +1 more source

Formulating Smart All‐in‐One Chitosan Hydrogel for High Performance Wound Dressing

Advanced Healthcare Materials, EarlyView.
An innovative approach to fabricating a thermosensitive, highly swelling, degradable, and antibacterial hydrogel composed of a chitosan‐g‐NIPAAm/PVA/PVP copolymer, integrated with AgNPs, for use in wound dressing applications. The hydrogel demonstrates enhanced performance, accelerating the wound healing process.
Chia‐Chi Lin, Andi Magattang Gafur Muchlis, Ren‐Jei Chung, Ssu Yu Huang, Michal Martinka, Syang‐Peng Rwei, Aivaras Kareiva, Jen‐Chang Yang, Chun Che Lin   +8 more
wiley   +1 more source

Decoding a Gut Commensal Signal: Structural and Immunological Profiling of Segatella Copri Lipopolysaccharide

Angewandte Chemie, EarlyView.
The lipopolysaccharide (LPS) of Segatella copri is a structurally unique, immunomodulatory glycoconjugate. Combining mass spectrometry (MS), nuclear magnetic resonance (NMR), and cytometry by time‐of‐flight (CyTOF), we uncover a rough‐type LPS with reduced TLR4 agonism and selective monocyte effects, further highlighting the key role of LPS chemistry ...
Luca De Simone Carone, Giusi Barra, Roberta Cirella, Marcello Ziaco, Marcello Mercogliano, Francesca Olmeo, Emanuela Andretta, Valentina Mazziotti, Carmela Fusco, Giuliana D'Ippolito, Katarzyna Anna Duda, Freda M. Farquharson, Petra Louis, Angelo Fontana, Alba Silipo, Antonio Molinaro, Fabrizio Chiodo, Flaviana Di Lorenzo   +17 more
wiley   +2 more sources

Genome Analysis of a Potential Novel Vibrio Species Secreting pH- and Thermo-Stable Alginate Lyase and Its Application in Producing Alginate Oligosaccharides

Marine Drugs
Alginate lyase is an attractive biocatalyst that can specifically degrade alginate to produce oligosaccharides, showing great potential for industrial and medicinal applications.
Ke Bao, Miao Yang, Qianhuan Sun, Kaishan Zhang, Huiqin Huang   +4 more
doaj   +1 more source

Synthesis of O-Amino Sugars and Nucleosides

Molecules, 2018
Nucleic acids and carbohydrates are essential biomolecules involved in numerous biological and pathological processes. Development of multifunctional building blocks based on nucleosides and sugars is in high demand for the generation of novel ...
Na Chen, Juan Xie
doaj   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

Iron‐Catalyzed Highly Stereospecific Glycosylation with Glycal Epoxides

Angewandte Chemie, EarlyView.
We report an iron‐catalyzed, highly stereospecific glycosylation method with glycal epoxides, which is effective for a broad range of substrates, including previously challenging, sterically hindered secondary acceptors and glucuronic ester epoxide donors.
Xiao‐Wen Zhang, Le Yin, Dakang Zhang, Zixiang Jiang, Pinzhi Wang, Hao Xu   +5 more
wiley   +2 more sources

Honeysuckle‐Derived Nanovesicles Regulate Gut Microbiota for the Treatment of Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study explores honeysuckle‐derived nanovesicles (HNVs) for treating inflammatory bowel disease. Orally administered HNVs alleviates colitis in mice by repairing the gut barrier, reducing inflammation, and restoring a healthy gut microbiota.
Yuanyuan Wang, Yuanhao Zhou, Qingyuan Wu, Yishu Li, Yilin Huang, Kexin Yu, Ping Li, Zhenye Lv, Haotian Liu, Hai Zou, Huiyu Liu, Xiaozhou Mou   +11 more
wiley   +1 more source

Effects of Prebiotics on Antioxidant Activity of Goat Milk Fermented by Lactobacillus plantarum L60

Acta Universitatis Cibiniensis. Series E: Food Technology, 2017
The production of functional fermented goat milk with synbiotic have attracted widespread attention recently with the purpose of promoting health.
Shu Guowei, He Yunxia, Wan Hongchang, Hui Yixin, Li Hong   +4 more
doaj   +1 more source

Screening of a Library of Oligosaccharides Targeting Lectin LecB of Pseudomonas Aeruginosa and Synthesis of High Affinity Oligoglycoclusters

Molecules, 2018
The Gram negative bacterium Pseudomonas aeruginosa (PA) is an opportunistic bacterium that causes severe and chronic infection of immune-depressed patients.
Lucie Dupin, Mathieu Noël, Silvère Bonnet, Albert Meyer, Thomas Géhin, Ludovic Bastide, Mialy Randriantsoa, Eliane Souteyrand, Claire Cottin, Gérard Vergoten, Jean-Jacques Vasseur, François Morvan, Yann Chevolot, Benoît Darblade   +13 more
doaj   +1 more source